Prof. Dr. Gianni Panagiotou

Microbiome Dynamics · Head +49 3641 532-1759 gianni.panagiotou@leibniz-hki.de

Curriculum vitae

Main Research Areas

Microbiome in health and disease
Systems biology of infections diseases
Personalized nutrition

Publications

Soll D^*, Chu CF^*, Sun S^*, Lutz V, Arunkumar M, Gachechiladze M, Schäuble S, Alissa-Alkhalaf M, Nguyen T, Khalil MA, Garcia-Ribelles I, Mueller M, Buder K, Michalke B, Panagiotou G, Ziegler-Martin K, Benz P, Schatzlmaier P, Hiller K, Stockinger H, Luu M, Schober K, Moosmann C, Schamel WW, Huber M, Zielinski CE^# (2024) Sodium chloride in the tumor microenvironment enhances T cell metabolic fitness and cytotoxicity. Nat Immunol 25(10), 1830-1844.

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Sprague JL, Schille TB, Allert S, Trümper V, Lier A, Großmann P, Priest EL, Tsavou A, Panagiotou G, Naglik JR, Wilson D, Schäuble S, Kasper L^*, Hube B^*^# (2024) Candida albicans translocation through the intestinal epithelial barrier is promoted by fungal zinc acquisition and limited by NFκBmediated barrier protection. PLOS Pathog 20(3), e1012031.

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Wang Y^*, Chen J^*, Ni Y, Liu Y, Gao X, Tse MA, Panagiotou G^#, Xu A^# (2024) Exercise-changed gut mycobiome as a potential contributor to metabolic benefits in diabetes prevention: an integrative multi-omics study Gut Microbes 16(1), 2416928.

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Yuu EY, Bührer C, Eckmanns T, Fulde M, Herz M, Kurzai O, Lindstedt C, Panagiotou G, Piro VC, Radonic A, Renard BY, Reuss A, Leal Siliceo S, Thielemann N, Thürmer A, van Vorst K, Wieler LH, Haller S^# (2024) The gut microbiome, resistome, and mycobiome in preterm newborn infants and mouse pups: lack of lasting effects by antimicrobial therapy or probiotic prophylaxis. Gut Pathog 16(1), 27.

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Zhou Z^*, Kleis L^*, Depetris-Chauvin A^*, Jaskulski S, Damerell V, Michels KB, Gigic B, Nöthlings U^#, Panagiotou G^# (2024) Beneficial microbiome and diet interplay in early-onset colorectal cancer. EMBO Mol Med 17(1), 9-30.

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Brandt P^*, Mirhakkak MH^*, Wagner L, Driesch D, Möslinger A, Fänder P, Schäuble S, Panagiotou G, Vylkova S^# (2023) High-throughput profiling of Candida auris isolates reveals clade-specific metabolic differences. Microbiol Spectr 11(3), e0049823. (Review)

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Chao YY, Puhach A, Frieser D, Arunkumar M, Lehner L, Seeholzer T, Garcia-Lopez A, van der Wal M, Fibi-Smetana S, Dietschmann A, Sommermann T, Ćiković T, Taher L, Gresnigt MS, Vastert SJ, van Wijk F, Panagiotou G, Krappmann D, Groß O, Zielinski CE (2023) Human TH17 cells engage gasdermin E pores to release IL-1α on NLRP3 inflammasome activation. Nat Immunol 24(2), 295-308.

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Chen J^*, Leal Siliceo S^*, Ni Y, Nielsen HB, Xu A, Panagiotou G (2023) Identification of robust and generalizable biomarkers for microbiome-based stratification in lifestyle interventions. Microbiome 11(1), 178.

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Csader S^*, Chen X^*, Leung H^*, Männistö V, Pentikäinen H, Tauriainen MM, Savonen K, El-Nezami H, Schwab U^#, Panagiotou G^# (2023) Gut ecological networks reveal associations between bacteria, exercise and clinical profile in non-alcoholic fatty liver disease patients. mSystems 8(5), e0022423.

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Häder A^#, Schäuble S^#, Gehlen J, Thielemann N, Buerfent BC, Schüller V, Hess T, Wolf T, Schröder J, Weber M, Hünniger K, Löffler J, Vylkova S, Panagiotou G, Schumacher J, Kurzai O (2023) Pathogen-specific innate immune response patterns are distinctly affected by genetic diversity. Nat Commun 14(1), 3239.

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