Prof. Dr. Christine Beemelmanns

Chemical Biology of Microbe-Host Interactions · Head +49 3641 532-1525 christine.beemelmanns@leibniz-hki.de

Curriculum vitae

Main Research Areas

Isolation and determination of the structure of signal molecules and antimicrobial natural products
Characterisation of interactions between microbes and eucaryotes
Total synthesis of natural products and chemical derivatisation

Professional Career

since 01/2022	Professor of Biochemistry of Microbial Metabolism at the University of Leipzig
Since 12/2013	Junior group head at the Leibniz-Institute for Natural Product Research and Infection Biology - Hans-Knöll-Institute, Jena, chemical biology of microbe-host-interactions
2011-2013	Postdoc at the Harvard Medical School, Harvard University, supervisor: Prof. J. Clardy, BCMP, Department of Biomolecular Chemistry and Molecular Pharmacology
2010-2011	Postdoc at the Tokyo Institute of Technology, chemical faculty (Tokyo, Japan) supervisor: Prof. K. Suzuki
2010	Dr. rer. nat. in chemistry, summa cum laude, Freie Universität Berlin
2007-2010	PhD dissertation, organic chemistry instructed by Prof. H.-U. Reißig at the Freie Universität Berlin (Germany)
2006-2007	Research period at the RIKEN, chemistry, in the working group of Prof. M. Sodeoka (Japan)
2001-2006	Studies in chemistry, diploma at the RWTH Aachen (Germany)

Awards · Appointments · Scientific Activities

2021	Nachwuchswissenschaftler-Preise für Naturstoffforschung
2020	Dozentenpreis des Fonds der Chemischen Industrie
2020	Visiting Professor in Madison Wisconsin USA
2019-2024	ERC Starting GRant MORPHEUS
2014-2015	Postdoc fellowship from the Daimler and Benz Foundation and the Reinhard Frank Foundation
Since 2014	Membership VAAM, FEMS and IUMS
Since 2014	Membership Dechema
Since 2014	Membership National Research Foundation of Korea
2011-2013	Postdoc fellowship from the Leopoldina Nationale Akademie der Wissenschaften; Postdoc fellowship from the DFG rejected
2011	Ernst-Reuter-Award of the Freie Universität Berlin; Ernst-Reuter-Gesellschaft der Freunde, Förderer und Ehemaligen der Freien Universität Berlin (Berlin, Germany)
2010-2011	Postdoc fellowship from the DAAD
Since 2010	Member of the commission, Studienstiftung des deutschen Volkes
2007-2010	Networking fellowship for doctoral researchers at the Studienstiftung des deutschen Volkes
2007-2009	Doctoral fellowship funded by the Verband Chemischen Industrie (VCI)
2006	Springorum commemorative coin from the RWTH Aachen (Aachen, Germany)
2006	Procter and Gamble award, expert group chemistry at the RWTH Aachen
2006-2007	RIKEN fellowship from the Studienstiftung des deutschen Volkes
2004-2006	Studies in chemistry: fellowship from the Studienstiftung des deutschen Volkes
Since 2003	Member of the GDCH
2003	Chemical award from the faculty for mathematics, informatics, natural sciences, RWTH Aachen
2003	Schöneborn award from the Gesellschaft der Freunde und Förderer der RWTH Aachen e.V., RWTH Aachen (Aachen, Germany)

Publications

Schalk F, Gostinčar C, Kreuzenbeck NB, Conlon BH, Sommerwerk E, Rabe P, Burkhardt I, Krüger T, Kniemeyer O, Brakhage AA, Gunde-Cimerman N, de Beer ZW, Dickschat JS, Poulsen M, Beemelmanns C (2021) The termite fungal cultivar Termitomyces combines diverse enzymes and oxidative reactions for plant biomass conversion. mBio 12(3), e0355120.

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Schmidt S, Kildgaard S, Guo H, Beemelmanns C, Poulsen M (2021) The chemical ecology of the fungus-farming termite symbiosis. Nat Prod Rep 39(2), 231-248. (Review)

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Schorn MA, Verhoeven S, Ridder L, Huber F, Acharya DD, Aksenov AA, Aleti G, Moghaddam JA, Aron AT, Aziz S, Bauermeister A, Bauman KD, Baunach M, Beemelmanns C, Beman JM, Berlanga-Clavero MV, Blacutt AA, Bode HB, Boullie A, Brejnrod A, Bugni TS, Calteau A, Cao L, Carrión VJ, Castelo-Branco R, Chanana S, Chase AB, Chevrette MG, Costa-Lotufo LV, Crawford JM, Currie CR, Cuypers B, Dang T, de Rond T, Demko AM, Dittmann E, Du C, Drozd C, Dujardin JC, Dutton RJ, Edlund A, Fewer DP, Garg N, Gauglitz JM, Gentry EC, Gerwick L, Glukhov E, Gross H, Gugger M, Guillén Matus DG, Helfrich EJN, Hempel BF, Hur JS, Iorio M, Jensen PR, Kang KB, Kaysser L, Kelleher NL, Kim CS, Kim KH, Koester I, König GM, Leao T, Lee SR, Lee YY, Li X, Little JC, Maloney KN, Männle D, Martin HC, McAvoy AC, Metcalf WW, Mohimani H, Molina-Santiago C, Moore BS, Mullowney MW, Muskat M, Nothias LF, O'Neill EC, Parkinson EI, Petras D, Piel J, Pierce EC, Pires K, Reher R, Romero D, Roper MC, Rust M, Saad H, Saenz C, Sanchez LM, Sørensen SJ, Sosio M, Süssmuth RD, Sweeney D, Tahlan K, Thomson RJ, Tobias NJ, Trindade-Silva AE, van Wezel GP, Wang M, Weldon KC, Zhang F, Ziemert N, Duncan KR, Crüsemann M, Rogers S, Dorrestein PC, Medema MH, van der Hooft JJJ (2021) A community resource for paired genomic and metabolomic data mining. Nat Chem Biol 17(4), 363-368.

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Um S, Guo H, Thiengmag S, Benndorf R, Murphy R, Rischer M, Braga D, Poulsen M, de Beer ZW, Lackner G, Beemelmanns C (2021) Comparative genomic and metabolic analysis of Streptomyces sp. RB110 morphotypes illuminates genomic rearrangements and formation of a new 46-membered antimicrobial macrolide. ACS Chem Biol 16(8), 1482-1492.

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Um S, Seibel E, Schalk F, Balluf S, Beemelmanns C (2021) Targeted isolation of saalfelduracin B-D from Amycolatopsis saalfeldensis using LC-MS/MS-based molecular networking. J Nat Prod 84(4), 1002-1011.

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Vidkjær NH, Schmidt S, Hu H, Bodawatta KH, Beemelmanns C, Poulsen M (2021) Species- and caste-specific gut metabolomes in fungus-farming termites. Metabolites 11(2), 839.

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Benndorf R, Martin K, Küfner M, de Beer ZW, Vollmers J, Kaster AK, Beemelmanns C (2020) Actinomadura rubteroloni sp. nov. and Actinomadura macrotermitis sp. nov., isolated from the gut of the fungus growing-termite Macrotermes natalensis. Int J Syst Evol Microbiol 70(10), 5255-5262.

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Benndorf R, Schwitalla JW, Martin K, de Beer ZW, Vollmers J, Kaster AK, Poulsen M, Beemelmanns C (2020) Nocardia macrotermitis sp. nov. and Nocardia aurantia sp. nov., isolated from the gut of the fungus-growing termite Macrotermes natalensis. Int J Syst Evol Microbiol 70(10), 5226-5234.

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Ghodsi Z, Kalbassi MR, Farzaneh P, Mobarez AM, Beemelmanns C, Amiri Moghaddam J (2020) Immunomodulatory function of antimicrobial peptide Ec-Hepcidin1 modulates the induction of inflammatory gene expression in primary cells of caspian trout (Salmo trutta caspius Kessler, 1877). Fish Shellfish Immunol 104, 55-61.

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Guo H, Schwitalla JW, Benndorf R, Baunach M, Steinbeck C, Görls H, de Beer ZW, Regestein L, Beemelmanns C (2020) Gene cluster activation in a bacterial symbiont leads to halogenated angucyclic maduralactomycins and spirocyclic actinospirols. Org Lett 22(7), 2634-2638.

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