Prof. Dr. med. Marie von Lilienfeld-Toal
Phone: +49 3641 532-1720 Fax: +49 3641 532-2720 Email: email@example.com
- Tumour and infection immunology
- Epidemiology of infections of von Infektionen immunosuppressed patients
- Clinical diagnostic and therapeutical studies
|2014||Deputy head of the Nationales Referenzzentrum für invasive Pilzinfektionen|
|2013||W2-professorship in infection research in haematology and oncology, medical faculty, Friedrich-Schiller University Jena|
|2010||Habilitation in internal medicine, Rheinische Friedrich-Wilhelms University Bonn|
|2008-2013||Senior physician in the dept. haematology / oncology (med. clinic III), University Hospital, Bonn|
|2007-2008||EBMT Fellowship Bone Marrow Transplantation Programme, Leeds, UK|
|2007||Acceptance of the priority area haematology / oncology|
|2006||Specialist in internal diseases|
|2003-2004||Gerok fellowship within the BonFor funding programme, medical faculty Bonn|
|1999-2007||Doctor in practical training (AiP) /assistant physician in internal medicine, University Hospital Bonn|
|1999||PhD in clinical pharmacology, „magna cum laude“, medical faculty, Rheinische Friedrich-Wilhelms University Bonn|
|1998||Staatsexamen (state examination) human medicine|
Awards · Appointments · Scientific Activities
|Since 2013||Member of the ethics commission, medical faculty of the FSU Jena|
|Since 2013||Board member of the working group dealing with infections in haematology and oncology (AGIHO) of the Deutsche Gesellschaft für Hämatologie und internistische Onkologie (DGHO)|
|Since 2008||Member of the AGIHO|
|2008-2010||Assistant lecturer at the medical clinic III of the University Hospital Bonn|
|2002-2006||Member of the statutes commission of the medical faculty of the Rheinische Friedrich-Wilhelms University Bonn|
|2009||Best abstract DGHO|
|Since 2004||Assessor of several magazines|
(2020) Human mucosal-associated invariant T cells respond to Mucorales species in a MR1-dependent manner. Med Mycol , myaa103.
(2020) Frailty impairs the feasibility of induction therapy but not of maintenance therapy in elderly myeloma patients: final results of the German Maintenance Study (GERMAIN). J Cancer Res Clin Oncol 146(3), 749-759.
(2020) Frequency of infections in 948 MPN patients: a prospective multicenter patient-reported pilot study. Leukemia 34(7), 1949-1953.
(2020) Evidence-based management of COVID-19 in cancer patients: Guideline by the Infectious Diseases Working Party (AGIHO) of the German Society for Haematology and Medical Oncology (DGHO). Eur J Cancer 140, 86-104.
(2020) Long-term follow-up of Cladribine, high-dose Cytarabine, and Idarubicin as salvage treatment for relapsed acute myeloid leukemia and literature review. Eur J Haematol 104(6), 538-545.
(2020) Caring for older adults with multiple myeloma during the COVID-19 Pandemic: Perspective from the international forum for optimizing care of older adults with myeloma. J Geriatr Oncol 11(5), 764-768.
(2020) Detection of community-acquired respiratory viruses in allogeneic stem-cell transplant recipients and controls-A prospective cohort study. Transpl Infect Dis 22(6), e13415.
(2020) Treatment of invasive fungal diseases in cancer patients-Revised 2019 recommendations of the infectious diseases working party (AGIHO) of the German Society of Hematology and Oncology (DGHO). Mycoses 63(7), 653-682.
(2020) COVID-19 in cancer patients: clinical characteristics and outcome-an analysis of the LEOSS registry. Ann Hematol [Epub ahead of print]
(2020) Human neutrophils produce antifungal extracellular vesicles against Aspergillus fumigatus. mBio 11(2), e00596-20.
(2020) Community-acquired respiratory viruses in oncology: Lessons to be learnt from the SARS-CoV-2 pandemic. Oncol Res Treat 43(6), 262-263.
(2020) Frequently asked questions regarding SARS-CoV-2 in cancer patients-recommendations for clinicians caring for patients with malignant diseases. Leukemia 34(6), 1487-1494. (Review)
(2019) The risk of infections in multiple myeloma before and after the advent of novel agents: a 12-year survey. Ann Hematol 98(3), 713-722.
(2019) Controlling intestinal colonization of high-risk haematology patients with ESBL-producing Enterobacteriaceae: a randomized, placebo-controlled, multicentre, Phase II trial (CLEAR). J Antimicrob Chemother 74(7), 2065-2074.
(2019) Measuring phagocytosis of Aspergillus fumigatus conidia by human leukocytes using flow cytometry. J Vis Exp (154),
(2019) Fast and quantitative evaluation of human leukocyte interaction with Aspergillus fumigatus conidia by flow cytometry. Cytometry A 95(3), 332-338.
(2019) Continuous high dosing of lenalidomide in relapsed, refractory or older newly diagnosed acute myeloid leukemia patients not suitable for other treatment options - results from a phase I study. Haematologica 104(2), e63-e64.
(2019) MAIT cell activation by fungal pathogens. Methods Mol Biol 2098, 167-177.
(2019) Management of sepsis in neutropenic cancer patients: 2018 guidelines from the Infectious Diseases Working Party (AGIHO) and Intensive Care Working Party (iCHOP) of the German Society of Hematology and Medical Oncology (DGHO). Ann Hematol 98(5), 1051-1069.
(2019) Das Deutsche Pilz-Keratitis-Register: Erste Ergebnisse einer multizentrischen Erhebung [The german keratomycosis registry: Initial results of a multicenter survey]. Ophthalmologe 116(10), 957-966.
(2019) Invasive fungal infection. Dtsch Arztebl Int 116(16), 271-278.
(2019) Standardized monitoring of cytomegalovirus-specific immunity can improve risk stratification of recurrent cytomegalovirus reactivation after hematopoietic stem cell transplantation. Haematologica [Epub ahead of print]
(2018) Human MAIT cells are rapidly activated by Aspergillus spp. in an APC-dependent manner. Eur J Immunol 48(10), 1698-1706.
(2018) Anti-infective vaccination strategies in patients with hematologic malignancies or solid tumors-Guideline of the Infectious Diseases Working Party (AGIHO) of the German Society for Hematology and Medical Oncology (DGHO). Ann Oncol 29(6), 1354-1365.
(2018) Diagnosis of invasive fungal diseases in haematology and oncology: 2018 update of the recommendations of the infectious diseases working party of the German society for hematology and medical oncology (AGIHO). Mycoses 61(11), 796-813.
(2018) Challenges in infectious diseases for haematologists. Oncol Res Treat 41(6), 406-410.
(2017) Screening and contact precautions - A survey on infection control measures for multidrug-resistant bacteria in German university hospitals. Antimicrob Resist Infect Control 6, 37.
(2017) Safety issues and management of toxicities associated with new treatments for multiple myeloma. Expert Rev Hematol 10(3), 193-205. (Review)
(2017) Diagnosis and empirical treatment of fever of unknown origin (FUO) in adult neutropenic patients: guidelines of the Infectious Diseases Working Party (AGIHO) of the German Society of Hematology and Medical Oncology (DGHO). Ann Hematol 96(11), 1775-1792.
(2017) Influenza virus infections in patients with malignancies -- characteristics and outcome of the season 2014/15. A survey conducted by the Infectious Diseases Working Party (AGIHO) of the German Society of Haematology and Medical Oncology (DGHO). Eur J Clin Microbiol Infect Dis 36(3), 565-573.
(2017) Primary propPrimary prophylaxis of invasive fungal infections in patients with haematological malignancies: 2017 update of the recommendations of the Infectious Diseases Working Party (AGIHO) of the German Society for Haematology and Medical Oncology. Ann Hematol [Epub ahead of print]
(2017) Measurement of piperacillin plasma concentrations in cancer patients with suspected infection. Infection 45(5), 629-636.
(2017) Fusarium Keratitis in Germany. J Clin Microbiol 55(10), 2983-2995.
(2016) Outcome of empirical or targeted antifungal therapy after antifungal prophylaxis in febrile neutropenia. Ann Hematol 95(6), 1001-1009.
(2016) Case report: false positive elevated serum-galactomannan levels after autologous hematopoietic stem cell transplantation caused by oral nutritional supplements. Clin Case Rep. 4(5), 505-508.
(2016) Community acquired respiratory virus infections in cancer patients-Guideline on diagnosis and management by the Infectious Diseases Working Party of the German Society for haematology and Medical Oncology. Eur J Cancer 67, 200-212.
(2015) Comparison of antibiotic prophylaxis with cotrimoxazole/colistin (COT/COL) versus ciprofloxacin (CIP) in patients with acute myeloid leukemia. Support Care Cancer 23(5), 1321-1329.
(2015) Antiviral prophylaxis in patients with solid tumours and haematological malignancies--update of the Guidelines of the Infectious Diseases Working Party (AGIHO) of the German Society for Hematology and Medical Oncology (DGHO). Ann Hematol 94(9), 1441-1450.
(2015) Polymorphisms of Toll-like receptors (TLR2 and TLR4) are associated with the risk of infectious complications in acute myeloid leukemia. Genes Immun 16(1), 83-88.
(2015) Efficacy of antifungal prophylaxis with oral suspension posaconazole during induction chemotherapy of acute myeloid leukemia. J Cancer Res Clin Oncol 141(9), 1661-1668.
(2014) Treatment with lenalidomide induces immunoactivating and counter-regulatory immunosuppressive changes in myeloma patients. Clin Exp Immunol 177(2), 439-453.
(2014) Management of sepsis in neutropenic patients: 2014 updated guidelines from the Infectious Diseases Working Party of the German Society of Hematology and Medical Oncology (AGIHO). Ann Hematol 93(7), 1083-1095.
(2014) Tigecycline in febrile neutropenic patients with haematological malignancies: a retrospective case documentation in four university hospitals. Infection 42(1), 97-9104.
(2014) A multicentre cohort study on colonization and infection with ESBL-producing Enterobacteriaceae in high-risk patients with haematological malignancies. J Antimicrob Chemother 69(12), 3387-3392.
(2013) Transient and fully reversible leukocytosis in a myelodysplastic syndrome patient upon initiation of azacitidine treatment. Ann Hematol 92(11), 1577-1579.
(2013) Mixed response to ipilimumab in a melanoma patient with brain metastases: case report and review of the literature. Case Rep Oncol 6(1), 229-235.
(2013) Clinical impact of DNMT3A mutations in younger adult patients with acute myeloid leukemia: results of the AML Study Group (AMLSG). Blood 121(23), 4769-4777.
(2013) Retinoic acid and arsenic trioxide for acute promyelocytic leukemia. N Engl J Med 369(2), 111-121.
(2013) Successful management of Candida krusei monoarthritis after allo-SCT. Bone Marrow Transplant 48(12), 1585-1586.
(2013) Primary prophylaxis of bacterial infections and Pneumocystis jirovecii pneumonia in patients with hematological malignancies and solid tumors: guidelines of the Infectious Diseases Working Party (AGIHO) of the DGHO. Ann Hematol 92(4), 433-442.
(2013) Secondary genetic lesions in acute myeloid leukemia with inv(16) or t(16;16): a study of the German-Austrian AML Study Group (AMLSG). Blood 121(1), 170-177.
(2012) Intermediate intensity conditioning regimen containing FLAMSA, treosulfan, cyclophosphamide, and ATG for allogeneic stem cell transplantation in elderly patients with relapsed or high-risk acute myeloid leukemia. Ann Hematol 91(1), 47-55.
(2012) Diagnosis of chronic disseminated candidosis from liver biopsies by a novel PCR in patients with haematological malignancies. Clin Microbiol Infect 18(10), 1010-1016.
(2012) TET2 mutations in acute myeloid leukemia (AML): results from a comprehensive genetic and clinical analysis of the AML study group. J Clin Oncol 30(12), 1350-1357.
(2012) Monosomal karyotype in adult acute myeloid leukemia: prognostic impact and outcome after different treatment strategies. Blood 119(2), 551-558.
(2012) TP53 alterations in acute myeloid leukemia with complex karyotype correlate with specific copy number alterations, monosomal karyotype, and dismal outcome. Blood 119(9), 2114-2121.
(2012) Novel treatment concepts for graft-versus-host disease. Blood 119(1), 16-25.
(2011) Plerixafor with and without chemotherapy in poor mobilizers: results from the German compassionate use program. Bone Marrow Transplant 46(8), 1045-1052.
(2011) The impact of therapy-related acute myeloid leukemia (AML) on outcome in 2853 adult patients with newly diagnosed AML. Blood 117(7), 2137-2145.
(2011) Monitoring of minimal residual disease in NPM1-mutated acute myeloid leukemia: a study from the German-Austrian acute myeloid leukemia study group. J Clin Oncol 29(19), 2709-2716.
(2011) Management of sepsis in neutropenic patients: guidelines from the infectious diseases working party of the German Society of Hematology and Oncology. Ann Oncol 22(5), 1019-1029.
(2011) Clinically defined chemotherapy-associated bowel syndrome predicts severe complications and death in cancer patients. Haematologica 96(12), 1855-1860.