Curriculum vitae

Main Research Areas
  • Topic of the PhD thesis: "Agent-based modelling of the spatio-temporal interaction between immune cells and human-pathogenic fungi"
  • agent-based modelling and simulation of host-pathogen interactions
  • interaction of immune cells and Candida albicans in human blood
  • migration dynamics of immune cells as a consequence of fungal infections
Professional Career
since 2018 Postdoctoral researcher in the group Applied Systems Biology at Hans Knöll Institute
2018 PhD in Bioinformatics at the Friedrich Schiller University Jena
2013 M.Sc. in Bioinformatics at the Friedrich Schiller University Jena
2011 B.Sc. in Bioinformatics at the Friedrich Schiller University Jena

Publications

Lehnert T*, Leonhardt I*, Timme S, Thomas-Rüddel D, Bloos F, Sponholz C, Kurzai O, Figge MT#, Hünniger K# (2021) Ex vivo immune profiling in patient blood enables quantification of innate immune effector functions. Sci Rep 11(1), 12039.
Blickensdorf M, Timme S, Figge MT (2020) Hybrid agent-based modeling of Aspergillus fumigatus infection to quantitatively investigate the role of Pores of Kohn in human alveoli. Front Microbiol 11, 1951.
Blickensdorf M, Timme S, Figge MT (2019) Comparative assessment of aspergillosis by virtual infection modeling in murine and human lung. Front Immunol 10, 142.
Prauße MTE, Lehnert T, Timme S, Hünniger K, Leonhardt I, Kurzai O, Figge MT (2018) Predictive virtual infection modeling of fungal immune evasion in human whole blood. Front Immunol 9, 560.
Timme S, Lehnert T, Prauße MTE, Hünniger K, Leonhardt I, Kurzai O, Figge MT (2018) Quantitative simulations predict treatment strategies against fungal infections in virtual neutropenic patients. Front Immunol 9, 667.
Pollmächer J, Timme S, Schuster S, Brakhage AA, Zipfel PF, Figge MT (2016) Deciphering the counterplay of Aspergillus fumigatus infection and host inflammation by evolutionary games on graphs. Sci Rep 6, 27807.
Lehnert T*, Timme S*, Pollmächer J, Hünniger K, Kurzai O, Figge MT (2015) Bottom-up modeling approach for the quantitative estimation of parameters in pathogen-host interactions. Frontiers in Microbiology 6(608), *authors contributed equally.
Medyukhina A, Timme S, Mokhtari Z, Figge MT (2015) Image-based Systems Biology of Infection. Cytometry A 87(6), 462-470.