Curriculum vitae

Main Research Areas
  • Development and characterization of online measurement techniques
  • Viscous biological systems
  • Mixed culture processes
Professional Career
Since 12/2017 Deputy Department Head of Bio Pilot Plant, HKI
2015 - 2017 Group Leader, AVT Biochemical Engineering, RWTH Aachen University
2014 – 2015 Research Professor at Western University, London, Ontario, Kanada
2012 - 2014 Group Leader , AVT Biochemical Engineering, RWTH Aachen University
2007 – 2011 PhD Studies, RWTH Aachen University
2000 – 2007 Diploma Studies in Process Technology, TU Dresden
Awards · Appointments · Scientific Activities
2014 - 2015 Theodore von Kármán Fellowship (RWTH Aachen University)
2014 - 2015 Western Fellowship (Western University, London, Ontario)
Since 2017 Membership Zukunftsforum Biotechnologie (DECHEMA)
Since 2014 Membership BioFuelNet Canada
Since 2007 Membership Bioverfahrenstechnik Dresden e. V.


Kreyenschulte D, Heyman B, Eggert A, Maßmann T, Kalvelage C, Kossack R, Regestein L, Jupke A, Büchs J. (2018) In situ reactive extraction of itaconic acid during fermentation of Aspergillus terreus. Biochem Eng J 135, 133-141.
Regestein L, Klement T, Grande P, Kreyenschulte D, Heyman B, Maßmann T, Eggert A, Sengpiel R, Wang Y, Wierckx N, Blank LM, Spiess A, Leitner W, Bolm C, Wessling M, Jupke A, Rosenbaum M, Büchs J (2018) From beech wood to itaconic acid: Case study on biorefinery process integration. Biotechnol Biofuels 11, 279. (Review)
Antonov E, Schlembach I, Regestein L, Rosenbaum MA, Büchs J (2017) Process relevant screening of cellulolytic organisms for consolidated bioprocessing. Biotechnol Biofuels 10, 106.
Lara AR, Jaén KE, Sigala JC, Mühlmann M, Regestein L, Büchs J (2017) Characterization of Endogenous and Reduced Promoters for Oxygen-Limited Processes Using Escherichia coli. ACS Synth Biol 6(2), 344-356.
Lara AR, Jaén KE, Sigala JC, Regestein L, Büchs J (2017) Evaluation of microbial globin promoters for oxygen-limited processes using Escherichia coli. J Biol Eng 11, 39.
Schelden M, Lima W, Doerr E, Wunderlich M, Rehmann L, Büchs J, Regestein L (2017) Online measurement of viscosity for xanthan production in stirred tank reactors. Biotechnology and Bioengineering 114(5), 990-997.
Schlembach I, Regestein L, Rosenbaum MA (2017) Etablierung filamentöser Mischkulturen für Bioprozesse. BIOSpectrum 23(3), 270-272.
Antonov E, Wirth S, Gerlach T, Schlembach I, Rosenbaum MA, Regestein L, Büchs J (2016) Efficient evaluation of cellulose digestibility by Trichoderma reesei Rut-C30 cultures in online monitored shake flasks. Microb Cell Fact 15(1), 164.
Kreyenschulte D, Emde F, Regestein L, Büchs J (2016) Computational minimization of the specific energy demand of large-scale aerobic fermentation processes based on small-scale data. Chemical Engineering Science 153, 270-283.
Meier K, Carstensen F, Wessling M, Regestein L, Büchs L (2016) Quasi-continuous fermentation in a reverse-flow diafiltration bioreactor. Biochemical Engineering Journal 91, 265-275.