Recent highlights of biosynthetic studies on marine natural products.

Amiri Moghaddam J, Jautzus T, Alanjary M, Beemelmanns C (2021) Recent highlights of biosynthetic studies on marine natural products. Org Biomol Chem 19(1), 123-140. (Review) PubMed Open Access PDF Code

Abstract

Marine bacteria are excellent yet often underexplored sources of structurally unique bioactive natural products. In this review we cover the diversity of marine bacterial biomolecules and highlight recent studies on structurally novel natural products. We include different compound classes and discuss the latest progress related to their biosynthetic pathway analysis and engineering: examples range from fatty acids over terpenes to PKS, NRPS and hybrid PKS-NRPS biomolecules.

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doi: 10.1039/d0ob01677b PMID: 33216100