Curriculum vitae

Professional Career

 

since 2016 Junior Group Leader, Leibniz Institute for Natural Product Research and Infection Biology (Hans-Knöll-Institute), Jena
2014-2016 Postdoc, John Innes Centre, Norwich (UK), with Prof. Sarah E. O'Connor
2009-2014 PhD "Tailor-made biocatalysts by enzyme design, redesign, and directed evolution" at ETH Zurich with Prof. Donald Hilvert
2007-2009 MSc in Chemistry, ETH Zurich
2006-2007 BSc in Biochemistry, University of Geneva
2003-2006 Studies of Biochemistry, University of Jena
2002 Abitur at the Gymnasium Heide-Ost
Awards · Appointments · Scientific Activities
2021 Max Buchner Fellowship, DECHEMA
2020 Medac Research Prize
2019 FCI material cost allowances
2017-2019 Fellowship of the Daimler and Benz Foundation
2015-2016 Marie Skłodowska-Curie postdoctoral fellowship (H2020), project 658155
2015 Friedrich-Weygang-Preis, awarded by the Max-Bergmann-Kreis
2015 ETH Medal for the PhD thesis
2014-2015 Early Postdoc.Mobility fellowship of the Swiss National Science Foundation (SNSF)
2011-2014 PhD Fellowship of the Stipendienfonds der Schweizerischen Chemischen Industrie (SSCI)
2010-2012 PhD Fellowship of the German Academic Scholarship Foundation
2008-2009 Oskar Jeger Fellowship for master studies (ETH Zurich)
2008 Novartis Master Fellowship
2007-2009 DAAD grant for foreign studies
2005-2009 Fellowship of the German Academic Scholarship Foundation

Publications

Stanišić A, Hüsken A, Stephan P, Niquille DL, Reinstein J, Kries H (2021) Engineered nonribosomal peptide synthetase shows opposite amino acid loading and condensation specificity. ACS Catal 11(14), 8692-8700.
Huang HM, Stephan P, Kries H (2020) Engineering DNA-templated nonribosomal peptide synthesis. Cell Chem Biol S2451-9456(20), 30433-5.
Kries H, Bloch J, Bunzel HA, Pinkas DM, Hilvert D (2020) Contribution of oxyanion stabilization to Kemp eliminase efficiency. ACS Catal 10(8), 4460-4464.
Trottmann F, Ishida K, Franke J, Stanišić A, Ishida-Ito M, Kries H, Pohnert G, Hertweck C (2020) Sulfonium acids loaded onto an unusual thiotemplate assembly line construct the cyclopropanol warhead of a Burkholderia virulence factor. Angew Chem Int Ed 59(32), 13511-13515.
Wurlitzer J, Stanišić A, Wasmuth I, Jungmann S, Fischer D, Kries H, Gressler M (2020) Bacterial-like nonribosomal peptide synthetases produce cyclopeptides in the zygomycetous fungus Mortierella alpina. Appl Env Microbiol 87(3), e02051-20.
Bunzel HA, Kries H, Marchetti L, Zeymer C, Mittl P, Mulholland AJ, Hilvert D (2019) Emergence of a negative activation heat capacity during evolution of a designed enzyme. J Am Chem Soc 141(30), 11745-11748.
Götze S, Arp J, Lackner G, Zhang S, Kries H, Klapper M, García-Altares M, Willing K, Günther M, Stallforth P (2019) Structure elucidation of the syringafactin lipopeptides provides insight in the evolution of nonribosomal peptide synthetases. Chem Sci 10(48), 10979-10990.
Huang HM, Kries H (2019) Unleashing the potential of ribosomal and nonribosomal peptide biosynthesis. Biochemistry 58(2), 73-74. (Review)
Lichman B, O'Connor SE, Kries H (2019) Biocatalytic strategies towards [4+2] cycloadditions. Chemistry 25(28), 6864-6877. (Review)
Stanišić A, Hüsken A, Kries, H (2019) HAMA: A multiplexed LC-MS/MS assay for specificity profiling of adenylate-forming enzymes. Chem Sci 10(44), 10395-10399.