Gianni Panagiotou

Prof. Dr. Gianni Panagiotou

Microbiome Dynamics · Head +49 3641 532-1759 gianni.panagiotou@leibniz-hki.de

Curriculum vitae

Main Research Areas
  • Medical & Environmental Metagenomics: human, mice, marine, plants;
  • Systems Biology: -omics integration, chemical-protein & protein-protein interaction networks; 
  • Synthetic Biology: genome-scale metabolic modelling, design of probiotics, discovery of postbiotics

Publications

Nychas E*, Marfil-Sánchez A*, Chen X, Mirhakkak M, Li H, Jia Q, Xu A, Nielsen HB, Niewdorp M, Loomba R, Ni Y#, Panagiotou G# (2025) Discovery of robust and highly specific microbiome signatures of non-alcoholic fatty liver disease. Microbiome 13((1):10),
Xiong L, Beyer D, Liu N, Lehmann T, Neugebauer S, Schaeuble S, Sommerfeld O, Ernst P, Svensson CM, Nietzsche S, Scholl S, Bruns T, Gaßler N, Gräler MH, Figge MT, Panagiotou G, Bauer M, Press AT# (2025) Targeting protein kinase C-α prolongs survival and restores liver function in sepsis: evidence from preclinical models. Pharmacol Res [Epub ahead of print]
Bruch A*, Lazarova V*, Berg M, Krueger T, Schaeuble S, Kelani AA, Mertens B, Lehenberger P, Kniemeyer O, Kaiser S, Panagiotou G, Gsaller F, Blango MG (2024) tRNA hypomodification facilitates 5-fluorocytosine resistance via cross-pathway control system activation in Aspergillus fumigatus Nucleic Acids Res , 1-20.
Chen J, Lu RS, Diaz-Canestro C, Song E, Jia X, Liu Y, Wang C, Cheung CKY, Panagiotou G#, Xu A# (2024) Distinct changes in serum metabolites and lipid species in the onset and progression of NAFLD in obese Chinese. Comput Struct Biotechnol J 23(2024), 791-800.
Chen J*, Wang Y*, Xu A, Panagiotou G# (2024) The human gut mycobiome and its potential as a regulator of the host’s metabolic health. In: Brakhage AA, Kniemeyer O, Zipfel PF (eds.) The Mycota - Human and Animal Relationships 3. 6, pp. 121-133. Springer, Cham. ISBN: 978-3-031-64852. (Review)
Garcia Lopez A, Albrecht-Eckardt D, Panagiotou G, Schäuble S# (2024) FungiFun3: systemic gene set enrichment analysis for fungal species. Bioinformatics 40(11), btae620.
Garcia Lopez R*, Schaeuble S*, Sae-Ong T, Seelbinder B, Bauer M, Giamarellos-Bourboulis EJ, Singer M, Lukaszewski R, Panagiotou G# (2024) Risk assessment with gene expression markers in sepsis development. Cell Rep Med 5(9), 101712.
Garcia-Morena D, Fernandez-Cantos MV, Lopez Escalera S, Lok J, Iannone V, Cancellieri P, Maathuis W, Panagiotou G, Aranzamendi C, El Aidy S, Kolehmainen M, El‑Nezami H, Wellejus A, Kuipers OP (2024) In-vitro influence of specific Bacteroidales strains on gut and liver health related to Metabolic dysfunction-associated fatty liver disease. Probiotics Antimicrob Proteins [Epub ahead of print]
Hedin KA, Mirhakkak MH, Vaaben TH, Sands C, Pedersen M, Baker A, Vazquez-Uribe R, Schäuble S, Panagiotou G#, Wellejus A#, Sommer MOA# (2024) Saccharomyces boulardii enhances anti-inflammatory effectors and AhR activation via metabolic interactions in probiotic communities. ISME Journal 18(1), wrae212.
Heilig L, Fariha N, Trinks N, Aimanianda V, Wong SSW, Fontaine T, Terpitz U, Strobel L, Lemauff F, Sheppard D, Schaeuble S, Kurzai O, Hünniger K, Weiss E, Vargas M, Howell PL, Panagiotou G, Wurster S, Einsele H, Löffler J (2024) CD56-mediated activation of human natural killer cells is triggered by Aspergillus fumigatus galactosaminogalactan. PLOS Pathog 20(6), e1012315.

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