Grit Walther

Dr. Grit Walther

National Reference Center for Invasive Fungal Infections

Phone: +49 3641 532-1038 Fax: +49 3641 532-2038 Email: grit.walther@leibniz-hki.de

Publications

Böttcher S, Hartung S, Meyer F, Rummler S, Voigt K, Walther G, Hochhaus A, von Lilienfeld-Toal M, Jahreis S (2021) Human mucosal-associated invariant T cells respond to Mucorales species in a MR1-dependent manner. Med Mycol , 505-509. Details PubMed

Barber AE, Scheufen S, Walther G, Kurzai O, Schmidt V (2020) Low rate of azole resistance in cases of avian aspergillosis in Germany. Med Mycol 58(8), 1187-1190. Details PubMed

Brasch J, Beck-Jendroschek V, Walther G, Rubbel D (2020) Clinical isolates of Trichophyton rubrum are completely inhibited by photochemical treatment with a γ-cyclodextrin formulation of curcuminoids. Mycoses 63(4), 369-375. Details PubMed Open Access PDF

Geiser DM, Al-Hatmi A, Aoki T, Arie T, Balmas V, Barnes I, Bergstrom GC, Bhattacharyya MKK, Blomquist CL, Bowden R, Brankovics B, Brown DW, Burgess LW, Bushley K, Busman M, Cano-Lira JF, Carrillo JD, Chang HX, Chen CY, Chen W, Chilvers MI, Chulze SN, Coleman JJ, Cuomo CA, de Beer ZW, de Hoog GS, Del Castillo-Múnera J, Del Ponte E, Diéguez-Uribeondo J, Di Pietro A, Edel-Hermann V, Elmer WH, Epstein L, Eskalen A, Esposto MC, Everts KL, Fernández-Pavía SP, da Silva GF, Foroud NA, Fourie G, Frandsen RJN, Freeman S, Freitag M, Frenkel O, Fuller KK, Gagkaeva T, Gardiner DM, Glenn AE, Gold S, Gordon T, Gregory NF, Gryzenhout M, Guarro J, Gugino B, Gutiérrez S, Hammond-Kosack K, Harris LJ, Homa M, Hong CF, Hornok L, Huang JW, Ilkit M, Jacobs A, Jacobs K, Jiang C, Jimenez-Gasco MDM, Kang S, Kasson MT, Kazan K, Kennell JC, Kim H, Kistler HC, Kuldau GA, Kulik T, Kurzai O, Laraba I, Laurence MH, Lee TY, Lee YW, Lee YH, Leslie JF, Liew ECY, Lofton LW, Logrieco A, Sánchez López-Berges M, Luque AG, Lysøe E, Ma LJ, Marra RE, Martin FN, May SR, McCormick S, McGee CT, Meis JF, Migheli Q, Mohamed Nor NMI, Monod M, Moretti A, Mostert D, Mulé G, Munaut F, Munkvold GP, Nicholson P, Nucci M, O'Donnell K, Pasquali M, Pfenning LH, Prigitano A, Proctor R, Ranque S, Rehner S, Rep M, Rodríguez-Alvarado G, Rose LJ, Roth MG, Ruiz-Roldán C, Saleh AA, Salleh B, Sang H, Scandiani M, Scauflaire J, Schmale D 3rd, Short DP, Šišić A, Smith J, Smyth CW, Son H, Spahr E, Stajich JE, Steenkamp E, Steinberg C, Subramaniam R, Suga H, Summerell BA, Susca A, Swett CL, Toomajian C, Torres-Cruz TJ, Tortorano AM, Urban M, Vaillancourt LJ, Vallad GE, van der Lee T, Vanderpool D, van Diepeningen AD, Vaughan M, Venter E, Vermeulen M, Verweij PE, Viljoen A, Waalwijk C, Wallace EC, Walther G, Wang J, Ward T, Wickes B, Wiederhold NP, Wingfield MJ, Wood AKM, Xu JR, Yang XB, Yli-Matilla T, Yun SH, Zakaria L, Zhang H, Zhang N, Zhang S, Zhang X (2020) Phylogenomic analysis of a 55.1 kb 19-gene dataset resolves a monophyletic Fusarium that includes the Fusarium solani Species Complex. Phytopathology [Epub ahead of print] Details PubMed

Hagemann JB, Furitsch M, Wais V, Bunjes D, Walther G, Kurzai O, Essig A (2020) First case of fatal Rhizomucor miehei endocarditis in an immunocompromised patient. Diagn Microbiol Infect Dis 98(2), 115106. Details PubMed

Wagner L, Stielow JB, de Hoog GS, Bensch K, Schwartze VU, Voigt K, Alastruey-Izquierdo A, Kurzai O, Walther G (2020) A new species concept for the clinically relevant Mucor circinelloides complex. Persoonia 44, 67-97. Details PubMed Open Access PDF

Barber AE*, Weber M, Kaerger K, Linde J, Gölz H, Duerschmied D, Markert A, Guthke R, Walther G, Kurzai O (2019) Comparative genomics of serial Candida glabrata isolates and the rapid acquisition of echinocandin resistance during therapy. Antimicrob Agents Chemother 63(2), e01628-18. Details PubMed Open Access PDF

Hamprecht A, Barber AE, Mellinghoff SC, Thelen P, Walther G, Yu Y, Neurgaonkar P, Dandekar T, Cornely OA, Martin R, Kurzai O (2019) Candida auris in germany and previous exposure to foreign healthcare. Emerg Infect Dis 25(9), 1763-1765. Details PubMed Open Access PDF

Hassan MIA*, Cseresnyes Z*, Al-Zaben N, Dahse HM, Vilela de Oliveira RJ, Walther G, Voigt K**, Figge MT**; *shared first authors; ** authors contributed equally (2019) The geographical region of origin determines the phagocytic vulnerability of Lichtheimia strains. Environ Microbiol 21(12), 4563-4581. Details PubMed Open Access PDF Supplement

Nesseler A, Schauerte N, Geiger C, Kaerger K, Walther G, Kurzai O, Eisenberg T (2019) Sporothrix humicola (Ascomycota: Ophiostomatales) - A soil-borne fungus with pathogenic potential in the eastern quoll (Dasyurus viverrinus). Med Mycol Case Rep 25, 39-44. Details PubMed Open Access PDF

Pérez-Hansen A, Lass-Flörl C, Lackner M, Aigner M, Alastruey-Izquierdo A, Arikan-Akdagli S, Bader O, Becker K, Boekhout T, Buzina W, Cornely OA, Hamal P, Kidd SE, Kurzai O, Lagrou K, Lopes Colombo A, Mares M, Masoud H, Meis JF, Oliveri S, Rodloff AC, Orth-Höller D, Guerrero-Lozano I, Sanguinetti M, Segal E, Taj-Aldeen SJ, Tortorano AM, Trovato L, Walther G, Willinger B (2019) Antifungal susceptibility profiles of rare ascomycetous yeasts. J Antimicrob Chemother 74(9), 2649-2656. Details PubMed

Roth M, Daas L, Renner-Wilde A, Cvetkova-Fischer N, Saeger M, Herwig-Carl M, Matthaei M, Fekete A, Kakkassery V, Walther G, von Lilienfeld-Toal M, Mertens C, Lenk J, Mehlan J, Fischer C, Fuest M, Kroll S, Bayoudh W, Viestenz A, Frings A, MacKenzie CR, Messmer EM, Seitz B, Kurzai O, Geerling G (2019) Das Deutsche Pilz-Keratitis-Register: Erste Ergebnisse einer multizentrischen Erhebung [The german keratomycosis registry: Initial results of a multicenter survey]. Ophthalmologe 116(10), 957-966. Details PubMed Open Access PDF

Springer J, Walther G, Rickerts V, Hamprecht A, Willinger B, Teschner D, Einsele H, Kurzai O, Loeffler J (2019) Detection of fusarium species in clinical specimens by probe-based real-time PCR. J Fungi (Basel) 5(4), 105. Details PubMed Open Access PDF

Wagner L, de Hoog S, Alastruey-Izquierdo A, Voigt K, Kurzai O, Walther G (2019) A revised species concept for opportunistic Mucor species reveals species-specific antifungal susceptibility profiles. Antimicrob Agents Chemother 63(8), e00653-19. Details PubMed Open Access PDF

Walther G, Wagner L, Kurzai O (2019) Updates on the taxonomy of mucorales with an emphasis on clinically important taxa. J Fungi (Basel) 5(4), 106. (Review) Details PubMed Open Access

Walther G, Wagner L, Kurzai O (2019) Outbreaks of mucorales and the species involved. Mycopathologia 185(5), 765-781. (Review) Details PubMed Open Access PDF

Habbe KJ, Frings A, Schrader S, Roth M, MacKenzie C, Walther G, Kurzai O, Geerling G (2018) Tintelnotia destructans: Ein neuer Feind vor dem Tore [Tintelnotia destructans: new enemy at the gates]. Ophthalmologe 115(11), 948-950. Details PubMed PDF

Jahreis S, Böttcher S, Hartung S, Rachow T, Rummler S, Dietl AM, Haas H, Walther G, Hochhaus A, von Lilienfeld-Toal M (2018) Human MAIT cells are rapidly activated by Aspergillus spp. in an APC-dependent manner. Eur J Immunol 48(10), 1698-1706. Details PubMed Open Access

Weber M, Schaer J, Walther G, Kaerger K, Steinmann J, Rath PM, Spiess B, Buchheidt D, Hamprecht A, Kurzai O (2018) FunResDB-A web resource for genotypic susceptibility testing of Aspergillus fumigatus. Med Mycol 56(1), 117-120. Details PubMed Open Access PDF

Wijayawardene NN, Pawłowska J, Letcher PM, Kirk PM, Humber RA, Schussler A, Wrzosek M, Muszewska A, Okrasinska A, Istel L, Gesiorska A, Mungai P, Lateef AA, Rajeshkumar KC, Singh RV, Radek R, Walther G, Wagner L, Walker C, Wijesundara DSA, Papizadeh M, Dolatabadi S, Shenoy BD, Tokarev YS, Lumyong S, Hyde KD (2018) Notes for genera: basal clades of Fungi (including Aphelidiomycota, Basidiobolomycota, Blastocladiomycota, Calcarisporiellomycota, Caulochytriomycota, Chytridiomycota, Entomophthoromycota, Glomeromycota, Kickxellomycota, Monoblepharomycota, Mortierellomyc. Fungal Divers Volume 92(Issue 1), 43-129. Details

Lima DX, Souza-Motta CM, Wagner L, Voigt K, de Souza CAF, de Oliveira RJV, da Silva GA, de Azevedo Santiago ALCM, Walther G (2017) Circinella simplex - a misapplied name of Mucor circinatus sp. nov. Phytotaxa 329(3), 269. Details

Pinder N, Pelzl LH, Walther G, Backhaus J, Kurzai O, Hoppe-Tichy T (2017) Caspofungin infusion solutions (50 mg/100 mL): chemical stability and antifungal activity against Candida spp. Pharmazie 72(4), 197-199. Details PubMed

Valiante V, Mattern DJ, Schüffler A, Horn F, Walther G, Scherlach K, Petzke L, Dickhaut J, Guthke R, Hertweck C, Nett M, Thines E, Brakhage AA (2017) Discovery of an Extended Austinoid Biosynthetic Pathway in Aspergillus calidoustus. ACS Chem Biol 12(5), 1227-1234. Details PubMed Supplement

Walther G, Stasch S, Kaerger K, Hamprecht A, Roth M, Cornely OA, Geerling G, Mackenzie CR, Kurzai O, von Lilienfeld-Toal M (2017) Fusarium Keratitis in Germany. J Clin Microbiol 55(10), 2983-2995. Details PubMed

Horn F, Linde J, Mattern DJ, Walther G, Guthke R, Scherlach K, Martin K, Brakhage AA, Petzke L, Valiante V (2016) Draft genome sequences of fungus Aspergillus calidoustus. Genome Announc 4(2), e00102-16. Details PubMed

Horn F, Linde J, Mattern DJ, Walther G, Guthke R, Brakhage AA, Valiante V (2015) Draft Genome Sequence of the Fungus Penicillium brasilianum MG11. Genome Announc 3(5), e00724-15. Details PubMed

Huyke J, Martin R, Walther G, Weber M, Kaerger K, Bougnoux ME, Elias J, Kurzai O (2015) Candida albicans bloodstream isolates in a German university hospital are genetically heterogenous and susceptible to commonly used antifungals. Int J Med Microbiol 305(7), 742-747. Details PubMed

Martínez-Ramírez JA, Walther G, Peters FT (2014) Studies on drug metabolism by fungi colonizing decomposing human cadavers. Part II: biotransformation of five model drugs by fungi isolated from post-mortem material. Drug Testing and Analysis [Epub ahead of print] Details PubMed

Hoffmann K, Pawłowska J, Walther G, Wrzosek M, de Hoog GS, Benny GL, Kirk PM, Voigt K (2013) The family structure of the Mucorales: a synoptic revision based on comprehensive multigene-genealogies. Persoonia 30, 57-76. Details PubMed

Martínez-Ramírez JA, Strien J, Sanft J, Mall G, Walther G, Peters FT (2013) Studies on drug metabolism by fungi colonizing decomposing human cadavers. Part I: DNA sequence-based identification of fungi isolated from postmortem material. Anal Bioanal Chem 405(26), 8443-8450. Details PubMed

Wagner L, Stielow B, Hoffmann K, Petkovits T, Papp T, Vágvölgyi C, de Hoog GS, Verkley G, Voigt K (2013) A comprehensive molecular phylogeny of the Mortierellales (Mortierellomycotina) based on nuclear ribosomal DNA. Persoonia 30, 77-93. Details PubMed

Walther G, Pawłowska J, Alastruey-Izquierdo A, Wrzosek M, Rodriguez-Tudela JL, Dolatabadi S, Chakrabarti A, de Hoog GS (2013) DNA barcoding in Mucorales: an inventory of biodiversity. Persoonia 30, 11-47. Details PubMed

Bibashi E, de Hoog GS, Pavlidis TE, Symeonidis N, Sakantamis A, Walther G (2012) Wound infection caused by Lichtheimia ramosa due to a car accident. Med Mycol Case Rep 2, 7-10. Details PubMed

Gryganskyi AP, Humber RA, Smith ME, Miadlikowska J, Wu S, Voigt K, Walther G, Anishchenko IM, Vilgalys R (2012) Molecular phylogeny of the Entomophthoromycota. Mol Phylogenet Evol 65(2), 682-694. Details PubMed

Schoch CL, Seifert KA, Huhndorf S, Robert V, Spouge JL, Levesque CA, Chen W; Fungal Barcoding Consortium; Fungal Barcoding Consortium Author List (2012) Nuclear ribosomal internal transcribed spacer (ITS) region as a universal DNA barcode marker for fungi. Proc Natl Acad Sci U S A 109(16), 6241-6246. Details PubMed

Schrödl W, Heydel T, Schwartze VU, Hoffmann K, Grosse-Herrenthey A, Walther G, Alastruey-Izquierdo A, Rodriguez-Tudela JL, Olias P, Jacobsen ID, de Hoog GS, Voigt K (2012) Direct analysis and identification of pathogenic Lichtheimia species by matrix-assisted laser desorption ionization-time of flight analyzer-mediated mass spectrometry. J Clin Microbiol 50(2), 419-427. Details PubMed

Vitale RG, de Hoog GS, Schwarz P, Dannaoui E, Deng S, Machouart M, Voigt K, van de Sande WW, Dolatabadi S, Meis JF, Walther G (2012) Antifungal susceptibility and phylogeny of opportunistic members of the order Mucorales. J Clin Microbiol 50(1), 66-75. Details PubMed

Nagy LG, Walther G, Házi J, Vágvölgyi C, Papp T (2011) Understanding the evolutionary processes of fungal fruiting bodies: correlated evolution and divergence times in the Psathyrellaceae. Syst Biol 60(3), 303-317. Details PubMed

Alastruey-Izquierdo A, Cuesta I, Walther G, Cuenca-Estrella M, Rodriguez-Tudela JL (2010) Antifungal susceptibility profile of human-pathogenic species of Lichtheimia. Antimicrob Agents Chemother 54(7), 3058-3060. Details PubMed

Alastruey-Izquierdo A, Hoffmann K, de Hoog GS, Rodriguez-Tudela JL, Voigt K, Bibashi E, Walther G (2010) Species recognition and clinical relevance of the zygomycetous genus Lichtheimia (syn. Absidia pro parte, Mycocladus). J Clin Microbiol 48(6), 2154-2170. Details PubMed

Li L, Sattler I, Deng Z, Groth I, Walther G, Klaus-Dieter Menzel G, Peschel S, Grabley W, Lin (2008) A-seco-oleane-type triterpenes from Phomopsis sp. (strain HKI0458) isolated from the mangrove plant Hibiscus tiliaceus. Phytochemistry 69(2), 511-517. Details PubMed

Niu X, Dahse HM, Menzel KD, Lozach O, Walther G, Meijer L, Grabley S, Sattler I (2008) Butyrolactone I derivatives from Aspergillus terreus carrying an unusual sulfate moiety. J Nat Prod 71(4), 689-692. Details PubMed

Garnica S, Weiss M, Walther G, Oberwinkler F (2007) Reconstructing the evolution of agarics from nuclear gene sequences and basidiospore ultrastructure. Mycol Res 111(Pt 9), 1019-1029. Details PubMed

Walther G, Garnica S, Weiss M (2005) The systematic relevance of conidiogenesis modes in the gilled Agaricales. Mycol Res 109(Pt 5), 525-544. Details PubMed

Berg A, Görls H, Dörfelt H, Walther G, Schlegel B, Gräfe U (2000) Aureoquinone, a new protease inhibitor from Aureobasidium sp. J Antibiot (Tokyo) 53(11), 1293-1295. Details PubMed

Berg A, Reiber K, Dörfelt H, Walther G, Schlegel B, Gräfe U (2000) Laccaridiones A and B, new protease inhibitors from Laccaria amethystea. J Antibiot (Tokyo) 53(11), 1313-1316. Details PubMed