Global transcriptional response of human liver cells to ethanol stress of different strength reveals hormetic behavior.
(2017) Global transcriptional response of human liver cells to ethanol stress of different strength reveals hormetic behavior. Alcohol Clin Exp Res 41(5), 883-894. PubMed
The liver is the major site for alcohol metabolism in the body and therefore, the primary target organ for ethanol-induced toxicity. In this study, we investigated the in vitro response of human liver cells to different ethanol concentrations in a perfused bioartificial liver device that mimics the complex architecture of the natural organ.
doi: 10.1111/acer.13361 PMID: 28226195