(2022)
Biosynthesis of the sphingolipid inhibitors sphingofungins in filamentous fungi requires aminomalonate as a metabolic precursor.
ACS Chem Biol 17(2),
386-394.
Dr. Slavica Janevska
(Epi-)Genetic Regulation of Fungal Virulence · Head +49 3641 532-1188 slavica.janevska@leibniz-hki.deCurriculum vitae
Professional Career
| 2023 | Junior research group leader, Leibniz Institute for Natural Product Research and Infection Biology - Hans Knöll Institute - (Leibniz-HKI), Jena |
| 2022 | Postdoc, junior research group Biobricks of Microbial Natural Product Syntheses (Dr. Vito Valiante), Leibniz-HKI, Jena |
| 2019-2022 | Visiting researcher (fellowships from the German Research Foundation and the Foundation van Wijck-Stam-Caspersfonds), Dept. Molecular Plant Pathology (Prof. Martijn Rep), University of Amsterdam, Netherlands |
| 'The role of histone modifications in Fusarium oxysporum pathogenicity' | |
| 2018-2019 | Postdoc, junior research group Biobricks of Microbial Natural Product Syntheses (Dr. Vito Valiante), Leibniz-HKI, Jena |
| 2017 | Postdoc, Dept. Molecular Biotechnology of Fungi (Prof. Bettina Tudzynski), Westfälische Wilhelms-Universität Münster (WWU Münster) |
| 2014-2017 | PhD with honors (summa cum laude), Dept. Molecular Biotechnology of Fungi (Prof. Bettina Tudzynski), WWU Münster |
| Dissertation ‘Exploring the biosynthesis and regulation of novel secondary metabolite gene clusters in Fusarium fujikuroi via a combination of bioinformatic, molecular and chemical approaches’ | |
| 2011-2014 | Master of Science in Biotechnology, WWU Münster |
| 2012 | International research stay, University of Bristol, UK |
| 2008-2011 | Bachelor of Science in Biosciences, WWU Münster |
| 2008 | Abitur (A-levels), Heinrich-Heine-Gymnasium Oberhausen |
Topics
Publications
(2020)
Self-protection against the sphingolipid biosynthesis inhibitor fumonisin B1 is conferred by a FUM cluster-encoded ceramide synthase.
mBio 11(3),
e00455-20.
(2019)
Mitogen-activated protein kinase cross-talk interaction modulates the production of melanins in Aspergillus fumigatus.
mBio 10(2),
e00215-19.
(2018)
Elucidation of the two H3K36me3 histone methyltransferases Set2 and Ash1 in Fusarium fujikuroi unravels their different chromosomal targets and a major impact of Ash1 on genome stability.
Genetics 208(1),
153-171.
(2018)
Set1 and Kdm5 are antagonists for H3K4 methylation and regulators of the major conidiation-specific transcription factor gene ABA1 in Fusarium fujikuroi.
Environ Microbiol
[Epub ahead of print]
(2018)
Secondary metabolism in Fusarium fujikuroi: strategies to unravel the function of biosynthetic pathways.
Appl Microbiol Biotechnol 102(2),
615-630.
(2018)
Analysis of the global regulator Lae1 uncovers a connection between Lae1 and the histone acetyltransferase HAT1 in Fusarium fujikuroi.
Appl Microbiol Biotechnol 102(1),
279-295.
(2017)
A Fungal N-Dimethylallyltryptophan Metabolite from Fusarium fujikuroi.
Chembiochem 18(10),
899-904.
(2017)
Establishment of the Inducible Tet-On System for the Activation of the Silent Trichosetin Gene Cluster in Fusarium fujikuroi.
Toxins (Basel) 9(4),
(2017)
Comparative genomics of geographically distant Fusarium fujikuroi isolates revealed two distinct pathotypes correlating with secondary metabolite profiles.
PLOS Pathog 13(10),
e1006670.
