(2023) Tuning the corona-core ratio of polyplex micelles for selective oligonucleotide delivery to hepatocytes or hepatic immune cells. Biomaterials 294, 122016.
Main Research Areas
- Host-pathogen interaction on human pathogenic fungi
- Automated processing of microscopic images
- Spatiotemporal computer simulations of agent-based infection models
|since 2021||Professor (W3) for Applied Systems Biology, Friedrich Schiller University Jena|
|since 2011||Head of Research Group Applied Systems Biology, Leibniz-HKI|
|2011-2021||Professor (W2) for Applied Systems Biology, Friedrich Schiller University Jena|
|2005-2010||Junior Fellow in Theoretical Immunology at the Frankfurt Institute for Advanced Studies (FIAS) of the Goethe University Frankfurt|
|2001-2005||Research assistant in Computer Physics at the University Groningen (NL)|
|2000||Dr. rer. nat. in Physics at the University Groningen (NL)|
|1995||Diploma in Physics at the University Dortmund|
Awards · Appointments · Scientific Activities
|2011 - 2017||Adjunct Fellow at Frankfurt Institute for Advanced Studies (FIAS)|
Scientific Activities and Functions
|since 2021||Deputy Coordinator of the Jena School for Microbial Communication|
|since 2019||Coordinator of Research Area C – Data Synopsis in the Excellence Cluster “Balance of the Microverse”|
|Member of the Management Board of the Microverse Imaging Center in the Excellence Cluster “Balance of the Microverse”|
|since 2019||Speaker of Leibniz ScienceCampus “InfectoOptics”|
|since 2019||Editor: Scientific Reports|
|since 2017||Ombudsperson at the Leibniz Institute for Natural Product Research and Infection Biology|
|since 2017||PI and member of the DFG-Collaborative Research Center 1278 PolyTarget|
|since 2017||Editor: Cytometry A|
|since 2015||Member: Jena Center for Soft Matter|
|since 2015||Member: Michael Stifel Center for Data-Driven and Simulation Science|
|since 2014||PI and member of the DFG-Collaborative Research Center 124 FungiNet|
|since 2014||Editor: Computational and Mathematical Models in Medicine|
|since 2012||Organizer: Biennial international symposium on “Image-based Systems Biology” (IbSB)|
|since 2011||Organizer: Biennial international symposium on “Systems Biology of Microbial Infection” (SBMI)|
|since 2011||Member: International Leibniz Research School for Microbial and Biomolecular Interactions|
|since 2011||Member: Jena School for Microbial Communication|
(2023) The lipid raft-associated protein stomatin is required for accumulation of dectin-1 in the phagosomal membrane and for full activity of macrophages against Aspergillus fumigatus. mSphere 8(8), e0052322.
(2023) Aspergillus fumigatus hijacks human p11 to redirect fungal-containing phagosomes to non-degradative pathway. Cell Host Microbe 31(3), 373-388.
(2023) Analysis of HDACi-coupled nanoparticles: Opportunities and challenges. In: Humana, New York, NY (eds.) HDAC/HAT Function Assessment and Inhibitor Development. Methods in Molecular Biology 2589, pp. 129-144. Springer Protocols. ISBN: 978-1-0716-2787. (Review)
(2023) Guided-deconvolution for correlative light and electron microscopy. PLoS One 18(3), e0282803.
(2023) Polymer-based particles against pathogenic fungi: A non-uptake delivery of compounds. Biomater Adv 146, 213300.
(2022) Automated characterisation of neutrophil activation phenotypes in ex vivo human Candida blood infections. Comput Struct Biotechnol J 20, 2297-2308.
(2022) Acceptance of different self-sampling methods for semiweekly SARS-CoV-2 testing in asymptomatic children and childcare workers at German Day Care Centers: A nonrandomized controlled trial. JAMA Netw Open 5(9), e2231798.
(2022) Feasibility of SARS-CoV-2 surveillance testing among children and childcare workers at German Day Care Centers: A nonrandomized controlled trial. JAMA Netw Open 5(1), e2142057.