Dr. Huijuan Guo
Phone: +49 3641 532-1560 Email: email@example.com
- discovery of new bioactive secondary metabolites
- structure elucidation of natural products
- protein identification and analysis
|2009-2014||Doctoral thesis in chemistry at the Max-Planck-Institute for Chemical Ecology, Jena|
|2007–2009||Research assistant at the Institute of Microbiology, Chinese Academy of Sciences, Beijing, P. R. China|
|2005-2007||Master thesis in natural product chemistry, Institute of Microbiology, Chinese Academy of Sciences, Beijing, P. R. China|
|2004-2005||Master study in biochemistry and molecular biology, Graduate University of Chinese Academy of Science, Beijing, P. R. China|
|2000-2004||Bachelor study, Shenyang Agriculture University, Shenyang, P. R. China|
Awards · Appointments · Scientific Activities
|2009-2014||International Leibniz Research School for Microbial and Biomolecular Interactions,
ILRS Jena, Germany
|2009 -||Gesellschaft Chinesischer Chemiker und Chemieingenieuer in der Bundesrepublik
(2020) Gene cluster activation in a bacterial symbiont leads to halogenated angucyclic maduralactomycins and spirocyclic actinospirols. Org Lett 22(7), 2634-2638.
(2020) Structure elucidation of the redox cofactor mycofactocin reveals oligo-glycosylation by MftF. Chem Sci 11, 5182-5190.
(2020) Targeted discovery of tetrapeptides and cyclic polyketide‐peptide hybrids from a fungal antagonist of farming termites. ChemBioChem [Accepted]
(2019) Metabolic pathway rerouting in Paraburkholderia rhizoxinica evolved long-overlooked derivatives of coenzyme F420. ACS Chem Biol 14(9), 2088-2094.
(2019) Tropolone natural products. Nat Prod Rep 36(8), 1137-1155.
(2019) Biosynthesis of the redox cofactor mycofactocin comprises oligoglycosylation by MftF in Mycolicibacterium smegmatis. bioRxiv ,
(2018) Natural products from Actinobacteria associated with fungus-growing termites. Antibiotics 7(3), 83.
(2018) Expanding the rubterolone family: Intrinsic reactivity and directed diversification of PKS‐derived pyrans. Chem Eur J 24(44), 11319-11324.
(2018) Precursor-directed diversification of cyclic tetrapeptidic pseudoxylallemycins. ChemBioChem 19(21), 2307-2311.
(2018) Biosynthesis, synthesis and activities of barnesin A, a NRPS-PKS hybrid produced by an anaerobic Epsilonproteobacterium. ACS Chem Biol 13(8), 1990-1995.
(2017) Isolation, biosynthesis and chemical modifications of rubterolones A–F, rare tropolone alkaloids from Actinomadura sp. 5-2. Chem Eur J 23(39), 9338-9345.
(2017) Natural products and morphogenic activity of γ-Proteobacteria associated with the marine hydroid polyp Hydractinia echinata. Bioorg Med Chem 25(22), 6088-6097.
(2016) Natural products from microbes associated with insects. Beilstein J Org Chem 12, 314-327.
(2016) Pseudoxylallemycins A-F, cyclic tetrapeptides with rare allenyl modifications isolated from Pseudoxylaria sp. X802: A competitor of fungus-growing termite cultivars. Org Lett 18, 3338-3341.
(2016) Draft Genome Sequence of Shewanella sp. P1-14-1, a Bacterial Inducer of Settlement and Morphogenesis in Larvae of the Marine Hydroid Hydractinia Echinata Genome Announc 4(1), e00003-16.
(2015) Genome Sequences of Three Pseudoalteromonas Strains P1-8, P1-11 and P1-30 Isolated from the Marine Hydroid Hydractinia echinata Genome Announc. 3(6), e01380-15.
(2015) Draft Genome Sequences of Six Pseudoalteromonas sp. Strains P1-7a, P1-9, P1-13-1a, P1-16-1b, P1-25 and P1-26, which Induce Larval Settlement and Metamorphosis in Hydractinia echinata Genome Announc. 3(6), e01477-15.
(2014) In vivo Pyro-SIP assessing active gut microbiota of the cotton leafworm, Spodoptera littoralis. PLOS One 9(1), e85948.
(2013) A porin-like protein from oral secretions of Spodoptera littoralis larvae induces defense-related early events in plant leaves. Insect Biochem Mol Biol 43(9), 849-858.
(2009) Ecology-based screen identifies new metabolites from a Cordyceps-colonizing fungus as cancer cell proliferation inhibitors and apoptosis inducers. Cell Prolif 42(6), 838-847.
(2009) Diketopiperazines from the Cordyceps-colonizing fungus Epicoccum nigrum. J Nat Prod 72(12), 2115-2119.
(2009) Trichocladinols A–C, Cytotoxic Metabolites from a Cordyceps-Colonizing Ascomycete Trichocladium opacum Eur J Org Chem 32, 5525-5530.
(2007) Bioactive p-terphenyl derivatives from a Cordyceps-colonizing isolate of Gliocladium sp. J Nat Prod 70(9), 1519-1521.
(2006) Decaspirones F-I, bioactive secondary metabolites from the saprophytic fungus Helicoma viridis. J Nat Prod 69(12), 1672-1675.