Jakob Franke

Jakob Franke

Biomolecular Chemistry

Publications

Trottmann F, Ishida K, Franke J, Stanišić A, Ishida-Ito M, Kries H, Pohnert G, Hertweck C (2020) Sulfonium acids loaded onto an unusual thiotemplate assembly line construct the cyclopropanol warhead of a Burkholderia virulence factor. Angew Chem Int Ed 59(32), 13511-13515. Details PubMed Open Access PDF

Trottmann F, Franke J, Ishida K, Garcia-Altares M, Hertweck C (2019) A pair of bacterial siderophores releases and traps an intercellular signal molecule: An unusual case of natural nitrone bioconjugation. Angew Chem Int Ed 58(1), 200-204. Details PubMed

Franke J, Hertweck C (2016) Biomimetic Thioesters as Probes for Enzymatic Assembly Lines: Synthesis, Applications, and Challenges. Cell Chem Biol 23(10), 1179-1192. (Review) Details PubMed

Baunach M, Franke J, Hertweck C (2015) Terpenoid biosynthesis off the beaten track: unconventional cyclases and their impact on biomimetic synthesis. Angew. Chem. Int. Ed. 54(9), 2604-2626. Details PubMed

Ding L, Franke J, Hertweck C (2015) Divergolide congeners illuminate alternative reaction channels for ansamycin diversification. Org. Biomol. Chem. 13(6), 1618-1623. Details PubMed

Franke J, Ishida K, Hertweck C (2015) Plasticity of the Malleobactin Pathway and its Impact on Siderophore Action in Human Pathogenic Bacteria. Chemistry 21(22), 8010-8014. Details PubMed

Franke J, Ishida K, Hertweck C (2014) Evolution of siderophore pathways in human pathogenic bacteria. J Am Chem Soc 136(15), 5599-5602. Details PubMed

Pidot S, Ishida K, Cyrulies M, Hertweck C (2014) Discovery of clostrubin, an exceptional polyphenolic polyketide antibiotic from a strictly anaerobic bacterium. Angew Chem Int Ed Engl 53(30), 7856-7859. Details PubMed

Xu Z, Baunach M, Ding L, Peng H, Franke J, Hertweck C (2014) Biosynthetic code for divergolide assembly in a bacterial mangrove endophyte. Chembiochem 15(9), 1274-1279. Details PubMed

Franke J, Ishida K, Ishida-Ito M, Hertweck C (2013) Nitro versus hydroxamate in siderophores of pathogenic bacteria: effect of missing hydroxylamine protection in malleobactin biosynthesis. Angew Chem Int Ed Engl 52(32), 8271-8275. Details PubMed