Dr. Sandra Höfgen

Alumni

Publications

Hoefgen S, Lin J, Fricke J, Stroe MC, Mattern DJ, Kufs JE, Hortschansky P, Brakhage AA, Hoffmeister D, Valiante V (2018) Facile assembly and fluorescence-based screening method for heterologous expression of biosynthetic pathways in fungi. Metab Eng 48, 44-51.
Hoefgen S, Dahms SO, Oertwig K, Than ME (2015) The amyloid precursor protein shows a pH-dependent conformational switch in its E1 domain. J Mol Biol 427(2), 433-442.
Coburger I, Hoefgen S, Than ME (2014) The structural biology of the amyloid precursor protein APP - a complex puzzle reveals its multi-domain architecture. Biol Chem 395(5), 485-498.
Hoefgen S, Coburger I, Roeser D, Schaub Y, Dahms SO, Than ME (2014) Heparin induced dimerization of APP is primarily mediated by E1 and regulated by its acidic domain. J Struct Biol 187(1), 30-37.
Honarmand Ebrahimi K, Dienemann C, Hoefgen S, Than ME, Hagedoorn PL, Hagen WR (2013) The amyloid precursor protein (APP) does not have a ferroxidase site in its E2 domain. PLOS One 8(8), e72177.
Dahms SO, Hoefgen S, Roeser D, Schlott B, Gührs KH, Than ME (2010) Structure and biochemical analysis of the heparin-induced E1 dimer of the amyloid precursor protein. Proc Natl Acad Sci U S A 107(12), 5381-5386.