Publications

Huang Y, Höfgen S, Valiante V (2021) Biosynthesis of fungal drimane-type sesquiterpene esters. Angew Chem Int Ed 60(44), 23763-23770.
Furukawa T, Scheven MT, Misslinger M, Zhao C, Hoefgen S, Gsaller F, Lau J, Jöchl C, Donaldson I, Valiante V, Brakhage AA, Bromley MJ, Haas H, Hortschansky P (2020) The fungal CCAAT-binding complex and HapX display highly variable but evolutionary conserved synergetic promoter-specific DNA recognition. Nucleic Acids Res 48(7), 3567-3590.
Janevska S, Ferling I, Jojić K, Rautschek J, Hoefgen S, Proctor RH, Hillmann F, Valiante V (2020) Self-protection against the sphingolipid biosynthesis inhibitor fumonisin B1 is conferred by a FUM cluster-encoded ceramide synthase. mBio 11(3), e00455-20.
Köhler T, Heida T, Hoefgen S, Weigel N, Valiante V, Thiele J (2020) Cell-free protein synthesis and in situ immobilization of deGFP-MatB in polymer microgels for malonate-to-malonyl CoA conversion. RSC Adv 10, 40588-40596.
Krishnan BP, Prieto-Lopez LO, Hoefgen S, Xue L, Wang S, Valiante V, Cui J (2020) A thermo-magneto-responsive smart biocatalyst for malonyl Coenzyme A synthesis. ACS Appl Mater Interfaces 12(18), 20982-20990.
Kufs JE, Hoefgen S, Rautschek J, Bissell AU, Graf C, Fiedler J, Braga D, Regestein L, Rosenbaum MA, Thiele J, Valiante V (2020) Rational design of flavonoid production routes using combinatorial and precursor-directed biosynthesis. ACS Synth Biol 9(7), 1823-1832.
Manfiolli AO, Siqueira FS, Dos Reis TF, Van Dijck P, Schrevens S, Hoefgen S, Föge M, Straßburger M, de Assis LJ, Heinekamp T, Rocha MC, Janevska S, Brakhage AA, Malavazi I, Goldman GH, Valiante V (2019) Mitogen-activated protein kinase cross-talk interaction modulates the production of melanins in Aspergillus fumigatus. mBio 10(2), e00215-19.
Hoefgen S, Lin J, Fricke J, Stroe MC, Mattern DJ, Kufs JE, Hortschansky P, Brakhage AA, Hoffmeister D, Valiante V (2018) Facile assembly and fluorescence-based screening method for heterologous expression of biosynthetic pathways in fungi. Metab Eng 48, 44-51.
Hoefgen S, Dahms SO, Oertwig K, Than ME (2015) The amyloid precursor protein shows a pH-dependent conformational switch in its E1 domain. J Mol Biol 427(2), 433-442.
Coburger I, Hoefgen S, Than ME (2014) The structural biology of the amyloid precursor protein APP - a complex puzzle reveals its multi-domain architecture. Biol Chem 395(5), 485-498.