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(2018) Precursor-directed Diversification of Cyclic Tetrapeptidic Pseudoxylallemycins ChemBioChem 19(21), 2307-2311.
(2018) Streptococcus pneumoniae from patients with hemolytic uremic syndrome binds human plasminogen via the surface protein PspC and uses plasmin to damage human endothelial cells. J Infect Dis 217(3), 358-370.
(2017) A tale of four kingdoms - isoxazolin-5-one- and 3-nitropropanoic acid-derived natural products Natural Product Reports 34(4), 343-360.
(2017) Isolation, biosynthesis and chemical modifications of rubterolones A–F, rare tropolone alkaloids from Actinomadura sp. 5-2 Chem. Eur J 23(39), 9338-9345.
(2017) Arylmethylamino steroids as antiparasitic agents. Nat Commun 8, 14478.
(2017) Antitubercular and Cytotoxic Chlorinated seco-Cyclohexenes from Uvaria alba. J Nat Prod 80(12), 3319-3323.
(2017) Age-related macular degeneration associated polymorphism rs10490924 in ARMS2 results in deficiency of a complement activator J Neuroinflammation 14(1), 4.
(2016) Pseudoxylallemycins A-F, cyclic tetrapeptides with rare allenyl modifications isolated from Pseudoxylaria sp. X802: A competitor of fungus-growing termite cultivars. Org Lett 18, 3338-3341.
(2016) Bipiperidine conjugates as soluble sugar surrogates in DNA-intercalating antiproliferative polyketides. Chem Commun (Camb) 52(27), 4894-4897.
(2015) Genetic engineering activates biosynthesis of aromatic fumaric acid amides in the human pathogen Aspergillus fumigatus. Appl Environ Microbiol 81, 1594-1600.
(2015) Harnessing enzymatic promiscuity in myxochelin biosynthesis for the production of 5-lipoxygenase inhibitors. ChemBioChem 16, 2445-2450.
(2015) Myxochelins target human 5-lipoxygenase. J Nat Prod 78(2), 335-338.
(2015) Plant pathogenic anaerobic bacteria use aromatic polyketides to access aerobic territory. Science 350(6261), 670-674.
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(2015) Targeting the intersubunit cavity of Plasmodium falciparum glutathione reductase by a novel natural inhibitor: Computational and experimental evidence Int J Biochem Cell Biol 61, 72-80.
(2014) Cytotoxic and antifungal activities of melleolide antibiotics follow dissimilar structure-activity relationships. Phytochemistry 105, 101-108.
(2014) Melleolides induce rapid cell death in human primary monocytes and cancer cells. Bioorg Med Chem 22, 3856-3861.
(2014) Biosynthesis of the Halogenated Mycotoxin Aspirochlorine in Koji Mold Involves a Cryptic Amino Acid Conversion. Angew Chem Int Ed Engl 53, 13409-13413.
(2014) Maturity-related changes in venom toxicity of the freshwater stingray Potamotrygon leopoldi. Toxicon 92, 97-101.
(2014) Virulent strain of Lichtheimia corymbifera shows increased phagocytosis by macrophages as revealed by automated microscopy image analysis. Mycoses 57(Suppl. 3), 56-66, */⁺authors contributed equally.
(2014) Tetrahydroxanthene-1,3(2H)-dione Derivatives from Uvaria valderramensis. J Nat Prod 77(12), 2711-2715.
(2014) Structure and Biosynthetic Assembly of Gulmirecins, Macrolide Antibiotics from the Predatory Bacterium Pyxidicoccus fallax. Chem Eur J 20, 15933-15940.
(2014) Injury-induced biosynthesis of methyl-branched polyene pigments in a white-rotting basidiomycete J Nat Prod 77, 2658-2663.
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(2013) Novel type II fatty acid biosynthesis (FAS II) inhibitors as multistage antimalarial agents. ChemMedChem 8(3), 442-461.
(2013) Bimodular peptide synthetase SidE produces fumarylalanine in the human pathogen Aspergillus fumigatus. Appl Environ Microbiol 79, 6670-6676.
(2013) Rational design of an apoptosis-inducing photoreactive DNA intercalator. Angew Chem Int Ed Engl 52(24), 6185-6189.
(2013) Synthetic remodeling of the chartreusin pathway to tune antiproliferative and antibacterial activities. J Am Chem Soc 135(46), 17408-17416.
(2012) Neuraminidase inhibitor susceptibility of swine influenza A viruses isolated in Germany between 1981 and 2008. Med Microbiol Immunol 201(1), 61-72.
(2012) Cytotoxic alkaloids from Fusarium incarnatum associated with the mangrove tree Aegiceras corniculatum. J Nat Prod 75(4), 617-621.
(2012) Photochemical oxazole-nitrile conversion downstream of rhizoxin biosynthesis and its impact on antimitotic activity. Org Biomol Chem 10(30), 5756-5759.
(2011) 2-Acylamino-5-chlorobenzophenones with enhanced selectivity towards malaria parasites. Eur J Med Chem 46(4), 1331-1342.
(2011) Assessing oxazole bioisosteres as mutasynthons on the rhizoxin assembly line. Chembiochem 12(15), 2284-2288.
(2011) Antiproliferative effects of ester- and amide-functionalized rhizoxin derivatives. ChemMedChem 6(11), 1998-2001.
(2011) Cytotoxic pheofungins from an engineered fungus impaired in posttranslational protein modification. Angew Chem Int Ed Engl 50(42), 9843-9847.
(2011) Two induced fungal polyketide pathways converge into antiproliferative spiroanthrones. Chembiochem 12(12), 1836-1839.
(2011) Conidial dihydroxynaphthalene melanin of the human pathogenic fungus Aspergillus fumigatus interferes with the host endocytosis pathway. Front Microbiol / Fungi and their interactions 2, 96.
(2011) Secretome analysis of Aspergillus fumigatus reveals Asp-hemolysin as a major secreted protein. Int J Med Microbiol 301(7), 602-611.
(2010) Botryorhodines A-D, antifungal and cytotoxic depsidones from Botryosphaeria rhodina, an endophyte of the medicinal plant Bidens pilosa. Phytochemistry 71(1), 110-116.
(2010) Pitucamycin: structural merger of a phenoxazinone with an epoxyquinone antibiotic. J Nat Prod 73(9), 1461-1464.
(2010) Aspernidine A and B, prenylated isoindolinone alkaloids from the model fungus Aspergillus nidulans. J Antibiot (Tokyo) 63(7), 375-377.
(2010) Exploiting enzymatic promiscuity to engineer a focused library of highly selective antifungal and antiproliferative aureothin analogues. J Am Chem Soc 132(30), 10407-10413.
(2009) Synthesis and pharmacological activities of some sesquiterpene quinones and hydroquinones. Bioorg Med Chem 17(4), 1422-1427.
(2009) Isoflavones with unusually modified B-rings and their evaluation as antiproliferative agents. Bioorg Med Chem Lett 19(22), 6473-6476.
(2008) Growth of keratinocytes on porous films of poly(3-hydroxybutyrate) and poly(4-hydroxybutyrate) blended with hyaluronic acid and chitosan. J Biomed Mater Res A 85(4), 1072-1081.
(2007) Sanionins: anti-inflammatory and antibacterial agents with weak cytotoxicity from the Antarctic moss Sanionia georgico-uncinata. Prep Biochem Biotechnol 37(4), 343-352.
(2007) Thiosemicarbazones of formyl benzoic acids as novel potent inhibitors of estrone sulfatase. J Med Chem 50(15), 3661-3666.
(2007) Epicoccamides B-D, glycosylated tetramic acid derivatives from an Epicoccum sp. associated with the tree fungus Pholiota squarrosa. J Nat Prod 70(11), 1800-1803.
(2006) The vesicle transport protein Vac1p is required for virulence of Candida albicans. Microbiology 152(Pt 10), 3111-3121.
(2006) Antimitotic rhizoxin derivatives from a cultured bacterial endosymbiont of the rice pathogenic fungus Rhizopus microsporus. J Am Chem Soc 128(35), 11529-11536.
(2005) Biotechnological production and bioactivities of mollisin and two new, structurally related fungal naphthoquinone metabolites. Chem Biodivers 2(8), 1109-1115.