Publications

Bredy F, Ishida K, Hertweck C (2022) A Type III Polyketide Synthase Specific for Sporulating Negativicutes is Responsible for Alkylpyrone Biosynthesis. Chembiochem ,
Kim HJ, Ishida K, Hertweck C (2022) Thiotemplated Biosynthesis of Bacterial Polyyne Fatty Acids by a Designated Desaturase Triad. Chembiochem ,
Kim HJ, Ishida K, Ishida-Ito M, Hertweck C (2022) Sequential allylic alcohol formation by a multifunctional cytochrome P450 monooxygenase with rare redox partners. Angew Chem Int Ed 61(26), e202203264.
Krumbholz J, Ishida K, Baunach M, Teikari JE, Rose MM, Sasso S, Hertweck C, Dittmann E (2022) Deciphering chemical mediators regulating specialized metabolism in a symbiotic cyanobacterium. Angew Chem Int Ed 61(26), e202204545.
Trottmann F, Ishida K, Ishida-Ito M, Kries H, Groll M, Hertweck C (2022) Pathogenic bacteria remodel central metabolic enzyme to build a cyclopropanol warhead. Nat Chem 14(8), 884-890.
Ishida K, Shabuer G, Schieferdecker S, Pidot SJ, Stinear TP, Knuepfer U, Cyrulies M, Hertweck C (2020) Oak-associated negativicute equipped with ancestral aromatic polyketide synthase produces antimycobacterial dendrubins. Chem Eur J 26(58), 13147-13151.
Neuwirth T, Letzel AC, Tank C, Ishida K, Cyrulies M, Schmölz L, Lorkowski S, Hertweck C (2020) Induced production, synthesis and immunomodulatory action of clostrisulfone, a diarylsulfone from Clostridium acetobutylicum. Chemistry 26(68), 15855-15858.
Niehs SP, Kumpfmüller J, Dose B, Little RF, Ishida K, Florez LV, Kaltenpoth M, Hertweck C (2020) Insect-associated bacteria assemble the antifungal butenolide gladiofungin by non-canonical polyketide chain termination. Angew Chem Int Ed 59(51), 23122-23126.
Trottmann F, Ishida K, Franke J, Stanišić A, Ishida-Ito M, Kries H, Pohnert G, Hertweck C (2020) Sulfonium acids loaded onto an unusual thiotemplate assembly line construct the cyclopropanol warhead of a Burkholderia virulence factor. Angew Chem Int Ed 59(32), 13511-13515.
Bratovanov EV, Ishida K, Heinze B, Pidot SJ, Stinear TP, Hegemann JD, Marahiel MA, Hertweck C (2019) Genome mining and heterologous expression reveal two distinct families of lasso peptides highly conserved in endofungal bacteria. ACS Chem Biol 15(5), 1169-1176.