Biomolecular Chemistry

Horch T, Molloy EM, Bredy F, Haensch VG, Scherlach K, Dunbar KL, Franke J, Hertweck C (2022) Alternative benzoxazole assembly discovered in anaerobic bacteria provides access to privileged heterocyclic scaffold. Angew Chem Int Ed 61(32), e202205409.

Janke RS, Kaftan F, Niehs SP, Scherlach K, Rodrigues A, Svatoš A, Hertweck C, Kaltenpoth M, Flórez LV (2022) Bacterial ectosymbionts in cuticular organs chemically protect a beetle during molting stages. ISME J 16(12), 2691-2701.

Kim HJ, Ishida K, Hertweck C (2022) Thiotemplated biosynthesis of bacterial polyyne fatty acids by a designated desaturase triad. ChemBioChem 23(21), e202200430.

Kim HJ, Ishida K, Ishida-Ito M, Hertweck C (2022) Sequential allylic alcohol formation by a multifunctional cytochrome P450 monooxygenase with rare redox partners. Angew Chem Int Ed 61(26), e202203264.

Klemm P, Solomun JI, Rodewald M, Kuchenbrod MT, Hänsch VG, Richter F, Popp J, Hertweck C, Hoeppener S, Bonduelle C, Lecommandoux S, Traeger A, Schubert S (2022) Efficient gene delivery of tailored amphiphilic polypeptides by polyplex surfing. Biomacromolecules 23(11), 4718-4733.

Krumbholz J, Ishida K, Baunach M, Teikari JE, Rose MM, Sasso S, Hertweck C, Dittmann E (2022) Deciphering chemical mediators regulating specialized metabolism in a symbiotic cyanobacterium. Angew Chem Int Ed 61(26), e202204545.

Lenz C, Dörner S, Trottmann F, Hertweck C, Sherwood A, Hoffmeister D (2022) Assessment of bioactivity-modulating pseudo-ring formation in psilocin and related tryptamines. ChemBioChem 23(13), e202200183.

Little R, Trottmann F, Preissler M, Hertweck C (2022) An intramodular thioesterase domain catalyses chain release in the biosynthesis of a cytotoxic virulence factor. RSC Chem Biol 3(9), 1121-1128.

Little RF, Hertweck C (2022) Chain release mechanisms in polyketide and non-ribosomal peptide biosynthesis. Nat Prod Rep 39(1), 163-205. (Review)

Michel M, Benítez-Buelga C, Calvo PA, Hanna BMF, Mortusewicz O, Masuyer G, Davies J, Wallner O, Sanjiv K, Albers JJ, Castañeda-Zegarra S, Jemth AS, Visnes T, Sastre-Perona A, Danda AN, Homan EJ, Marimuthu K, Zhenjun Z, Chi CN, Sarno A, Wiita E, von Nicolai C, Komor AJ, Rajagopal V, Müller S, Hank EC, Varga M, Scaletti ER, Pandey M, Karsten S, Haslene-Hox H, Loevenich S, Marttila P, Rasti A, Mamonov K, Ortis F, Schömberg F, Loseva O, Stewart J, D'Arcy-Evans N, Koolmeister T, Henriksson M, Michel D, de Ory A, Acero L, Calvete O, Scobie M, Hertweck C, Vilotijevic I, Kalderén C, Osorio A, Perona R, Stolz A, Stenmark P, Berglund UW, de Vega M, Helleday T (2022) Small-molecule activation of OGG1 increases oxidative DNA damage repair by gaining a new function. Science 376(6600), 1471-1476.