Publications

Lenz C, Dörner S, Trottmann F, Hertweck C, Sherwood A, Hoffmeister D (2022) Assessment of bioactivity-modulating pseudo-ring formation in psilocin and related tryptamines. ChemBioChem 23(13), e202200183.
Little R, Trottmann F, Preissler M, Hertweck C (2022) An intramodular thioesterase domain catalyses chain release in the biosynthesis of a cytotoxic virulence factor. RSC Chem Biol 3(9), 1121-1128.
Little RF, Hertweck C (2022) Chain release mechanisms in polyketide and non-ribosomal peptide biosynthesis. Nat Prod Rep 39(1), 163-205. (Review)
Michel M, Benítez-Buelga C, Calvo PA, Hanna BMF, Mortusewicz O, Masuyer G, Davies J, Wallner O, Sanjiv K, Albers JJ, Castañeda-Zegarra S, Jemth AS, Visnes T, Sastre-Perona A, Danda AN, Homan EJ, Marimuthu K, Zhenjun Z, Chi CN, Sarno A, Wiita E, von Nicolai C, Komor AJ, Rajagopal V, Müller S, Hank EC, Varga M, Scaletti ER, Pandey M, Karsten S, Haslene-Hox H, Loevenich S, Marttila P, Rasti A, Mamonov K, Ortis F, Schömberg F, Loseva O, Stewart J, D'Arcy-Evans N, Koolmeister T, Henriksson M, Michel D, de Ory A, Acero L, Calvete O, Scobie M, Hertweck C, Vilotijevic I, Kalderén C, Osorio A, Perona R, Stolz A, Stenmark P, Berglund UW, de Vega M, Helleday T (2022) Small-molecule activation of OGG1 increases oxidative DNA damage repair by gaining a new function. Science 376(6600), 1471-1476.
Morales-Amador A, Souto ML, Hertweck C, Fernández JJ, García-Altares M (2022) Rapid screening of polyol polyketides from marine Dinoflagellates. Anal Chem 94(41), 14205-14213.
Niehs S, Scherlach K, Dose B, Uzum Z, Stinear T, Pidot S, Hertweck C (2022) A highly conserved gene locus in endofungal bacteria codes for the biosynthesis of symbiosis-specific cyclopeptides. PNAS nexus 1(4), 152.
Pourmasoumi F,* De S,* Peng H, Trottmann F, Hertweck C, Kries H (2022) Proof-reading thioesterase boosts activity of engineered nonribosomal peptide synthetase. ACS Chem Biol 17(9), 2382-2388.
Richter I, Radosa S, Cseresnyés Z, Ferling I, Büttner H, Niehs SP, Gerst R, Figge MT, Hillmann F, Hertweck C (2022) Toxin-producing endosymbionts shield pathogenic fungus against micropredators. mBio 13(5), e0144022.
Sharma G, Islam ST, Rahi P, Silby MW, Giovannelli D, Welander PV, Ehling-Schulz M, Chaudhry V, Molloy E, Hertweck C, Mundra S, Kalia VC, Lal R, Singh Y, Ruby E, Weigel C, Kolter R (2022) Reply to Oren et al., "New phylum names harmonize prokaryotic nomenclature". mBio 13(5), e0232322. (Review)
Trottmann F, Ishida K, Ishida-Ito M, Kries H, Groll M, Hertweck C (2022) Pathogenic bacteria remodel central metabolic enzyme to build a cyclopropanol warhead. Nat Chem 14(8), 884-890.