Publications

Braga D, Last D, Hasan M, Guo H, Leichnitz D, Uzum Z, Richter I, Schalk F, Beemelmanns C, Hertweck C, Lackner G (2019) Metabolic pathway rerouting in Paraburkholderia rhizoxinica evolved long-overlooked derivatives of coenzyme F420. ACS Chem Biol 14(9), 2088-2094. Details PubMed PDF

Bratovanov EV, Ishida K, Heinze B, Pidot SJ, Stinear TP, Hegemann JD, Marahiel MA, Hertweck C (2019) Genome mining and heterologous expression reveal two distinct families of lasso peptides highly conserved in endofungal bacteria. ACS Chem Biol 15(5), 1169-1176. Details PubMed

Costa JH, Wassano CI, Angolini CFF, Scherlach K, Hertweck C, Pacheco Fill T (2019) Antifungal potential of secondary metabolites involved in the interaction between citrus pathogens. Sci Rep 9(1), 18647. Details PubMed Open Access PDF

Dörfer M, Heine D, König S, Gore S, Werz O, Hertweck C, Gressler M, Hoffmeister D (2019) Melleolides impact fungal translation via elongation factor 2. Org Biomol Chem 17(19), 4906-4916. Details PubMed

Dunbar KL, Dell M, Molloy EM, Kloss F, Hertweck C (2019) Reconstitution of iterative thioamidation in closthioamide biosynthesis reveals a novel nonribosomal peptide backbone-tailoring strategy. Angew Chem Int Ed 58(37), 13014-13018. Details PubMed Open Access PDF

Fischer D, Gessner G, Fill TP, Barnett R, Tron K, Dornblut K, Kloss F, Stallforth P, Hube B, Heinemann SH, Hertweck C, Scherlach K, Brunke S (2019) Disruption of membrane integrity by the bacteria-derived antifungal jagaricin. Antimicrob Agents Chemother 63(9), e00707-19. Details PubMed Open Access PDF

Haensch VG, Neuwirth T, Steinmetzer J, Kloss F, Beckert R, Gräfe S, Kupfer S, Hertweck C (2019) Metal-free aryl cross-coupling directed by traceless linkers. Chem Eur J 25(70), 16068-16073. Details PubMed Open Access PDF

Herisse M, Ishida K, Porter JL, Howden B, Hertweck C, Stinear TP, Pidot SJ (2019) Identification and mobilization of a cryptic antibiotic biosynthesis gene locus from a human-pathogenic nocardia isolate. ACS Chem Biol 15(5), 1161-1168. Details PubMed

Hermenau R, Mehl JL, Ishida K, Dose B, Pidot SJ, Stinear TP, Hertweck C (2019) Genomics-driven discovery of NO-donating diazeniumdiolate siderophores in diverse plant-associated bacteria. Angew Chem Int Ed 58(37), 13024-13029. Details PubMed Open Access PDF

König S, Pace S, Pein H, Heinekamp T, Kramer J, Romp E, Straßburger M, Troisi F, Proschak A, Dworschak J, Scherlach K, Rossi A, Sautebin L, Haeggström JZ, Hertweck C, Brakhage AA, Gerstmeier J, Proschak E, Werz O (2019) Gliotoxin from Aspergillus fumigatus abrogates leukotriene B4 formation through inhibition of leukotriene A4 hydrolase. Cell Chem Biol 26(4), 524-534. Details PubMed Open Access PDF