Uwe Knüpfer

Uwe Knüpfer

Bio Pilot Plant +49 3641 532-1130 uwe.knuepfer@leibniz-hki.de

Publications

Ishida K, Shabuer G, Schieferdecker S, Pidot SJ, Stinear TP, Knuepfer U, Cyrulies M, Hertweck C (2020) Oak-associated negativicute equipped with ancestral aromatic polyketide synthase produces antimycobacterial dendrubins. Chem Eur J 26(58), 13147-13151.
Schieferdecker S, Shabuer G, Knuepfer U, Hertweck C (2019) Clostrindolin is an antimycobacterial pyrone alkaloid from Clostridium beijerinckii. Org Biomol Chem 17(25), 6119-6121.
Garvey M, Baumann M, Wulff M, Kumar ST, Markx D, Morgado I, Knüpfer U, Horn U, Mawrin C, Fändrich M, Balbach J (2016) Molecular architecture of Aβ fibrils grown in cerebrospinal fluid solution and in a cell culture model of Aβ plaque formation. Amyloid 23(2), 76-85.
Luo T, Krüger T, Knüpfer U, Kasper L, Wielsch N, Hube B, Kortgen A, Bauer M, Giamarellos-Bourboulis EJ, Dimopoulos G, Brakhage AA, Kniemeyer O (2016) Immunoproteomic analysis of antibody responses to extracellular proteins of Candida albicans revealed the importance of glycosylation for antigen recognition. J Proteome Res 15(8), 2394-2406.
Wulff M, Baumann M, Thümmler A, Yadav JK, Heinrich L, Knüpfer U, Schlenzig D, Schierhorn A, Rahfeld JU, Horn U, Balbach J, Demuth HU, Fändrich M (2016) Enhanced Fibril Fragmentation of N-Terminally Truncated and Pyroglutamyl-Modified Aβ Peptides. Angew Chem Int Ed 55(16), 5081-5084.
Biermann M, Bardl B, Vollstädt S, Linnemann J, Knüpfer U, Seidel G, Horn U (2013) Simultaneous analysis of the non-canonical amino acids norleucine and norvaline in biopharmaceutical-related fermentation processes by a new ultra-high performance liquid chromatography approach. Amino Acids 44(4), 1225-1231.
Biermann M, Linnemann J, Knüpfer U, Vollstädt S, Bardl B, Seidel G, Horn U (2013) Trace element associated reduction of norleucine and norvaline accumulation during oxygen limitation in a recombinant Escherichia coli fermentation. Microb Cell Fact 12, 116.
Garvey M, Tepper K, Haupt C, Knüpfer U, Klement K, Meinhardt J, Horn U, Balbach J, Fändrich M (2011) Phosphate and HEPES buffers potently affect the fibrillation and oligomerization mechanism of Alzheimer's Aβ peptide. Biochem Biophys Res Commun 409(3), 385-388.
Borowski A, Kuepper M, Horn U, Knüpfer U, Zissel G, Höhne K, Luttmann W, Krause S, Virchow JC, Friedrich K (2008) Interleukin-13 acts as an apoptotic effector on lung epithelial cells and induces pro-fibrotic gene expression in lung fibroblasts. Clin Exp Allergy 38(4), 619-628.
Richter ME, Traitcheva N, Knüpfer U, Hertweck C (2008) Sequential asymmetric polyketide heterocyclization catalyzed by a single cytochrome P450 monooxygenase (AurH). Angew Chem Int Ed Engl 47(46), 8872-8875.