(2015)
Activity of α-aminoadipate reductase depends on the N-terminally extending domain.
Chembiochem 16,
1426-1430.
Dirk Hoffmeister
Pharmaceutical Microbiology · Head +49 3641 9-49850 dirk.hoffmeister@leibniz-hki.deCurriculum vitae
Main Research Areas
- Biochemical and genetic basis of fungal natural product biosyntheses
- Natural products of basidiomycetes and Ralstonia solanacearum
- Microbial nonribosomal peptide synthetases
Professional Career
2014- | Full Professor for Pharmaceutical Microbiology, FSU Jena and HKI Jena |
2009-2014 | Associate Professor for Pharmaceutical Biology, FSU Jena and head of the associated department Pharmaceutical Biology at the HKI Jena |
2007-2009 | Assistant Professor (tenure track) University of Minnesota, Saint Paul, MN, USA |
2008 | Habilitation in Pharmaceutical Biology and Biotechnology, Albert-Ludwigs-University Freiburg |
2004-2007 | Junior Group Leader, Institute for Pharmacy, Albert-Ludwigs-University, Freiburg |
2002-2004 | Postdoc, University of Wisconsin, Madison, WI, USA (DFG-fellowship) |
2002 | Dr. rer. nat., Faculty of Chemistry and Pharmacy, Albert-Ludwigs-University, Freiburg |
1998 | Diploma in biology at the Eberhard-Karls-University, Tübingen |
Awards · Appointments · Scientific Activities
Since 2020 | Head of the Institute for Pharmacy, FSU Jena |
2016-2019 | Dean for Study Affairs in the Faculty of Biology and Pharmacy, FSU Jena |
2013-2016 | Scientific advisory board, Vereinigung für Allgemeine und Angewandte Mikrobiologie (VAAM). |
Publications
(2015)
Insights on the Evolution of Mycoparasitism from the Genome of Clonostachys rosea.
Genome Biol Evol 7,
465-480.
(2015)
Fungal natural products-the mushroom perspective.
Front Microbiol 6,
127.
(2014)
Cytotoxic and antifungal activities of melleolide antibiotics follow dissimilar structure-activity relationships.
Phytochemistry 105,
101-108.
(2014)
Melleolides induce rapid cell death in human primary monocytes and cancer cells.
Bioorg Med Chem 22,
3856-3861.
(2014)
Biosynthesis of the Halogenated Mycotoxin Aspirochlorine in Koji Mold Involves a Cryptic Amino Acid Conversion.
Angew Chem Int Ed Engl 53,
13409-13413.
(2014)
Analysis of the Phlebiopsis gigantea Genome, Transcriptome and Secretome Provides Insight into Its Pioneer Colonization Strategies of Wood.
PLOS Genet 10,
e1004759.
(2014)
Functional and phylogenetic divergence of fungal adenylate-forming reductases.
Appl Environ Microbiol 80,
6175-6183.
(2014)
Comments on the distribution and phylogeny of type I polyketide synthases and nonribosomal peptide synthetases in eukaryotes.
Proc Natl Acad Sci U S A 111,
E3946.
(2014)
Injury-induced biosynthesis of methyl-branched polyene pigments in a white-rotting basidiomycete
J Nat Prod 77,
2658-2663.