Johann Kufs

Johann Kufs

Bio Pilot Plant +49 3641 532-1732 Johann.Kufs@leibniz-hki.de

Publications

Bissell AU, Rautschek J, Hoefgen S, Raguž L, Mattern DJ, Saeed N, Janevska S, Jojić K, Huang Y, Kufs JE, Herboeck B, Guo H, Hillmann F, Beemelmanns C, Valiante V (2022) Biosynthesis of the sphingolipid inhibitors sphingofungins in filamentous fungi requires aminomalonate as a metabolic precursor. ACS Chem Biol 17(2), 386-394.
Kufs JE, Reimer C, Stallforth P, Hillmann F, Regestein L (2022) The potential of amoeba-based processes for natural product syntheses. Curr Opin Biotechnol 77, 102766. (Review)
Reimer C, Kufs JE, Rautschek J, Regestein L, Valiante V, Hillmann F (2022) Engineering the amoeba Dictyostelium discoideum for biosynthesis of a cannabinoid precursor and other polyketides. Nat Biotechnol 40(5), 751-758.
Kufs JE, Hoefgen S, Rautschek J, Bissell AU, Graf C, Fiedler J, Braga D, Regestein L, Rosenbaum MA, Thiele J, Valiante V (2020) Rational design of flavonoid production routes using combinatorial and precursor-directed biosynthesis. ACS Synth Biol 9(7), 1823-1832.
Hoefgen S, Lin J, Fricke J, Stroe MC, Mattern DJ, Kufs JE, Hortschansky P, Brakhage AA, Hoffmeister D, Valiante V (2018) Facile assembly and fluorescence-based screening method for heterologous expression of biosynthetic pathways in fungi. Metab Eng 48, 44-51.
Laitem C, Zaborowska J, Isa NF, Kufs J, Dienstbier M, Murphy S (2015) CDK9 inhibitors define elongation checkpoints at both ends of RNA polymerase II-transcribed genes. Nat Struct Mol Biol 22(5), 396-403.