Pierre Stallforth

Dr. Pierre Stallforth

Chemistry of Microbial Communication · Head

Phone: +49 3641 532-1527 Fax: +49 3641 532-2527 Email: pierre.stallforth@leibniz-hki.de

Main Research Areas
  • Chemical ecology of the amobae-bacteria symbiosis
  • Prokaryotic and eukaryotic signal molecules
  • Prokaryotic two-component systems
Curriculum vitae

Professional Career

12/2013 Junior research group leader, Leibniz Institute for Natural Product Research and Infection Biology, (Hans-Knöll-Institute, Jena) 
2/2011-11/2013 Postdoc, Harvard Medical School, Dept. of Biological Chemistry and Molecular Pharmacology, Boston, Supervisor: Prof. Jon Clardy
11/2006-11/2010 Graduate studies (Dr. sc. ETH Zurich), ETH Zurich and Max Planck Institute, colloids and interfaces, biomolecular systems, Berlin supervisors: Prof. Peter H. Seeberger, Prof. Donald Hilvert “synthesis of bacterial carbohydrates and glycolipids for application in novel vaccine srategies”
09/2005-07/2006 Master thesis, University of Oxford supervisor: Prof. David E. Logan “dynamics of a quantum dot in a magnetic field” (1st class)
10/2002-07/2006 MSc studies chemistry, St Edmund Hall, University of Oxford (1st class, being placed 2nd out of 150 students)
06/2002 Abitur (A-levels) at the Paul-Klee-Gymnasium Gersthofen, Germany

Awards · Appointments · Scientific Activities

02/2014  Fellowship of the Daimler and Benz Foundation
06/2012 Feodor Lynen-postdoc fellowship (Humboldt Foundation)
02/2011 Swiss National Fund Postdoc fellowship
06/2007 PhD fellowship, Studienstiftung des deutschen Volkes (German Academic Merit Foundation)
06/2005 Gibbs prize for excellence in the final examination
06/2005-07/2007 Fellowship of the Studienstiftung des deutschen Volkes
2003 and 2004 Turbutt prize for excellence in practical organic chemistry
06/2003-07/2006 University of Oxford, open scholarship
06/2002 Prize for the best Abitur (A-levels) at the Paul-Klee-Gymnaisum

Klapper M, Arp J, Günther M, Stallforth P (2018) The Role of Bacterial Natural Products in Predator Defense Synlett [Accepted] (Review) Details

Arp J, Stallforth P (2017) Rationalizing the Right Ratios. Cell Chem Biol 24(5), 539-541. (Review) Details PubMed

Barnett R, Raszkowski D, Winckler T, Stallforth P (2017) Versatile synthesis of the signaling peptide glorin Beilstein J Org Chem 13, 247-250. Details

Barnett R, Stallforth, P (2017) Natural Products from Social Amoebae Chem Eur J [In press] (Review) Details PubMed

Gallegos-Monterrosa R, Kankel S, Götze S, Barnett R, Stallforth P, Kovács ÁT (2017) Lysinibacillus fusiformis M5 induces increased complexity in Bacillus subtilis 168 colony biofilms via hypoxanthine. J Bacteriol 199(22), e00204-e00217. Details PubMed

Götze S, Herbst-Irmer R, Klapper M, Görls H, Schneider KRA, Barnett R, Burks T, Neu U, Stallforth P (2017) Structure, Biosynthesis, and Biological Activity of the Cyclic Lipopeptide Anikasin ACS Chem Biol [In press] Details PubMed

Adibekian A, Stallforth P (2016) Cutting Edge Chemical Biology: Report from the 2016 International Symposium on Chemical Biology, January 13-15, Geneva, Switzerland. ACS Chem Biol 11(4), 816-820. Details PubMed

Klapper M, Götze S, Barnett R, Willing K, Stallforth P (2016) Bacterial alkaloids prevent amoebal predation. Angew Chem Int Ed Engl 55(31), 8944-8947. Details PubMed Supplement

Braesel J, Götze S, Shah F, Heine D, Tauber J, Hertweck C, Tunlid A, Stallforth P, Hoffmeister D (2015) Three redundant synthetases secure redox-active pigment production in the basidiomycete Paxillus involutus. Chem Biol 22, 1325-1334. Details PubMed

Matthies S, Stallforth P, Seeberger PH (2015) Total Synthesis of Legionaminic Acid as Basis for Serological Studies J Am Chem Soc 137, 2848-2851. Details

Cavallari M, Stallforth P, Kalinichenko A, Rathwell DCK, Gronewold TMA, Adibekian A, Mori L, Landmann R, Seeberger PH, DeLibero G (2014) A semi-synthetic carbohydrate-lipid vaccine that protects against S. pneumoniae in mice Nat Chem Biol 10, 950-956. Details

Stallforth P, Clardy J (2014) Atlas for drug discovery. Proc Natl Acad Sci U S A 111(10), 3655-3656. Details PubMed

Stallforth P, Brock DA, Cantley AM, Tian X, Queller DC, Strassmann JE, Clardy J (2013) A bacterial symbiont is converted from an inedible producer of beneficial molecules into food by a single mutation in the gacA gene. Proc Natl Acad Sci U S A 110(36), 14528-14533. Details PubMed

Stallforth P, Clardy J (2013) X-ray crystallography: One size fits most. Nature 495(7442), 456-457. Details PubMed

Stallforth P, Clardy J (2012) Protein evolution: when two become three. Curr Biol 22(17), R685-R687. Details PubMed

Ohara T, Adibekian A, Esposito D, Stallforth P, Seeberger PH (2010) Towards the synthesis of a Yersinia pestis cell wall polysaccharide: enantioselective synthesis of an L-glycero-D-manno-heptose building block. Chem Commun (Camb) 46(23), 4106-4108. Details PubMed

Pragani R, Stallforth P, Seeberger PH (2010) De novo synthesis of a 2-acetamido-4-amino-2,4,6-trideoxy-D-galactose (AAT) building block for the preparation of a Bacteroides fragilis A1 polysaccharide fragment. Org Lett 12(7), 1624-1627. Details PubMed

Stallforth P, Adibekian A, Seeberger PH (2008) De novo synthesis of a D-galacturonic acid thioglycoside as key to the total synthesis of a glycosphingolipid from Sphingomonas yanoikuyae. Org Lett 10(8), 1573-1576. Details PubMed