Belyaev I*, Praetorius JP*, Medyukhina A, Figge MT; * shared first authors (2021) Enhanced segmentation of label-free cells for automated migration and interaction tracking. Cytometry Part A , 1-12. Details PubMed Open Access PDF

Campagner A, Ciucci D, Svensson CM, Figge MT, Cabitza F (2021) Ground truthing from multi-rater labeling with three-way decision and possibility theory. Inf Sci 545, 771-790. Details PDF

Kästner B, Hengoju S, Svensson C-M, Figge MT, Rosenbaum MA (2021) Mit Tropfenmikrofluidik zu Hochgeschwindigkeits-Biotechnologie. BIOspektrum 27(3), 260-262. Details PDF

Lehnert T*, Leonhardt I*, Timme S, Thomas-Rüddel D, Bloos F, Sponholz C, Kurzai O, Figge MT**, Hünniger K**; * shared first authors; ** authors contributed equally; corresponding authors (2021) Ex vivo immune profiling in patient blood enables quantification of innate immune effector functions. Sci Rep 11(1), 12039. Details PubMed Open Access PDF

Lehnert T, Prauße MTE, Hünniger K, Praetorius JP, Kurzai O, Figge MT (2021) Comparative assessment of immune evasion mechanisms in human whole-blood infection assays by a systems biology approach. PLOS One 16(4), e0249372. Details PubMed Open Access PDF

Muljajew I*, Huschke S*, Ramoji A, Cseresnyés Z, Hoeppener S, Nischang I, Foo W, Popp J, Figge MT, Weber C, Bauer M, Schubert US**, Press AT**; * shared first authors; ** corresponding authors; (2021) Stealth effect of short polyoxazolines in graft copolymers: Minor changes of backbone end group determine liver cell-type specificity. ACS Nano [Epub ahead of print] Details PubMed

Sommerfeld O, Medyukhina A, Neugebauer S, Ghait M, Ulferts S, Lupp A, König R, Wetzker R, Schulz S, Figge MT, Bauer M, Press AT (2021) Targeting complement C5a receptor 1 for the treatment of immunosuppression in sepsis. Mol Ther 29(1), 338-346. Details PubMed Open Access PDF

Stanford FA, Matthies N, Cseresnyés Z, Figge MT, Hassan MIA, Kerstin Voigt (2021) Expression patterns in reductive iron assimilation and functional consequences during phagocytosis of Lichtheimia corymbifera, an emerging cause of mucormycosis. J Fungi 7(4), 272. Details PubMed Open Access PDF

Blickensdorf M, Timme S, Figge MT (2020) Hybrid agent-based modeling of Aspergillus fumigatus infection to quantitatively investigate the role of Pores of Kohn in human alveoli. Front Microbiol 11, 1951. Details PubMed Open Access

Böttcher B, Hoffmann B, Garbe E, Weise T, Cseresnyés Z, Brandt P, Dietrich S, Driesch D, Figge MT, Vylkova S (2020) The transcription factor Stp2 is important for Candida albicans biofilm establishment and sustainability. Front Microbiol 11, 794. Details PubMed Open Access PDF

Cseresnyes Z*, Hassan MIA*, Dahse HM, Voigt K, Figge MT; * shared first authors (2020) Quantitative impact of cell membrane fluorescence labeling on phagocytosis measurements in confrontation assays. Front Microbiol 11, 1193. Details PubMed Open Access PDF

Deinhardt-Emmer S, Rennert K, Schicke E, Cseresnyés Z, Windolph M, Nietzsche S, Heller R, Siwczak F, Haupt KF, Carlstedt S, Schacke M, Figge MT, Ehrhardt C, Löffler B, Mosig AS (2020) Co-infection with Staphylococcus aureus after primary influenza virus infection leads to damage of the endothelium in a human alveolus-on-a-chip model. Biofabrication 12(2), 025012. Details PubMed Open Access PDF

Figge MT (2020) Advances in quantitative bioimage analysis for proteins and cells. Cytometry Part A 97(4), 344-346. Details PubMed Open Access PDF

Gerst R, Medyukhina A, Figge MT (2020) MISA++: A standardized interface for automated bioimage analysis. SoftwareX 11, 100405. Details Open Access PDF Supplement

Hassan MIA, Kruse JM, Krüger T, Dahse HM, Cseresnyés Z, Blango MG, Slevogt H, Hörhold F, Ast V, König R, Figge MT, Kniemeyer O, Brakhage AA, Voigt K (2020) Functional surface proteomic profiling reveals the host heat-shock protein A8 as a mediator of Lichtheimia corymbifera recognition by murine alveolar macrophages. Environ Microbiol 22(9), 3722-3740. Details PubMed Open Access PDF

Kühne M, Lindemann H, Grune C, Schröder D, Cseresnyés Z, Godmann M, Koschella A, Figge MT, Eggeling C, Fischer D, Heinze T*, Heinzel T*; * corresponding authors (2020) Biocompatible sulfated valproic acid-coupled polysaccharide-based nanocarriers with HDAC inhibitory activity. J Control Release S0168-3659(20), 30577-0. Details PubMed

Marolda A, Hünniger K, Böttcher S, Vivas W, Löffler J, Figge MT, Kurzai O (2020) Candida species-dependent release of IL-12 by dendritic cells induces different levels of NK cell stimulation. J Infect Dis 221(12), 2060-2071. Details PubMed

Medyukhina A*, Blickensdorf M*, Cseresnyés Z, Ruef N, Stein JV, Figge MT; * authors contributed equally (2020) Dynamic spherical harmonics approach for shape classification of migrating cells. Sci Rep 10(1), 6072. Details PubMed Open Access PDF

Medyukhina A, Figge MT (2020) DeconvTest: Simulation framework for quantifying errors and selecting optimal parameters of image deconvolution. J Biophotonics 13(4), e201960079. Details PubMed Open Access PDF Supplement

Schicke E, Cseresnyes Z, Rennert K, Vau V, Haupt KF, Hornung F, Nietzsche S, Swiczak F, Schmidtke M, Koch M, Glück B, Schacke M, Heller R, Mosig AS, Figge MT, Ehrhardt C, Löffler B, Deinhardt-Emmer S (2020) Staphylococcus aureus lung infection results in down-regulation of surfactant protein-A mainly caused by pro-inflammatory macrophages. Microorganisms 8(4), 577. Details PubMed Open Access PDF Supplement

Schmidt F, Thywißen A, Goldmann M, Cunha C, Cseresnyés Z, Schmidt H, Rafiq M, Galiani S, Gräler MH, Chamilos G, Lacerda JF, Campos Jr A, Eggeling C, Figge MT, Heinekamp T, Filler SG, Carvalho A, Brakhage AA (2020) Flotillin-dependent lipid-raft microdomains are required for functional phagolysosomes against fungal infections. Cell Rep 32(7), 108017. Details PubMed PDF

Shopova IA, Belyaev I, Dasari P, Jahreis S, Stroe MC, Cseresnyés Z, Zimmermann AK, Medyukhina A, Svensson CM, Krüger T, Szeifert V, Nietzsche S, Conrad T, Blango MG, Kniemeyer O, von Lilienfeld-Toal M, Zipfel PF, Ligeti E, Figge MT, Brakhage AA (2020) Human neutrophils produce antifungal extracellular vesicles against Aspergillus fumigatus. mBio 11(2), e00596-20. Details PubMed Open Access PDF Supplement

Sreekantapuram S*, Lehnert T*, Prauße MTE, Berndt A, Berens C, Figge MT**, Jacobsen ID**; * authors contributed equally; ** corresponding authors (2020) Dynamic interplay of host and pathogens in an avian whole blood model. Front Immunol 11, 500. Details PubMed Open Access PDF

Tille A, Lehnert T, Zipfel PF, Figge MT (2020) Quantification of factor H mediated self versus non-self discrimination by mathematical modeling. Front Immunol 11, 1911. Details PubMed Open Access PDF

Al-Zaben N*, Medyukhina A*, Dietrich S, Marolda A, Hünniger K, Kurzai O, Figge MT; *authors contributed equally (2019) Automated tracking of label-free cells with enhanced recognition of whole tracks. Sci Rep 9(1), 3317. Details PubMed Open Access PDF Supplement

Blickensdorf M, Timme S, Figge MT (2019) Comparative assessment of aspergillosis by virtual infection modeling in murine and human lung. Front Immunol 10, 142. Details PubMed Open Access PDF Supplement

Dasari P, Koleci N, Shopova I, Wartenberg D, Beyersdorf N, Dietrich S, Sahagun-Ruiz A, Figge MT, Skerka C, Brakhage AA, Zipfel PF (2019) Enolase from Aspergillus fumigatus is a moonlighting and immune evasion protein that binds the human plasma complement proteins factor H, FHL-1, C4BP, and plasminogen. Front Immunol 10, 2573. Details PubMed Open Access PDF

Hassan MIA*, Cseresnyes Z*, Al-Zaben N, Dahse HM, Vilela de Oliveira RJ, Walther G, Voigt K**, Figge MT**; *shared first authors; ** authors contributed equally (2019) The geographical region of origin determines the phagocytic vulnerability of Lichtheimia strains. Environ Microbiol 21(12), 4563-4581. Details PubMed Open Access PDF Supplement

Hirth G, Svensson CM, Böttcher K, Ullrich S, Figge MT, Jungnickel B (2019) Regulation of the germinal center reaction and somatic hypermutation dynamics by homologous recombination. J Immunol 203(6), 1493-1501. Details PubMed

Kresinsky A, Schnöder TM, Jacobsen ID, Rauner M, Hofbauer LC, Ast V, König R, Hoffmann B, Svensson CM, Figge MT, Hilger I, Heidel FH, Böhmer FD, Müller JP (2019) Lack of CD45 in FLT3-ITD mice results in a myeloproliferative phenotype, cortical porosity, and ectopic bone formation. Oncogene 38(24), 4773-4787. Details PubMed

Maurer M, Gresnigt MS, Last A, Wollny T, Berlinghof F, Pospich R, Cseresnyes Z, Medyukhina A, Graf K, Gröger M, Raasch M, Siwczak F, Nietzsche S, Jacobsen ID, Figge MT, Hube B, Huber O, Mosig AS (2019) A three-dimensional immunocompetent intestine-on-chip model as in vitro platform for functional and microbial interaction studies. Biomaterials 220, 119396. Details PubMed

Svensson CM*, Shydkiv O*, Dietrich S, Mahler L, Weber T, Choudhary M, Tovar M, Figge MT**, Roth M**; *authors contributed equally; *corresponding authors; **authors contributed equally (2019) Coding of experimental conditions in microfluidic droplet assays using colored beads and machine learning supported image analysis. Small 15(4), e1802384. Details PubMed

Svensson CM, Figge MT (2019) Künstliche Intelligenz für die biomedizinische Bildgebung. GIT Labor-Fachzeitschrift , (Review) Details Open Access PDF

Tuchscherr L, Pöllath C, Siegmund A, Deinhardt-Emmer S, Hörr V, Svensson CM, Figge MT, Monecke S, Löffler B (2019) Clinical S. aureus isolates vary in their virulence to promote adaptation to the host. Toxins 11(3), 135. Details PubMed Open Access PDF Supplement

Allert S*, Förster TM*, Svensson CM, Richardson JP, Pawlik T, Hebecker B, Rudolphi S, Juraschitz M, Schaller M, Blagojevic M, Morschhäuser J, Figge MT, Jacobsen ID, Naglik JR, Kasper L, Mogavero S, Hube B; *authors contributed equally (2018) Candida albicans-induced epithelial damage mediates translocation through intestinal barriers. mBio 9(3), e00915-18. Details PubMed Open Access

Cseresnyes Z*, Kraibooj K*, Figge MT, *authors contributed equally (2018) Hessian-based quantitative image analysis of host- pathogen confrontation assays. Cytometry A 93(3), 346-356. Details PubMed Open Access PDF

Dasari P, Shopova IA, Stroe M, Wartenberg D, Dahse HM, Beyersdorf N, Hortschansky P, Dietrich S, Cseresnyés Z, Figge MT, Westermann M, Skerka C, Brakhage AA, Zipfel PF (2018) Aspf2 from Aspergillus fumigatus recruits human immune regulators for immune evasion and cell damage. Front Immunol 9, 1635. Details PubMed Open Access PDF Supplement

Dennhardt S, Pirschel W, Wissuwa B, Daniel C, Gunzer F, Lindig S, Medyukhina A, Kiehntopf M, Rudolph WW, Zipfel PF, Gunzer M, Figge MT, Amman K, Coldewey S (2018) Modeling hemolytic-uremic syndrome: In-depth characterization of distinct murine models reflecting different features of human disease. Front Immunol 9, 1459. Details PubMed Open Access PDF Supplement

Dudeck J*, Medyukhina A*, Figge MT**, Dudeck A**; *authors contributed equally; **corresponding authors, authors contributed equally (2018) Waffenübergabe im Immunsystem. Laborjournal 4, 40-43. (Review) Details PDF

Figge MT (2018) Quantitative bioimage analysis of cell characteristics. Cytometry A 93(3), 278-280. (Review) Details PubMed Open Access PDF

Figge MT (2018) Drops of blood in focus. LICHTGEDANKEN - The Magazine of the Friedrich Schiller University 3, 26-29. (Review) Details Open Access PDF

Meinel C, Spartà G, Dahse HM, Hörhold F, König R, Westermann M, Cseresnyés Z, Coldewey SM, Figge MT, Hammerschmidt S, Skerka C, Zipfel PF (2018) Streptococcus pneumoniae from patients with hemolytic uremic syndrome binds human plasminogen via the surface protein PspC and uses plasmin to damage human endothelial cells. J Infect Dis 217(3), 358-370. Details PubMed Open Access

Prauße MTE, Lehnert T, Timme S, Hünniger K, Leonhardt I, Kurzai O, Figge MT (2018) Predictive virtual infection modeling of fungal immune evasion in human whole blood. Front Immunol 9, 560. Details PubMed Open Access PDF Supplement

Schaarschmidt B, Vlaic S, Medyukhina A, Neugebauer S, Nietzsche S, Gonnert FA, Rödel J, Singer M, Kiehntopf M, Figge MT, Jacobsen ID, Bauer M, Press AT (2018) Molecular signatures of liver dysfunction are distinct in fungal and bacterial infections in mice. Theranostics 8(14), 3766-3780. Details PubMed Open Access PDF

Svensson CM, Medyukhina A, Belyaev I, Al-Zaben N, Figge MT (2018) Untangling cell tracks: Quantifying cell migration by time lapse image data analysis. Cytometry A 93(3), 357-370. Details PubMed Open Access PDF

Timme S, Lehnert T, Prauße MTE, Hünniger K, Leonhardt I, Kurzai O, Figge MT (2018) Quantitative simulations predict treatment strategies against fungal infections in virtual neutropenic patients. Front Immunol 9, 667. Details PubMed Open Access PDF Supplement

Brandes S, Dietrich S, Hünniger K, Kurzai O, Figge MT (2017) Migration and interaction tracking for quantitative analysis of phagocyte-pathogen confrontation assays. Medical Image Analysis 36, 172-183. Details PubMed Open Access PDF

Dudeck J*, Medyukhina A*, Froebel J, Svensson CM, Kotrba J, Gerlach M, Gradtke AC, Schröder B, Speier S, Figge MT**, Dudeck A**; *authors contributed equally; **corresponding authors, authors contributed equally (2017) Mast cells acquire MHCII from dendritic cells during skin inflammation. J Exp Med 214(12), 3791-3811. Details PubMed

Figge MT (2017) Systems Biology of Infection. In: NOVA ACTA LEOPOLDINA (ed.) Crossing Boundaries in Science. Documentation of the Workshop of the German National Academy of Sciences Leopoldina, Weimar, 06/30/2016-07/02/2016, 419, pp. 45-51.Wissenschaftliche Verlagsgesellschaft Stuttgart, Halle (Saale). ISBN: 978-3-8047-3758. (Review) Details Open Access PDF

Hoffmann B*, Svensson C-M*, Straßburger M, Gebser B, Irmler IM, Kamradt T, Saluz HP, Figge MT, *authors contributed equally (2017) Automated quantification of early bone alterations and pathological bone turnover in experimental arthritis by in vivo PET/CT imaging. Sci Rep 7, 2217. Details PubMed Open Access PDF

Klingberg A, Hasenberg A, Ludwig-Portugall I, Medyukhina A, Männ L, Brenzel A, Engel DR, Figge MT, Kurts C, Gunzer M (2017) Fully automated evaluation of total glomerular number and capillary tuft size in murine nephritic kidneys using lightsheet microscopy. J Am Soc Nephrol 28(2), 452-459. Details PubMed

Lehnert T, Figge MT (2017) Dimensionality of motion and binding valency govern receptor-ligand kinetics as revealed by agent-based modeling. Front Immunol 8, 1692. Details PubMed Open Access PDF Supplement

Svensson C-M, Bondoc K G, Pohnert G, Figge MT (2017) Segmentation of clusters by template rotation expectation maximization. Comput Vis Image Underst 152, 64-72. Details Open Access

Svensson CM*, Hoffmann B*, Irmler I, Straßburger M, Figge MT**, Saluz HP**; *authors contributed equally; **corresponding authors, authors contributed equally (2017) Quantification of arthritic bone degradation by analysis of 3D micro-computed tomography data. Sci Rep 7, 44434. Details PubMed Open Access PDF Supplement

Buhlmann D*, Eberhardt HU*, Medyukhina A, Prodinger WM, Figge MT, Zipfel PF, Skerka C *authors contributed equally (2016) FHR3 Blocks C3d-Mediated Coactivation of Human B Cells. J Immunol 197(2), 620-629. Details PubMed

Pollmächer J, Timme S, Schuster S, Brakhage AA, Zipfel PF, Figge MT (2016) Deciphering the counterplay of Aspergillus fumigatus infection and host inflammation by evolutionary games on graphs. Sci Rep 6, 27807. Details PubMed Open Access PDF Supplement

Brandes S, Mokhtari Z, Essig F, Hünniger K, Kurzai O, Figge MT (2015) Automated segmentation and tracking of non-rigid objects in time-lapse microscopy videos of polymorphonuclear neutrophils. Medical Image Analysis 20(1), 34-51. Details PubMed

Duggan S, Essig F, Hünniger K, Mokhtari Z, Bauer L, Lehnert T, Brandes S, Häder A, Jacobsen ID, Martin R, Figge MT, Kurzai O (2015) Neutrophil activation by Candida glabrata but not Candida albicans promotes fungal uptake by monocytes. Cell Microbiol 17(9), 1259-1276. Details PubMed

Figge MT, (2015) Image-based Systems Biology: what you get is more than you can see. G.I.T. Laboratory Journal Europe 19, 13-15. Details Open Access

Figge MT, Murphy RF (2015) Image-based Systems Biology. Cytometry A 87(6), 459-461. Details PubMed

Hünniger K, Bieber K, Martin R, Lehnert T, Figge MT, Löffler J, Guo R, Riedemann N, Kurzai O (2015) A second stimulus required for enhanced antifungal activity of human neutrophils in blood is provided by anaphylatoxin C5a. The Journal of Immunology 194(3), 1199-1210. Details PubMed

Kraibooj K*, Schoeler H*, Svensson C-M, Brakhage AA, Figge MT (2015) Automated quantification of the phagocytosis of Aspergillus fumigatus conidia by a novel image analysis algorithm. Frontiers in Microbiology 6(549), *authors contributed equally. Details PubMed Open Access

Lehnert T*, Timme S*, Pollmächer J, Hünniger K, Kurzai O, Figge MT (2015) Bottom-up modeling approach for the quantitative estimation of parameters in pathogen-host interactions. Frontiers in Microbiology 6(608), *authors contributed equally. Details PubMed Open Access

Mahler L, Tovar M, Weber T, Brandes S, Rudolph MM, Ehgartner J, Mayr T, Figge MT, Roth M, Zang E (2015) Enhanced and homogeneous oxygen availability during incubation of microfluidic droplets. RSC Advances 5, 101871-101878. Details Open Access PDF Supplement

Mattern DJ, Schoeler H, Weber J, Novohradská S, Kraibooj K, Dahse HM, Hillmann F, Valiante V, Figge MT, Brakhage AA (2015) Identification of the antiphagocytic trypacidin gene cluster in the human-pathogenic fungus Aspergillus fumigatus. Applied Microbiology and Biotechnology 99(23), 10151-10161. Details PubMed

Medyukhina A, Timme S, Mokhtari Z, Figge MT (2015) Image-based Systems Biology of Infection. Cytometry A 87(6), 462-470. Details PubMed

Mokhtari Z*, Mech F*, Zehentmeier S, Hauser AE, Figge MT (2015) Quantitative image analysis of cell colocalization in murine bone marrow. Cytometry A 87(6), 503-512, *authors contributed equally. Details PubMed

Pollmächer J, Figge MT (2015) Deciphering chemokine properties by a hybrid agent-based model of Aspergillus fumigatus infection in human alveoli. Frontiers in Microbiology 6(503), Details PubMed Open Access

Svensson C-M, Hübler R, Figge MT (2015) Automated classification of circulating tumor cells and the impact of inter-observer variability on classifier training and performance. Journal of Immunology Research 2015(Article ID 573165), 9. Details PubMed Open Access

Hünniger K*, Lehnert T*, Bieber K, Martin R, Figge MT⁺, Kurzai O⁺ (2014) A virtual infection model quantifies innate effector mechanisms and Candida albicans immune escape in human blood. PLOS Comput Biol 10(2), e1003479, */⁺authors contributed equally. Details PubMed Open Access

Irmler IM, Gebhardt P, Hoffmann B, Opfermann T, Figge MT, Saluz HP, Kamradt T (2014) 18 F-Fluoride positron emission tomography/computed tomography for noninvasive in vivo quantification of pathophysiological bone metabolism in experimental murine arthritis. Arthritis Res Ther 16(4), R155. Details PubMed Open Access

Kraibooj K*, Park HR*, Dahse HM, Skerka C, Voigt K⁺, Figge MT⁺ (2014) Virulent strain of Lichtheimia corymbifera shows increased phagocytosis by macrophages as revealed by automated microscopy image analysis. Mycoses 57(Suppl. 3), 56-66, */⁺authors contributed equally. Details PubMed Open Access

Mech F, Wilson D, Lehnert T, Hube B, Figge MT (2014) Epithelial invasion outcompetes hypha development during Candida albicans infection as revealed by an image-based systems biology approach. Cytometry A 85(2), 126-139. Details PubMed

Pollmächer J, Figge MT (2014) Agent-based model of human alveoli predicts chemotactic signaling by epithelial cells during early Aspergillus fumigatus infection. PLOS ONE 9(10), e111630. Details PubMed Open Access

Svensson C-M, Krusekopf S, Lücke J, Figge MT (2014) Automated detection of circulating tumor cells with naive Bayesian classifiers. Cytometry A 85(6), 501-511. Details PubMed

Coelho FM, Natale D, Soriano SF, Hons M, Swoger J, Mayer J, Danuser R, Scandella E, Pieczyk M, Zerwes HG, Junt T, Sailer AW, Ludewig B, Sharpe J, Figge MT, Stein JV (2013) Naive B-cell trafficking is shaped by local chemokine availability and LFA-1-independent stromal interactions. Blood 121(20), 4101-4109. Details PubMed

Figge MT, Osiewacz HD, Reichert AS (2013) Quality control of mitochondria during aging: is there a good and a bad side of mitochondrial dynamics? Bioessays 35(4), 314-322. Details PubMed

Mokhtari Z, Mech F, Zitzmann C, Hasenberg M, Gunzer M, Figge MT (2013) Automated characterization and parameter-free classification of cell tracks based on local migration behavior. PLOS ONE 8(12), e80808. Details PubMed Open Access

Zang E*, Brandes S*, Tovar M, Martin K, Mech F, Horbert P, Henkel T, Figge MT, Roth M (2013) Real-time image processing for label-free enrichment of Actinobacteria cultivated in picolitre droplets. Lab Chip 13(18), 3707-3713, *authors contributed equally. Details PubMed Open Access

Zhang Y, Meyer-Hermann M, George LA, Figge MT, Khan M, Goodall M, Young SP, Reynolds A, Falciani F, Waisman A, Notley CA, Ehrenstein MR, Kosco-Vilbois M, Toellner KM (2013) Germinal center B cells govern their own fate via antibody feedback. J Exp Med 210(3), 457-464. Details PubMed Open Access

Figge MT, Reichert AS, Meyer-Hermann M, Osiewacz HD (2012) Deceleration of fusion-fission cycles improves mitochondrial quality control during aging. PLOS Comput Biol 8(6), e1002576. Details PubMed Open Access

Guthke R, Linde J, Mech F, Figge MT (2012) Systems biology of microbial infection. Front Microbiol 3, 328. Details PubMed Open Access

Mech F, Figge MT (2012) Image-based systems biology: A quantitative approach to elucidate the kinetics of fungal morphologies and virulence. In: Highlight Papers of the German Conference on Bioinformatics 2012 German Conference on Bioinformatics, Jena, GCB. Details PDF

Tokarski C, Hummert S, Mech F, Figge MT, Germerodt S, Schroeter A, Schuster S (2012) Agent-based modeling approach of immune defense against spores of opportunistic human pathogenic fungi. Front Microbiol 3, 129. Details PubMed Open Access

Figge MT, Meyer-Hermann M (2011) Modelling Intravital Two-Photon Data of Lymphocyte Migration and Interaction In: Molina-París C, Lythe G (eds.) Mathematical Models and Immune Cell Biology pp. 121-139. Springer, Heidelberg. ISBN: 978-1-4419-7724. Details

Mech F*, Thywissen A*, Guthke R, Brakhage AA, Figge MT (2011) Automated image analysis of the host-pathogen interaction between phagocytes and Aspergillus fumigatus. PLOS ONE 6(5), e19591, *authors contributed equally. Details PubMed Open Access

Fatehi H, Meyer-Hermann M, Figge MT (2010) Modelling cellular aggregation induced by chemotaxis and phototaxis. Math Med Biol 27(4), 373-384. Details PubMed

Garin A, Meyer-Hermann M, Contie M, Figge MT, Buatois V, Gunzer M, Toellner KM, Elson G, Kosco-Vilbois MH (2010) Toll-like receptor 4 signaling by follicular dendritic cells is pivotal for germinal center onset and affinity maturation. Immunity 33(1), 84-95. Details PubMed Open Access

Figge MT (2009) Optimization of immunoglobulin substitution therapy by a stochastic immune response model. PLOS ONE 4(5), e5685. Details PubMed Open Access

Figge MT, Meyer-Hermann M (2009) Modeling receptor-ligand binding kinetics in immunological synapse formation. The European Physical Journal D 51(1), 153-160. Details

Meyer-Hermann M, Figge MT, Straub RH (2009) Mathematical modeling of the circadian rhythm of key neuroendocrine-immune system players in rheumatoid arthritis: a systems biology approach. Arthritis Rheum 60(9), 2585-2594. Details PubMed Open Access

Meyer-Hermann M, Figge MT, Toellner KM (2009) Germinal centres seen through the mathematical eye: B-cell models on the catwalk. Trends Immunol 30(4), 157-164. Details PubMed

Figge MT, Garin A, Gunzer M, Kosco-Vilbois M, Toellner KM, Meyer-Hermann M (2008) Deriving a germinal center lymphocyte migration model from two-photon data. J Exp Med 205(13), 3019-3029. Details PubMed Open Access

Figge MT, Meyer-Hermann M (2006) Geometrically repatterned immunological synapses uncover formation mechanisms. PLOS Comput Biol 2(11), e171. Details PubMed Open Access

Michielsen K, Figge MT, De Raedt H, De Hossen JTM (2004) Molecular dynamics simulation of nanoindentation In: Computer simulation studies incondensed-matter physics XVI pp. 250-255.Springer-Verlag, Berlin Heidelberg. ISBN: 978-3-642-63923. Details

De Raedt H, Kole JS, Michielsen K, Figge MT (2003) Unified framework for numerical methods to solve the time-dependent Maxwell equations. Computer Physics Communication 156, 43-61. Details PDF

De Raedt H, Michielsen K, Kole JS, Figge MT (2003) Chebyshev method to solve the time-dependent Maxwell equations. In: Computer simulation studies in condensed-matter physics XV, pp. 211-215.Springer-Verlag Berlin Heidelberg. Details

De Raedt H, Michielsen K, Kole JS, Figge MT (2003) One-step finite-difference time-domain algorithm to solve the Maxwell equations. Phys Rev E Stat Nonlin Soft Matter Phys 67(5 Pt 2), 056706. Details PubMed

De Raedt H, Michielsen K, Kole JS, Figge MT (2003) Solving the Maxwell equations by the Chebyshev method: a one-step finite-difference time-domain algorithm. IEEE Transactions on Antennas and Propagation 51, 3155-3160. Details PDF

Figge MT, Michielsen K, De Raedt H, De Hosson JTM, van der Giessen E (2003) Molecular dynamics simulation of dislocation dynamics during nanoindentation. In: Advances in Computational & Experimental Engeneering & Sciences International Conference ICCES 2003, Tech Science Press. Details

Kole JS, Figge MT, De Raedt H (2003) Solving the time-dependent Maxwell equations by unconditionally stable algorithms. In: Computer simulation studies in condensed-matter physics XV pp. 205-210.Springer-Verlag Berlin Heidelberg. Details

Figge MT (2002) Statistical model for receptor-ligand binding thermodynamics. Phys Rev E Stat Nonlin Soft Matter Phys 66(6 Pt 1), 061901. Details PubMed

Figge MT, Mostovoy M, Knoester J (2002) Peierls instability due to the interaction of electrons with both acoustic and optical phonons in metallic carbon nanotubes. Physical Review B 65(12), 125416. Details

Kole JS, Figge MT, and De Raedt H (2002) New unconditionally stable algorithms to solve the time-dependent Maxwell equations. Springer Verlag Lecture Notes in Computer Science (LNCS) 2329, 803. Details

Kole JS, Figge MT, De Raedt H (2002) Higher-order unconditionally stable algorithms to solve the time-dependent Maxwell equations. Phys Rev E Stat Nonlin Soft Matter Phys 65(6 Pt 2), 066705. Details PubMed

Figge MT, Mostovoy M, Knoester J (2001) Peierls transition with acoustic phonons and solitwistons in carbon nanotubes. Phys Rev Lett 86(20), 4572-4575. Details PubMed

Kole JS, Figge MT, De Raedt H (2001) Unconditionally stable algorithms to solve the time-dependent Maxwell equations. Phys Rev E Stat Nonlin Soft Matter Phys 64(6 Pt 2), 066705. Details PubMed

Figge MT (2000) Disorder and interchain interactions in Peierls systems. In: PhD thesis, University of Groningen. ISBN: ISBN 90-367-127. Details PDF

Figge MT, Mostovoy M, Knoester J (1999) Disorder-induced neutral solitons in degenerate ground state polymers. Synthetic Metals 101(1-3), 388-389. Details

Figge MT, Mostovoy M, Knoester J (1999) Magnetic susceptibility due to disorder-induced neutral solitons in interacting polymer chains. Physical Review B 59(21), 13882-13891. Details Open Access PDF

Mostovoy M, Figge MT, Knoester J (1998) Density of neutral solitons in weakly disordered Peierls chains. Physical Review B 57(5), 2861-2871. Details Open Access PDF

Mostovoy M, Figge MT, Knoester J (1998) Critical temperature and density of spin flips in the anisotropic random-field Ising model. Physical Review B 58(5), 2626-2634. Details Open Access PDF

Mostovoy M, Figge MT, Knoester J (1997) Disorder-induced solitons in conjugated polymers. Europhysics Letters 38(9), 687-692. Details