Discovery of clostrubines
Shabuer G et al., Science 2015.
The Leibniz-HKI is an internationally leading research institute. Here, some important milestones of our development in recent years are summarised.
Scientific highlights
Scientists at the Leibniz-HKI combine microbial natural product research with infection biology, in particular of human-pathogenic fungi, and use their findings to develop new diagnostic methods and natural product-based anti-infectives.
Function of complement inhibitor ApoE
Yin C et al., Nat Med 2019.
New Candida albicans antigens
Bacher P et al., Cell 2019.
Discovery of Candidalysin, the first toxin of a human-pathogenic fungus
Moyes et al., Nature 2016.
Synergistic effects of natural products
Arp J et al., Proc Natl Acad Sci 2018.
Virulent C. albicans mutant without hyphae formation
Dunker C et al., Nat Commun 2021.
Cooperative defense of bacteria against amoeba
Götze S et al., Chem Sci 2019.
High-throughput droplet microfluidics
Mahler L et al., eLife 2021.
Large collaborative research projects
The Leibniz-HKI is partner and initiator of large collaborative projects, i.e.:
Individual projects
Scientists of the Leibniz-HKI are successful in acquiring third party funding for research projects, e.g.:
