- image analysis of host-pathogen interactions
- image-based quantitative characterization of immune cells
- analysis of live-cell image data
|since 2013||Postdoctoral researcher in the group Applied Systems Biology at Hans Knöll Institute|
|2014||PhD in Physical Chemistry at the Friedrich Schiller University Jena|
|2010||Diploma in Medical Cybernetics at Siberian State Medical University in Tomsk, Russia|
(2021) Enhanced segmentation of label-free cells for automated migration and interaction tracking. Cytometry Part A , 1-12.
(2021) Targeting complement C5a receptor 1 for the treatment of immunosuppression in sepsis. Mol Ther 29(1), 338-346.
(2020) MISA++: A standardized interface for automated bioimage analysis. SoftwareX 11, 100405.
(2020) Dynamic spherical harmonics approach for shape classification of migrating cells. Sci Rep 10(1), 6072.
(2020) DeconvTest: Simulation framework for quantifying errors and selecting optimal parameters of image deconvolution. J Biophotonics 13(4), e201960079.
(2020) Human neutrophils produce antifungal extracellular vesicles against Aspergillus fumigatus. mBio 11(2), e00596-20.
(2019) Automated tracking of label-free cells with enhanced recognition of whole tracks. Sci Rep 9(1), 3317.
(2019) A three-dimensional immunocompetent intestine-on-chip model as in vitro platform for functional and microbial interaction studies. Biomaterials 220, 119396.
(2018) Modeling hemolytic-uremic syndrome: In-depth characterization of distinct murine models reflecting different features of human disease. Front Immunol 9, 1459.
(2018) Waffenübergabe im Immunsystem. Laborjournal 4, 40-43. (Review)
(2018) Molecular signatures of liver dysfunction are distinct in fungal and bacterial infections in mice. Theranostics 8(14), 3766-3780.
(2018) Untangling cell tracks: Quantifying cell migration by time lapse image data analysis. Cytometry A 93(3), 357-370.
(2017) Mast cells acquire MHCII from dendritic cells during skin inflammation. J Exp Med 214(12), 3791-3811.
(2017) Fully automated evaluation of total glomerular number and capillary tuft size in murine nephritic kidneys using lightsheet microscopy. J Am Soc Nephrol 28(2), 452-459.
(2016) FHR3 Blocks C3d-Mediated Coactivation of Human B Cells. J Immunol 197(2), 620-629.
(2015) Texture analysis and classification in coherent anti-Stokes Raman scattering (CARS) microscopy images for automated detection of skin cancer. Computerized Medical Imaging and Graphics 43, 36-43.
(2015) Image-based Systems Biology of Infection. Cytometry A 87(6), 462-470.
(2013) Hyperspectral unmixing of Raman micro-images for assessment of morphological and chemical parameters in non-dried brain tumor specimens. Anal Bioanal Chem 405(27), 8719-8728.
(2013) Automated seeding-based nuclei segmentation in nonlinear optical microscopy. Applied optics 52(28), 6979-6994.
(2012) Towards automated segmentation of cells and cell nuclei in nonlinear optical microscopy. J Biophotonics 5(11-12), 878-888.
(2012) Interpreting CARS images of tissue within the C-H-stretching region. J Biophotonics 5(10), 729-733.
(2011) Automated classification of healthy and keloidal collagen patterns based on processing of SHG images of human skin. J Biophotonics 4(9), 627-636.
(2011) Towards multimodal nonlinear optical tomography–experimental methodology. Laser Physics Letters 8(8), 617-624.