Miriam Agler-Rosenbaum

Prof. Dr. Miriam Agler-Rosenbaum

Bio Pilot Plant · Head of Department

Phone: +49 3641 532-1120 Fax: +49 3641 532-2120 Email: miriam.rosenbaum@leibniz-hki.de

Main Research Areas
  • Bioelectrochemical systems
  • Defined microbial mixed cultures
Curriculum vitae

Professional Career

Seit 2017 Chair of Synthetic Biotechnology at Friedrich Schiller University Jena and Head of Bio Pilot Plant, Leibniz Institute for Natural Product Research and Infection Biology, (HKI) Jena
2011-2017 Junior professor in the field of Microbiology of Defined Mixed Cultures, Institute of Applied Microbiology, RWTH Aachen University, Germany
2009-2011 Research Associate/Sub-Group Leader Department of Biological and Environmental Engineering, Cornell University, Ithaca, NY, USA 
2007-2008 Post-Doc, Washington University in St. Louis, USA
2004-2006 PhD Studies, University of Greifswald, Germany
1999-2004 Diploma Studies in Biochemistry University of Greifswald

Awards · Appointments · Scientific Activities

2004-2006 Fellowship of the Fond der Chemischen Industrie

Schlembach I, Grünberger A, Rosenbaum M, Regestein L (2021) Measurement techniques to resolve and control population dynamics of mixed-culture processes. Trends in Biotech 2044, 1-17. Details PubMed Open Access PDF

Agostino V, Lenic A, Bardl B, Rizzotto V, Phan A, Blank L, Rosenbaum M (2020) Electrophysiology of the facultative autotrophic bacterium Desulfosporosinus orientis. Front Bioeng Biotechnol 8, 457. Details PubMed Open Access PDF

Askitosari T, Berger C, Tiso T, Harnisch F, Blank L, Rosenbaum M (2020) Coupling an electroactive Pseudomonas putida 2 KT2440 with bioelectrochemical rhamnolipid production. Microorganisms 8(12), 1959. Details PubMed Open Access

Fricke J, Kargbo R, Regestein L, Lenz C, Peschel G, Rosenbaum MA, Sherwood A, Hoffmeister D (2020) Scalable hybrid synthetic/biocatalytic route to psilocybin. Chem Eur J 37(26), 8281-8285. Details PubMed Open Access PDF

Hengoju S, Wohlfeil S, Munser AS, Shvydkiv O, Boehme S, Beckert E, Tovar M, Roth M, Rosenbaum M (2020) Optofluidic detection setup for multi-parametric analysis of microbiological samples in droplets. Biomicrofluidics 14(2), 024109. Details PubMed Open Access PDF

Klapper M, Schlabach K, Paschold A, Zhang S, Chowdhury S, Menzel KD, Rosenbaum MA, Stallforth P (2020) Biosynthesis of pseudomonas-derived butenolides. Angew Chem Int Ed 59(14), 5607-5610. Details PubMed Open Access PDF

Kufs JE, Hoefgen S, Rautschek J, Bissell AU, Graf C, Fiedler J, Braga D, Regestein L, Rosenbaum MA, Thiele J, Valiante V (2020) Rational design of flavonoid production routes using combinatorial and precursor-directed biosynthesis. ACS Synth Biol 9(7), 1823-1832. Details PubMed Open Access PDF

Pasternak G, Askitosari TD, Rosenbaum MA (2020) Biosurfactants and synthetic surfactants in bioelectrochemical systems: A mini-review. Front Microbiol 11, 358. Details PubMed Open Access PDF

Schlembach I, Tehrani H, Blank LM, Büchs J, Wierckx N, Regestein L, Rosenbaum M (2020) Consolidated bioprocessing of cellulose to itaconic acid by a co-culture of Trichoderma Reesei and Ustilago Maydis. Biotechnol Biofuels 13(1), 207. Details PubMed Open Access PDF

Schmitz S, Rosenbaum M (2020) Controlling the Production of Pseudomonas Phenazines by Modulating the Genetic Repertoire. ACS Chem Biol 15(12), 3244-3252. Details PubMed

Tovar M, Mahler L, Buchheim S, Roth M, Rosenbaum M (2020) Monitoring and external control of pH in microfluidic droplets during microbial culturing. Microb Cell Fact 19(1), 16. Details PubMed Open Access PDF

Askitosari TD, Boto S, Blank LM, Rosenbaum M (2019) Boosting heterologous phenazine production in Pseudomonas putida KT2440 through the exploration of the natural sequence space. Front Microbiol 10, 1990. Details PubMed Open Access

Farber P, Gräbel J, Kroppen N, Pötschke L, Roos D, Rosenbaum M, Stegschuster G, Ueberholz P. (2019) Electricity generation in a microbial fuel cell with textile carbon fibre anodes. Comput Math Appl , Details

Kirchner K, Brückner I, Klaer K, Hammers-Wirtz M, Pinnekamp J, Rosenbaum M.A. (2019) Microbial counts and antibiotic resistances during conventional wastewater treatment and wastewater ozonation. Ozone: Science & Engineering 42(2), 108-119. Details PDF

Pötschke L, Huber P, Schriever S, Rizzotto V, Gries T, Blank LM, Rosenbaum M (2019) Rational selection of carbon fiber properties for high-performance textile electrodes in bioelectrochemical systems. Front Energy Res 7, 100. Details Open Access

Agostino V, Rosenbaum M (2018) Sulfate-reducing electroautotrophs and their applications in bioelectrochemical systems. Front Energy Res 6, 55. (Review) Details Open Access

Brückner I, Kirchner K, Müller Y, Schiwy S, Klaer K, Dolny R, Wendt L, Könemann S, Pinnekamp J, Hollert H, Rosenbaum MA (2018) Status quo report on wastewater treatment plant, receiving water's biocoenosis and quality as basis for evaluation of large-scale ozonation process. Water Sci Technol 77(2), 337-345. Details PubMed Open Access

Brückner I, Stepkes H, Reichert J, Kirschner K, Rosenbaum M, Glasen S, Hammers-Witrz M, Schiwy S, Müller Y, Shuliakevich A, Hollert H, Kohlgruber V, Klaer K, Pinnekamp J. (2018) Abwasserozonung - Evaluierung des Nutzens für die aquatische Umwelt. wwt , 41-44. Details Open Access

Regestein L, Klement T, Grande P, Kreyenschulte D, Heyman B, Maßmann T, Eggert A, Sengpiel R, Wang Y, Wierckx N, Blank LM, Spiess A, Leitner W, Bolm C, Wessling M, Jupke A, Rosenbaum M, Büchs J (2018) From beech wood to itaconic acid: Case study on biorefinery process integration. Biotechnol Biofuels 11, 279. Details PubMed Open Access PDF

Schmitz S, Rosenbaum M (2018) Boosting mediated electron transfer in bioelectrochemical systems with tailored defined microbial cocultures. Biotech Bioeng 115(9), 2183-2193. Details PubMed

Antonov E, Schlembach I, Regestein L, Rosenbaum MA, Büchs J (2017) Process relevant screening of cellulolytic organisms for consolidated bioprocessing. Biotechnol Biofuels 10, 106. Details PubMed

Berger C, Rosenbaum MA (2017) Spontaneous quorum sensing mutation modulates electroactivity of Pseudomonas aeruginosa PA14. Bioelectrochemistry 117, 1-8. Details PubMed

Bosire EM, Rosenbaum MA (2017) Electrochemical Potential Influences Phenazine Production, Electron Transfer and Consequently Electric Current Generation by Pseudomonas aeruginosa. Front Microbiol [Accepted] Details PubMed

Rosenbaum MA, Berger C, Schmitz S, Uhlig R (2017) Microbial Electrosynthesis I: Pure and Defined Mixed Culture Engineering. Adv Biochem Eng Biotechnol 167, 181-202. Details PubMed

Schlembach I, Regestein L, Rosenbaum MA (2017) Etablierung filamentöser Mischkulturen für Bioprozesse. BIOSpectrum 23(3), 270-272. Details Open Access

Bosire EM, Blank LM, Rosenbaum MA (2016) Strain- and Substrate-Dependent Redox Mediator and Electricity Production by Pseudomonas aeruginosa. Appl Environ Microbiol 82(16), 5026-5038. Details PubMed

Molitor B, Kirchner K, Henrich AW, Schmitz S, Rosenbaum MA (2016) Expanding the molecular toolkit for the homoacetogen Clostridium ljungdahlii. Sci Rep 6, 31518. Details PubMed Open Access

Schröder U, Greiner A, Rosenbaum MA, Harnisch F (2016) Mikrobielle Elektrochemie: Wie Mikroorganismen und Elektroden interagieren Nachrichten aus der Chemie 64(7-8), 732-737. Details

Schmitz S, Nies S, Wierckx N, Blank LM, Rosenbaum MA (2015) Engineering mediator-based electroactivity in the obligate aerobic bacterium Pseudomonas putida KT2440. Front Microbiol 6, 284. Details PubMed

Rosenbaum MA, Franks AE (2014) Microbial catalysis in bioelectrochemical technologies: status quo, challenges and perspectives. Appl Microbiol Biotechnol 98(2), 509-518. Details PubMed

Rosenbaum MA, Henrich AW (2014) Engineering microbial electrocatalysis for chemical and fuel production. Curr Opin Biotechnol 29, 93-98. Details PubMed

TerAvest MA, Rosenbaum MA, Kotloski NJ, Gralnick JA, Angenent LT (2014) Oxygen allows Shewanella oneidensis MR-1 to overcome mediator washout in a continuously fed bioelectrochemical system Biotechnology 111(4), 692-699. Details PDF

Venkataraman A, Rosenbaum MA, Werner JJ, Winans SC, Angenent LT (2014) Metabolite transfer with the fermentation product 2,3-butanediol enhances virulence by Pseudomonas aeruginosa. ISME J 8(6), 1210-1220. Details PubMed PDF

Angenent LT, Rosenbaum M (2013) Microbial electrocatalysis to guide biofuel and biochemical bioprocessing Biofuels 4(2), 131-134. Details

Friedman ES, Rosenbaum MA, Lee AW, Lipson DA, Land BR, Angenent LT (2012) A cost-effective and field-ready potentiostat that poises subsurface electrodes to monitor bacterial respiration. Biosens Bioelectron 32(1), 309-313. Details PubMed

Li Z, Venkataraman A, Rosenbaum MA, Angenent LT (2012) A laminar-flow microfluidic device for quantitative analysis of microbial electrochemical activity. ChemSusChem 5(6), 1119-1123. Details PubMed

Rosenbaum MA, Bar HY, Beg QK, Segrè D, Booth J, Cotta MA, Angenent LT (2012) Transcriptional analysis of Shewanella oneidensis MR-1 with an electrode compared to Fe(III)citrate or oxygen as terminal electron acceptor. PLOS One 7(2), e30827. Details PubMed

Rosenbaum MA, Bar HY, Beg QK, Segrè D, Booth J, Cotta MA, Angenent LT (2011) Shewanella oneidensis in a lactate-fed pure-culture and a glucose-fed co-culture with Lactococcus lactis with an electrode as electron acceptor. Bioresour Technol 102(3), 2623-2628. Details PubMed

Venkataraman A, Rosenbaum MA, Perkins SD, Werner JJ, Angenent LT (2011) Metabolite-based mutualism between Pseudomonas aeruginosaPA14 and Enterobacter aerogenes enhances current generation in bioelectrochemical systems Energy Environ. Sci. 4, 4550-4559. Details