Biomolecular Chemistry

Schieferdecker S, Shabuer G, Knuepfer U, Hertweck C (2019) Clostrindolin is an antimycobacterial pyrone alkaloid from Clostridium beijerinckii. Org Biomol Chem 17(25), 6119-6121.

Schieferdecker S, Shabuer G, Letztel AC, Urbansky B, Ishida-Ito M, Ishida K, Cyrulies M, Dahse HM, Pidot S, Hertweck C (2019) Biosynthesis of diverse antimicrobial and antiproliferative acyloins in anaerobic bacteria. ACS Chem Biol 14(7), 1490-1497.

Trottmann F, Franke J, Ishida K, Garcia-Altares M, Hertweck C (2019) A pair of bacterial siderophores releases and traps an intercellular signal molecule: An unusual case of natural nitrone bioconjugation. Angew Chem Int Ed 58(1), 200-204.

Trottmann F, Franke J, Richter I, Ishida K, Cyrulies M, Dahse HM, Regestein L, Hertweck C (2019) Cyclopropanol warhead in malleicyprol confers virulence of human- and animal-pathogenic Burkholderia species. Angew Chem Int Ed 58(40), 14129-14133.

Arp J, Götze S, Mukherji R, Mattern DJ, Garcia-Altares M, Klapper M, Brock DA, Brakhage AA, Strassmann JE, Queller DC, Bardl B, Willing K, Peschel G, Stallforth P (2018) Synergistic activity of co-secreted natural products from amoebae-associated bacteria. Proc Natl Acad Sci USA 115(15), 3758-3763.

Dose B, Niehs SP, Scherlach K, Flórez LV, Kaltenpoth M, Hertweck C (2018) Unexpected bacterial origin of the antibiotic icosalide: Two-tailed depsipeptide assembly in multifarious Burkholderia symbionts. ACS Chem Biol 13(9), 2414-2420.

Dunbar KL, Büttner H, Molloy EM, Dell M, Kumpfmüller J, Hertweck C (2018) Genome editing reveals novel thiotemplated assembly of polythioamide antibiotics in anaerobic bacteria. Angew Chem Int Ed 57(43), 14080-14084.

Fischer J, Müller SY, Netzker T, Jäger N, Gacek-Matthews A, Scherlach K, Stroe MC, García-Altares M, Pezzini F, Schoeler H, Reichelt M, Gershenzon, Krespach MK, Shelest E, Schroeckh V, Valiante V, Heinzel T, Hertweck C, Strauss J, Brakhage AA (2018) Chromatin mapping identifies BasR, a key regulator of bacteria-triggered production of fungal secondary metabolites. eLife 7, e40969.

Flórez LV, Scherlach K, Miller IJ, Rodrigues A, Kwan JC, Hertweck C, Kaltenpoth M (2018) An antifungal polyketide associated with horizontally acquired genes supports symbiont-mediated defense in Lagria villosa beetles. Nat Commun 9(1), 2478.

Heimerl N, Hommel E, Westermann M, Meichsner D, Lohr M, Hertweck C, Grossman AR, Mittag M, Sasso S (2018) A giant type I polyketide synthase participates in zygospore maturation in Chlamydomonas reinhardtii. Plant J 95(2), 268-281.