Natural products from microbes associated with insects.
(2016) Natural products from microbes associated with insects. Beilstein J Org Chem 12, 314-327.
Here we review discoveries of secondary metabolites from microbes associated with insects. We mainly focus on natural products, where the ecological role has been at least partially elucidated, and/or the pharmaceutical properties evaluated, and on compounds with unique structural features. We demonstrate that the exploration of specific microbial–host interactions, in combination with multidisciplinary dereplication processes, has emerged as a successful strategy to identify novel chemical entities and to shed light on the ecology and evolution of defensive associations.
doi: 10.3762/bjoc.12.34 PMID: 26977191