Publications

Fiedler J, Trottmann F, Ishida K, Mie II, Hertweck C (2024) Direct a-hydroxy acid loading onto a bacterial thiotemplate assembly line via a multienzyme gateway. Angew Chem Int Ed Engl [Epub ahead of print]
Haensch VG, Hertweck C (2024) Photosensitizers enable the formation of biphenyls with UV-LEDs and sunlight. Chemistry , e202400605.
Hoffmann A, Steffens U, Maček B, Franz-Wachtel M, Nieselt K, Harbig TA, Scherlach K, Hertweck C, Sahl H-G, Bierbaum G (2024) The unusual mode of action of the polyketide glycoside antibiotic cervimycin C. mSphere , e0076423.
Little RF, Trottmann F, Hashizume H, Preissler M, Unger S, Sawa R, Kries H, Pidot S, Igarashi M, Hertweck C (2024) Analysis of the valgamicin biosynthetic pathway reveals a general mechanism for cyclopropanol formation across diverse natural product scaffolds. ACS Chem Biol 19(3), 660-668.
Richter I, Hasan M, Kramer JW, Wein P, Krabbe J, Woitas KP, Stinear TP, Pidot SJ, Kloss F, Hertweck C, Lackner G (2024) Deazaflavin metabolite produced by endosymbiotic bacteria controls fungal host reproduction. ISME J , wrae074.
Roman D, Meisinger P, Guillonneau R, Peng CC, Peltner LK, Jordan PM, Haensch V, Götze S, Werz O, Hertweck C, Chen Y, Beemelmanns C (2024) Structure revision of a widespread marine sulfonolipid class based on isolation and total synthesis. Angew Chem Int Ed Engl [Epub ahead of print]
Büttner H, Hörl J, Krabbe J, Hertweck C (2023) Discovery and biosynthesis of anthrochelin, a growth-promoting metallophore of the human pathogen Luteibacter anthropi. Chembiochem 24(17), e202300322.
Büttner H, Pidot SJ, Scherlach K, Hertweck C (2023) Endofungal bacteria boost anthelminthic host protection with the biosurfactant symbiosin. Chem Sci 14(1), 103-112.
Dell M, Tran MA, Capper MJ, Sundaram S, Fiedler J, Koehnke J, Hellmich UA, Hertweck C (2023) Trapping of a polyketide synthase module after C-C bond formation reveals transient acyl carrier domain interactions. Angew Chem Int Ed Engl 63(9), e202315850.
Ehinger F, Niehs S, Dose B, Dell M, Krabbe J, Pidot SJ, Stinear TP, Scherlach K, Ross C, Lackner G, Hertweck C (2023) Analysis of rhizonin biosynthesis reveals origin of pharmacophoric furylalanine moieties in diverse cyclopeptides. Angew Chem Int Ed Engl 62(42), e202308540.