Birštonas L, Dallemulle A, López-Berges MS, Jacobsen ID, Offterdinger M, Abt B, Straßburger M, Bauer I, Schmidt O, Sarg B, Lindner H, Haas H, Gsaller F (2020) Multiplex genetic engineering exploiting pyrimidine salvage pathway-based endogenous counterselectable markers. mBio 11(2), e00230-20. Details PubMed Open Access PDF

Gerwien F, Dunker C, Brandt P, Garbe E, Jacobsen ID, Vylkova S (2020) Clinical Candida albicans vaginal isolates and a laboratory strain show divergent behaviors during macrophage interactions. mSphere 5(4), e00393-20. Details PubMed Open Access PDF

Halder LD, Jo EAH, Hasan MZ, Ferreira-Gomes M, Krüger T, Westermann M, Palme DI, Rambach G, Beyersdorf N, Speth C, Jacobsen ID, Kniemeyer O, Jungnickel B, Zipfel PF, Skerka C (2020) Immune modulation by complement receptor 3-dependent human monocyte TGF-ß1-transporting vesicles. Nat Commun 11(1), 2331. Details PubMed Open Access PDF

Machata S, Müller MM, Lehmann R, Sieber S, Panagiotou G, Carvalho A, Cunha C, Lagrou K, Maertens J, Slevogt H, Jacobsen ID (2020) Proteome analysis of bronchoalveolar lavage fluids reveals host and fungal proteins highly expressed during invasive pulmonary aspergillosis in mice and humans. Virulence [Accepted] Details Open Access

Matthias J, Heink S, Picard F, Zeiträg J, Kolz A, Chao YY, Soll D, de Almeida GP, Glasmacher E, Jacobsen ID, Riedel T, Peters A, Floess S, Huehn J, Baumjohann D, Huber M, Korn T, Zielinski CE (2020) Salt generates antiinflammatory Th17 cells but amplifies pathogenicity in proinflammatory cytokine microenvironments. J Clin Invest [Epub ahead of print] Details PubMed Open Access PDF

Ruben S, Garbe E, Mogavero S, Albrecht-Eckardt D, Hellwig D, Häder A, Krüger T, Gerth K, Jacobsen ID, Elshafee O, Brunke S, Hünniger K, Kniemeyer O, Brakhage AA, Morschhäuser J, Hube B, Vylkova S, Kurzai O, Martin R (2020) Ahr1 and Tup1 contribute to the transcriptional control of virulence-associated genes in Candida albicans. mBio 11(2), e00206-20. Details PubMed Open Access PDF

Sprenger M, Hartung TS, Allert S, Wisgott S, Niemiec MJ, Graf K, Jacobsen ID, Kasper L, Hube B (2020) Fungal biotin homeostasis is essential for immune evasion after macrophage phagocytosis and virulence. Cell Microbiol 22(7), e13197. Details PubMed Open Access PDF

Sreekantapuram S*, Lehnert T*, Prauße MT, Berndt A, Berens C, Figge MT**, Jacobsen ID**; *authors contributed equally; **corresponding authors (2020) Dynamic interplay of host and pathogens in an avian whole blood model. Frontiers in Immunology 11, 500. Details PubMed Open Access PDF

Fischer J, Walter C, Tönges A, Aleth H, Jordão MJC, Leddin M, Gröning V, Erdmann T, Lenz G, Roth J, Vogl T, Prinz M, Dugas M, Jacobsen ID, Rosenbauer F (2019) Safeguard function of PU.1 shapes the inflammatory epigenome of neutrophils. Nat Immunol 20(5), 546-558. Details PubMed Open Access PDF

Jacobsen ID (2019) Animal models to study mucormycosis. J Fungi (Basel) 5(2), 27. (Review) Details PubMed Open Access PDF

Klaile E, Müller MM, Zubiría-Barrera C, Brehme S, Klassert TE, Stock M, Durotin A, Nguyen TD, Feer S, Singer BB, Zipfel PF, Rudolphi S, Jacobsen ID, Slevogt H (2019) Unaltered fungal burden and ethality in human CEACAM1-transgenic mice during Candida albicans dissemination and systemic infection. Front Microbiol 10, 2703. Details PubMed Open Access PDF

Kresinsky A, Schnöder TM, Jacobsen ID, Rauner M, Hofbauer LC, Ast V, König R, Hoffmann B, Svensson CM, Figge MT, Hilger I, Heidel FH, Böhmer FD, Müller JP (2019) Lack of CD45 in FLT3-ITD mice results in a myeloproliferative phenotype, cortical porosity, and ectopic bone formation. Oncogene 38(24), 4773-4787. Details PubMed

Krüger W, Vielreicher S, Kapitan M, Jacobsen ID, Niemiec MJ (2019) Fungal-bacterial interactions in health and disease. Pathogens 8(2), 70. (Review) Details PubMed Open Access PDF

Maurer M, Gresnigt MS, Last A, Wollny T, Berlinghof F, Pospich R, Cseresnyes Z, Medyukhina A, Graf K, Gröger M, Raasch M, Siwczak F, Nietzsche S, Jacobsen ID, Figge MT, Hube B, Huber O, Mosig AS (2019) A three-dimensional immunocompetent intestine-on-chip model as in vitro platform for functional and microbial interaction studies. Biomaterials 220, 119396. Details PubMed

Allert S*, Förster TM*, Svensson CM, Richardson JP, Pawlik T, Hebecker B, Rudolphi S, Juraschitz M, Schaller M, Blagojevic M, Morschhäuser J, Figge MT, Jacobsen ID, Naglik JR, Kasper L, Mogavero S, Hube B; *authors contributed equally (2018) Candida albicans-induced epithelial damage mediates translocation through intestinal barriers. mBio 9(3), e00915. Details PubMed Open Access

Beyer R, Jandric Z, Zutz C, Gregori C, Willinger B, Jacobsen ID, Kovarik P, Strauss J, Schüller C (2018) Competition of Candida glabrata against Lactobacillus is Hog1 dependent. Cell Microbiol 20(12), e12943. Details PubMed Open Access

Conrad T, Kniemeyer O, Henkel SG, Krüger T, Mattern DJ, Valiante V, Guthke R, Jacobsen ID, Brakhage AA, Vlaic S, Linde J (2018) Module-detection approaches for the integration of multilevel omics data highlight the comprehensive response of Aspergillus fumigatus to caspofungin. BMC Syst Biol 12(1), 88. Details PubMed Open Access

de Assis LJ, Manfiolli A, Mattos E, Fabri JHTM, Malavazi I, Jacobsen ID, Brock M, Cramer RA, Thammahong A, Hagiwara D, Ries LNA, Goldman GH (2018) Protein kinase a and high-osmolarity glycerol response pathways cooperatively control cell wall carbohydrate mobilization in Aspergillus fumigatus. mBio 9(6), e01952-18. Details PubMed Open Access

Desai PR, Lengeler K, Kapitan M, Janßen SM, Alepuz P, Jacobsen ID, Ernst JF (2018) The 5' untranslated region of the EFG1 transcript promotes its translation to regulate hyphal morphogenesis in Candida albicans. mSphere 3(4), e00280-18. Details PubMed Open Access

Eberl C, Speth C, Jacobsen ID, Hermann M, Hagleitner M, Deshmukh H, Ammann CG, Lass-Flörl C, Rambach G (2018) Candida: Platelet interaction and platelet activity in vitro. J Innate Immun 11(1), 52-62. Details PubMed Open Access

Irmscher S, Döring N, Halder LD, Jo EAH, Kopka I, Dunker C, Jacobsen ID, Luo S, Slevogt H, Lorkowski S, Beyersdorf N, Zipfel PF, Skerka C (2018) Kallikrein cleaves C3 and activates complement. J Innate Immun 10(2), 94-105. Details PubMed Open Access

Kapitan M, Niemiec MJ, Steimle A, Frick JS, Jacobsen ID (2018) Fungi as part of the microbiota and interactions with intestinal bacteria. In: Curr Top Microbiol Immunol (ed.) Current Topics in Microbiology and Immunology 422, pp. 265-301. Springer, Berlin, Heidelberg. (Review) Details PubMed

Luo S, Dasari P, Reiher N, Hartmann A, Jacksch S, Wende E, Barz D, Niemiec MJ, Jacobsen I, Beyersdorf N, Hünig T, Klos A, Skerka C, Zipfel PF (2018) The secreted Candida albicans protein Pra1 disrupts host defense by broadly targeting and blocking complement C3 and C3 activation fragments. Mol Immunol 93, 266-277. Details PubMed

Persyn A, Rogiers O, Brock M, Vande Velde G, Lamkanfi M, Jacobsen ID, Himmelreich U, Lagrou K, Van Dijck P, Kucharíková S (2018) Monitoring of fluconazole and caspofungin activity against in vivo Candida glabrata biofilms by bioluminescence imaging. Antimicrob Agents Chemother 63(2), e01555-18. Details PubMed Open Access PDF

Polke M, Leonhardt I, Kurzai O, Jacobsen ID (2018) Farnesol signalling in Candida albicans - more than just communication. Crit Rev Microbiol 44(2), 230-243. (Review) Details PubMed

Schaarschmidt B, Vlaic S, Medyukhina A, Neugebauer S, Nietzsche S, Gonnert FA, Rödel J, Singer M, Kiehntopf M, Figge MT, Jacobsen ID, Bauer M, Press AT (2018) Molecular signatures of liver dysfunction are distinct in fungal and bacterial infections in mice. Theranostics 8(14), 3766-3780. Details PubMed Open Access PDF

Seyedmousavi S, Bosco SMG, de Hoog S, Ebel F, Elad D, Gomes RR, Jacobsen ID, Martel A, Mignon B, Pasmans F, Piecková E, Rodrigues AM, Singh K, Vicente VA, Wibbelt G, Wiederhold NP, Guillot J (2018) Fungal infections in animals: a patchwork of different situations. Med Mycol 56(suppl_1), 165-187. (Review) Details PubMed Open Access PDF

Templeton SP, Rivera A, Hube B, Jacobsen ID (2018) Editorial: Immunity to human fungal pathogens: Mechanisms of host recognition, protection, pathology, and fungal interference. Front Immunol 9, 2337. Details PubMed Open Access PDF

Zipfel PF, Luo S, Dasari P, Reiher N, Jacobsen I, Beyersdorf N, Klos A, Serka C (2018) Reply to kang and brooks: Comment on the interpretation of binding of Pra1, the fungal immune evasion protein from Candida albicans to the human C3 and on the conformational changes of C3 upon activation: Kang and brooks optimization of biolayer-interfero. Mol Immunol 101, 638-639. Details PubMed

Cunha C, Gonçalves SM, Duarte-Oliveira C, Leite L, Lagrou K, Marques A, Lupiañez CB, Mesquita I, Gaifem J, Barbosa AM, Pinho Vaz C, Branca R, Campilho F, Freitas F, Ligeiro D, Lass-Flörl C, Löffler J, Jurado M, Saraiva M, Kurzai O, Rodrigues F, Castro AG, Silvestre R, Sainz J, Maertens JA, Torrado E, Jacobsen ID, Lacerda JF, Campos A, Carvalho A (2017) IL-10 overexpression predisposes to invasive aspergillosis by suppressing antifungal immunity. J Allergy Clin Immunol 140(3), 867-870.e9. Details PubMed

Halder LD, Abdelfatah MA, Jo EA, Jacobsen ID, Westermann M, Beyersdorf N, Lorkowski S, Zipfel PF, Skerka C (2017) Factor H Binds to Extracellular DNA Traps Released from Human Blood Monocytes in Response to Candida albicans. Front Immunol 7, 671. Details PubMed

Jacobsen ID, Hube B (2017) Candida albicans morphology: still in focus. Expert Rev Anti Infect Ther 15(4), 327-330. (Review) Details PubMed Open Access

Niemiec MJ, Kapitan M, Polke M, Jacobsen ID (2017) Commensal to Pathogen Transition of Candida albicans. In: Elsevier (ed.) Reference Module in Life Sciences 2017 Elsevier. ISBN: 9780128096338. (Review) Details Open Access

Polke M, Jacobsen I (2017) A Flow-assay for Farnesol Removal from Adherent Candida albicans Cultures. Bio-protocol 7(19), e2562. Details Open Access

Polke M, Jacobsen ID (2017) Quorum sensing by farnesol revisited. Curr Genet 63(5), 791-797. (Review) Details PubMed

Polke M, Sprenger M, Scherlach K, Albán-Proaño MC, Martin R, Hertweck C, Hube B, Jacobsen ID (2017) A functional link between hyphal maintenance and quorum sensing in Candida albicans. Mol Microbiol 103(4), 595-617. Details PubMed

Schulze B, Rambach G, Schwartze VU, Voigt K, Schubert K, Speth C, Jacobsen ID (2017) Ketoacidosis alone does not predispose to mucormycosis by Lichtheimia in a murine pulmonary infection model. Virulence 8(8), 1657-1667. Details PubMed

Sobotta K, Bonkowski K, Liebler-Tenorio E, Germon P, Rainard P, Hambruch N, Pfarrer C, Jacobsen ID, Menge C (2017) Permissiveness of bovine epithelial cells from lung, intestine, placenta and udder for infection with Coxiella burnetii. Vet Res 48(1), 23. Details PubMed

Förster TM, Mogavero S, Dräger A, Graf K, Polke M, Jacobsen ID, Hube B (2016) Enemies and brothers in arms: Candida albicans and gram-positive bacteria. Cell Microbiol 18(12), 1709-1715. (Review) Details PubMed

Geib E, Gressler M, Viediernikova I, Hillmann F, Jacobsen ID, Nietzsche S, Hertweck C, Brock M (2016) A non-canonical melanin biosynthesis pathway protects Aspergillus terreus conidia from environmental stress. Cell Chem Biol 23(5), 587-597. Details PubMed

Hebecker B, Vlaic S, Conrad T, Bauer M, Brunke S, Kapitan M, Linde J, Hube B, Jacobsen ID (2016) Dual-species transcriptional profiling during systemic candidiasis reveals organ-specific host-pathogen interactions. Sci Rep 6, 36055. Details PubMed Open Access PDF

Joehnk B, Bayram O, Valerius O, Heinekamp T, Jacobsen ID, Mattern D, Brakhage AA, Braus G (2016) SCF Ubiquitin Ligase F-box Protein Fbx15 Controls Nuclear Co-repressor Localization, Stress Response and Virulence of the Human Pathogen Aspergillus fumigatus PLOS Pathog 12(9), e1005899. Details Open Access PDF

Kroll K, Shekhova E, Mattern DJ, Thywissen A, Jacobsen ID, Strassburger M, Heinekamp T, Shelest E, Brakhage AA, Kniemeyer O (2016) The hypoxia-induced dehydrogenase HorA is required for coenzyme Q10 biosynthesis, azole sensitivity and virulence of Aspergillus fumigatus Mol Microbiol 101(1), 92-108. Details PubMed

Böttcher B, Palige K, Jacobsen ID, Hube B, Brunke S (2015) Csr1/Zap1 maintains zinc homeostasis and influences virulence in Candida dubliniensis but is not coupled to morphogenesis. Eukaryot Cell 14(7), 661-670. Details PubMed Open Access PDF

Brunke S, Quintin J, Kasper L, Jacobsen ID, Richter ME, Hiller E, Schwarzmüller T, d'Enfert C, Kuchler K, Rupp S, Hube B, Ferrandon D (2015) Of mice, flies - and men? Comparing fungal infection models for large-scale screening efforts. Dis Model Mech (8), 473-486. Details PubMed Open Access PDF

Duggan S, Essig F, Hünniger K, Mokhtari Z, Bauer L, Lehnert T, Brandes S, Häder A, Jacobsen ID, Martin R, Figge MT, Kurzai O (2015) Neutrophil activation by Candida glabrata but not Candida albicans promotes fungal uptake by monocytes. Cell Microbiol 17(9), 1259-1276. Details PubMed

Kaerger K, Schwartze VU, Dolatabadi S, Nyilasi I, Kovács SA, Binder U, Papp T, Hoog Sd, Jacobsen ID, Voigt K (2015) Adaptation to thermotolerance in Rhizopus coincides with virulence as revealed by avian and invertebrate infection models, phylogeny, physiological and metabolic flexibility. Virulence 6(4), 395-403. Details PubMed

Polke M, Hube B, Jacobsen ID (2015) Candida survival strategies. Adv Appl Microbiol 91, 139-235. Details PubMed

Brunke S, Seider K, Fischer D, Jacobsen ID, Kasper L, Jablonowski N, Wartenberg A, Bader O, Enache-Angoulvant A, Schaller M, d’Enfert C, Hube B (2014) One small step for a yeast - Microevolution within macrophages renders Candida glabrata hypervirulent due to a single point mutation. PLOS Pathog 10(10), e1004478. Details PubMed Open Access

Hebecker B, Naglik JR, Hube B, Jacobsen ID (2014) Pathogenicity mechanisms and host response during oral Candida albicans infections. Expert Rev Anti Infect Ther 12(7), 867-879. (Review) Details PubMed

Jacobsen ID (2014) Galleria mellonella as a model host to study virulence of Candida. Virulence 5(2), 237-239. Details PubMed

Jacobsen ID, Lüttich A, Kurzai O, Hube B, Brock M (2014) In vivo imaging of disseminated murine Candida albicans infection reveals unexpected host sites of fungal persistence during antifungal therapy. J Antimicrob Chemother 69(10), 2785-2796. Details PubMed

Krljanac B, Weih D, Jacobsen ID, Hu D, Koliesnik I, Reppe K, Witzenrath M, Weih F (2014) NF-κB2/p100 deficiency impairs immune responses to T-cell-independent type 2 antigens. Eur J Immunol 44(3), 662-672. Details PubMed

Kroll K, Pähtz V, Hillmann F, Vaknin Y, Schmidt-Heck W, Roth M, Jacobsen ID, Osherov N, Brakhage AA, Kniemeyer O (2014) Identification of hypoxia-inducible target genes of Aspergillus fumigatus by transcriptome analysis reveals cellular respiration as important contributor to hypoxic survival. Eukaryot Cell 13(9), 1241-1253. Details PubMed

Miramón P, Dunker C, Kasper L, Jacobsen ID, Barz D, Kurzai O, Hube B (2014) A family of glutathione peroxidases contributes to oxidative stress resistance in Candida albicans. Med Mycol 52(3), 223-239. Details PubMed

Otzen C, Bardl B, Jacobsen ID, Nett M, Brock M (2014) Candida albicans utilizes a modified β-oxidation pathway for the degradation of toxic propionyl-CoA. J Biol Chem 289(12), 8151-8169. Details PubMed

Quintin J, Voigt J, van der Voort R, Jacobsen ID, Verschueren I, Hube B, Giamarellos-Bourboulis EJ, van der Meer JW, Joosten LA, Kurzai O, Netea MG (2014) Differential role of NK cells against Candida albicans infection in immunocompetent or immunocompromised mice. Eur J Immunol 44(8), 2405-2414. Details PubMed

Schwartze VU, de A. Santiago ALCM, Jacobsen ID, Voigt K (2014) The pathogenic potential of the Lichtheimia genus revisited: Lichtheimia brasiliensis is a novel, non-pathogenic species. Mycoses 57(Suppl. 3), 128-131. Details PubMed

Schwartze VU, Jacobsen ID (2014) Mucormycoses caused by Lichtheimia species. Mycoses 57(Suppl. 3), 73-78. Details PubMed

Schwartze VU, Winter S, Shelest E, Marcet-Houben M, Horn F, Wehner S, Linde J, Valiante V, Sammeth M, Riege K, Nowrousian M, Kaerger K, Jacobsen ID, Marz M, Brakhage AA, Gabaldón T, Böcker S, Voigt K (2014) Gene expansion shapes genome architecture in the human pathogen Lichtheimia corymbifera: an evolutionary genomics analysis in the ancient terrestrial Mucorales (Mucoromycotina). PLOS Genetics 10(8), e1004496. Details PubMed Open Access

Schwarzmüller T, Ma B, Hiller E, Istel F, Tscherner M, Brunke S, Ames L, Firon A, Green B, Cabral V, Marcet-Houben M, Jacobsen ID, Quintin J, Seider K, Frohner I, Glaser W, Jungwirth H, Bachellier-Bassi S, Chauvel M, Zeidler U, Ferrandon D, Gabaldón T, Hube B, d'Enfert C, Rupp S, Cormack B, Haynes K, Kuchler K (2014) Systematic phenotyping of a large-scale Candida glabrata deletion collection reveals novel antifungal tolerance genes. PLOS Pathog 10(6), e1004211. Details PubMed Open Access

Voigt J, Hünniger K, Bouzani M, Jacobsen ID, Barz D, Hube B, Löffler J, Kurzai O (2014) Human natural killer cells acting as phagocytes against Candida albicans and mounting an inflammatory response that modulates neutrophil antifungal activity. J Infect Dis 209(4), 616-626. Details PubMed

Wartenberg A, Linde J, Martin R, Schreiner M, Horn F, Jacobsen ID, Jenull S, Wolf T, Kuchler K, Guthke R, Kurzai O, Forche A, d'Enfert C, Brunke S, Hube B (2014) Microevolution of Candida albicans in macrophages restores filamentation in a nonfilamentous mutant. PLOS Genet 10(12), e1004824. Details PubMed Open Access

Wilson D, Mayer FL, Miramón P, Citiulo F, Slesiona S, Jacobsen ID, Hube B (2014) Distinct roles of Candida albicans-specific genes in host-pathogen interactions. Eukaryot Cell 13(8), 977-989. Details PubMed

Hennicke F, Grumbt M, Lermann U, Ueberschaar N, Palige K, Böttcher B, Jacobsen ID, Staib C, Morschhäuser J, Monod M, Hube B, Hertweck C, Staib P (2013) Factors supporting cysteine tolerance and sulfite production in Candida albicans. Eukaryot Cell 12(4), 604-613. Details PubMed

Lüttich A, Brunke S, Hube B, Jacobsen ID (2013) Serial passaging of Candida albicans in systemic murine infection suggests that the wild type strain SC5314 is well adapted to the murine kidney. PLOS One 8(5), e64482. Details PubMed Open Access

Otto GP, Ludewig K, Jacobsen ID, Schaarschmidt B, Hube B, Bauer M (2013) Limitation of (1→3)-β-D-glucan monitoring in major elective surgery involving cardiopulmonary bypass. Crit Care 17(3), 437. Details PubMed

Otzen C, Müller S, Jacobsen ID, Brock M (2013) Phylogenetic and phenotypic characterisation of the 3-ketoacyl-CoA thiolase gene family from the opportunistic human pathogenic fungus Candida albicans. FEMS Yeast Res 13(6), 553-564. Details PubMed

Braukmann M, Sachse K, Jacobsen ID, Westermann M, Menge C, Saluz HP, Berndt A (2012) Distinct intensity of host-pathogen interactions in Chlamydia psittaci- and Chlamydia abortus-infected chicken embryos. Infect Immun 80(9), 2976-2988. Details PubMed

Citiulo F, Jacobsen ID, Miramón P, Schild L, Brunke S, Zipfel PF, Brock M, Hube B, Wilson D (2012) Candida albicans scavenges host zinc via Pra1 during endothelial invasion. PLOS Pathog 8(6), e1002777. Details PubMed Open Access

Jacobsen ID, Grosse K, Hube B (2012) Embryonated chicken eggs as alternative infection model for pathogenic fungi. In: Brand AC, MacCallum DM (eds.) Methods in Molecular Biology. Host-fungus interactions. Methods and Protocols. 845, pp. 487-496. Humana Press (Springer). Details PubMed

Jacobsen ID, Wilson D, Wächtler B, Brunke S, Naglik JR, Hube B (2012) Candida albicans dimorphism as a therapeutic target. Expert Rev Anti Infect Ther 10(1), 85-93. (Review) Details PubMed

Mayer FL, Wilson D, Jacobsen ID, Miramón P, Große K, Hube B (2012) The novel Candida albicans transporter Dur31 Is a multi-stage pathogenicity factor. PLOS Pathog 8(3), e1002592. Details PubMed

Mayer FL, Wilson D, Jacobsen ID, Miramón P, Slesiona S, Bohovych IM, Brown AJ, Hube B (2012) Small but crucial: the novel small heat shock protein Hsp21 mediates stress adaptation and virulence in Candida albicans. PLOS One 7(6), e38584. Details PubMed

McCormick A, Jacobsen ID, Broniszewska M, Beck J, Heesemann J, Ebel F (2012) The two-component sensor kinase TcsC and its role in stress resistance of the human-pathogenic mold Aspergillus fumigatus. PLOS One 7(6), e38262-e38262. Details PubMed

Schrödl W, Heydel T, Schwartze VU, Hoffmann K, Grosse-Herrenthey A, Walther G, Alastruey-Izquierdo A, Rodriguez-Tudela JL, Olias P, Jacobsen ID, de Hoog GS, Voigt K (2012) Direct analysis and identification of pathogenic Lichtheimia species by matrix-assisted laser desorption ionization-time of flight analyzer-mediated mass spectrometry. J Clin Microbiol 50(2), 419-427. Details PubMed

Schwartze VU, Hoffmann K, Nyilasi I, Papp T, Vágvölgyi C, de Hoog S, Voigt K, Jacobsen ID (2012) Lichtheimia species exhibit differences in virulence potential. PLOS One 7(7), e40908. Details PubMed

Slesiona S, Gressler M, Mihlan M, Zaehle C, Schaller M, Barz D, Hube B, Jacobsen ID, Brock M (2012) Persistence versus escape: Aspergillus terreus and Aspergillus fumigatus employ different strategies during interactions with macrophages. PLOS One 7(2), e31223-e31223. Details PubMed

Slesiona S, Ibrahim-Granet O, Olias P, Brock M, Jacobsen ID (2012) Murine infection models for Aspergillus terreus pulmonary aspergillosis reveal long-term persistence of conidia and liver degeneration. J Infect Dis 205(8), 1268-1277. Details PubMed

Fendrich V, Schneider R, Maitra A, Jacobsen ID, Opfermann T, Bartsch DK (2011) Detection of precursor lesions of pancreatic adenocarcinoma in PET-CT in a genetically engineered mouse model of pancreatic cancer. Neoplasia 13(2), 180-186. Details PubMed

Jacobsen ID, Grosse K, Berndt A, Hube B (2011) Pathogenesis of Candida albicans infections in the alternative chorio-allantoic membrane chicken embryo model resembles systemic murine infections. PLOS One 6(5), e19741-e19741. Details PubMed

Keller S, Macheleidt J, Scherlach K, Schmaler-Ripcke J, Jacobsen ID, Heinekamp T, Brakhage AA (2011) Pyomelanin formation in Aspergillus fumigatus requires HmgX and the transcriptional activator HmgR but is dispensable for virulence. PLOS One 6(10), e26604. Details PubMed

Martin R, Moran GP, Jacobsen ID, Heyken A, Domey J, Sullivan DJ, Kurzai O, Hube B (2011) The Candida albicans-specific gene EED1 encodes a key regulator of hyphal extension. PLOS One 6(4), e18394. Details PubMed

Olias P, Gruber AD, Hafez HM, Lierz M, Slesiona S, Brock M, Jacobsen ID (2011) Molecular epidemiology and virulence assessment of Aspergillus fumigatus isolates from white stork chicks and their environment. Vet Microbiol 148(2-4), 348-355. Details PubMed

Olias P, Jacobsen ID, Gruber AD (2011) Fungal species identification from avian lung specimens by single hypha laser microdissection and PCR product sequencing. Med Mycol 49(1), 56-61. Details PubMed

Wartenberg D, Lapp K, Jacobsen ID, Dahse HM, Kniemeyer O, Heinekamp T, Brakhage AA (2011) Secretome analysis of Aspergillus fumigatus reveals Asp-hemolysin as a major secreted protein. Int J Med Microbiol 301(7), 602-611. Details PubMed

Behnsen J, Lessing F, Schindler S, Wartenberg D, Jacobsen ID, Thoen M, Zipfel PF, Brakhage AA (2010) Secreted Aspergillus fumigatus protease Alp1 degrades human complement proteins C3, C4, and C5. Infect Immun 78(8), 3585-3594. Details PubMed

Gehrke A, Heinekamp T, Jacobsen ID, Brakhage AA (2010) Heptahelical receptors GprC and GprD of Aspergillus fumigatus are essential regulators of colony growth, hyphal morphogenesis, and virulence. Appl Environ Microbiol 76(12), 3989-3998. Details PubMed

Jacobsen ID, Brunke S, Seider K, Schwarzmüller T, Firon A, d'Enfért C, Kuchler K, Hube B (2010) Candida glabrata persistence in mice does not depend on host immunosuppression and is unaffected by fungal amino acid auxotrophy. Infect Immun 78(3), 1066-1077. Details PubMed

Jacobsen ID, Grosse K, Slesiona S, Hube B, Berndt A, Brock M (2010) Embryonated eggs as an alternative infection model to investigate Aspergillus fumigatus virulence. Infect Immun 78(7), 2995-3006. Details PubMed

Kotz A, Wagener J, Engel J, Routier FH, Echtenacher B, Jacobsen I, Heesemann J, Ebel F (2010) Approaching the secrets of N-glycosylation in Aspergillus fumigatus: characterization of the AfOch1 protein. PLOS One 5(12), e15729-e15729. Details PubMed

Menger B, Vogt PM, Jacobsen ID, Allmeling C, Kuhbier JW, Mutschmann F, Reimers K (2010) Resection of a large intra-abdominal tumor in the Mexican axolotl: a case report. Vet Surg 39(2), 232-233. Details PubMed

Schöbel F, Jacobsen ID, Brock M (2010) Evaluation of lysine biosynthesis as an antifungal drug target: biochemical characterization of Aspergillus fumigatus homocitrate synthase and virulence studies. Eukaryot Cell 9(6), 878-893. Details PubMed

Schrettl M, Beckmann N, Varga J, Heinekamp T, Jacobsen ID, Jöchl C, Moussa TA, Wang S, Gsaller F, Blatzer M, Werner ER, Niermann WC, Brakhage AA, Haas H (2010) HapX-mediated adaption to iron starvation is crucial for virulence of Aspergillus fumigatus. PLOS Pathog 6(9), e1001124-e1001124. Details PubMed

Laube T, Bernet A, Dahse HM, Jacobsen ID, Seifert K (2009) Synthesis and pharmacological activities of some sesquiterpene quinones and hydroquinones. Bioorg Med Chem 17(4), 1422-1427. Details PubMed

Völksch B, Thon S, Jacobsen ID, Gube M (2009) Polyphasic study of plant- and clinic-associated Pantoea agglomerans strains reveals indistinguishable virulence potential. Infect Genet Evol 9(6), 1381-1391. Details PubMed

Wilson D, Thewes S, Zakikhany K, Fradin C, Albrecht A, Almeida R, Brunke S, Grosse K, Martin R, Mayer F, Leonhardt I, Schild L, Seider K, Skibbe M, Slesiona S, Waechtler B, Jacobsen I, Hube B (2009) Identifying infection-associated genes of Candida albicans in the postgenomic era. FEMS Yeast Res 9(5), 688-700. (Review) Details PubMed

Mota Júnior AO, Malavazi I, Soriani FM, Heinekamp T, Jacobsen I, Brakhage AA, Savoldi M, Goldman MH, da Silva Ferreira ME, Goldman GH (2008) Molecular characterization of the Aspergillus fumigatus NCS-1 homologue, NcsA. Mol Genet Genomics 280(6), 483-495. Details PubMed

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