Gianni Panagiotou

Prof. Dr. Gianni Panagiotou

Microbiome Dynamics · Head +49 3641 532-1759

Curriculum vitae

Main Research Areas
  • Medical & Environmental Metagenomics: human, mice, marine, plants;
  • Systems Biology: -omics integration, chemical-protein & protein-protein interaction networks; 
  • Synthetic Biology: genome-scale metabolic modelling, design of probiotics, discovery of postbiotics


Bruch A*, Lazarova V*, Krueger T, Schaeuble S, Kelani AA, Lehenberger P, Kniemeyer O, Panagiotou G, Blango MG (2024) Mod5 mediates a molecular trade-off between optimal gene expression and antifungal resistance. bioRxiv [Preprint]
Chen J, Lu RS, Diaz-Canestro C,Song E, Jia X, Liu Y, Wang C, Cheung CKY, Panagiotou G#, Xu A# (2024) Distinct changes in serum metabolites and lipid species in the onset and progression of NAFLD in obese Chinese. Comput Struct Biotechnol J 23(2024), 791-800.
Garcia-Morena D, Fernandez-Cantos MV, Lopez Escalera S, Lok J, Iannone V, Cancellieri P, Maathuis W, Panagiotou G, Aranzamendi C, El Aidy S, Kolehmainen M, El‑Nezami H, Wellejus A, Kuipers OP (2024) In-vitro influence of specific Bacteroidales strains on gut and liver health related to Metabolic dysfunction-associated fatty liver disease. Probiotics Antimicrob Proteins [Epub ahead of print]
Li H*, Zhang L*, Li J*, Wu Q*, Qian L, He J, Ni Y, Kovatcheva-Datchary P, Yuan R, Liu S, Shen L, Zhang M, Sheng B, Li P, Kang K, Wu L, Fang Q, Long X, Liu X, Wang X, Li Y, Ye Y, Ye J, Bao Y, Zhao Y, Xu G, Panagiotou G#, Xu A#, and Jia W# (2024) Resistant starch intake facilitates weight loss in humans by reshaping the gut microbiota. Nat Metab (Feb 26), 1-20.
Peng H, Schmiederer J, Chen X, Panagiotou G, Kries H# (2024) Controlling substrate- and stereospecificity of condensation domains in nonribosomal peptide synthetases. ACS Chem Bio [In press]
Brandt P*, Mirhakkak MH*, Wagner L, Driesch D, Möslinger A, Fänder P, Schäuble S, Panagiotou G, Vylkova S# (2023) High-throughput profiling of Candida auris isolates reveals clade-specific metabolic differences. Microbiol Spectr 11(3), e0049823.
Chao YY, Puhach A, Frieser D, Arunkumar M, Lehner L, Seeholzer T, Garcia-Lopez A, van der Wal M, Fibi-Smetana S, Dietschmann A, Sommermann T, Ćiković T, Taher L, Gresnigt MS, Vastert SJ, van Wijk F, Panagiotou G, Krappmann D, Groß O, Zielinski CE (2023) Human TH17 cells engage gasdermin E pores to release IL-1α on NLRP3 inflammasome activation. Nat Immunol 24(2), 295-308.
Chen J*, Leal Siliceo S*, Ni Y, Nielsen HB, Xu A, Panagiotou G (2023) Identification of robust and generalizable biomarkers for microbiome-based stratification in lifestyle interventions. Microbiome 11(1), 178.
Csader S*, Chen X*, Leung H*, Männistö V, Pentikäinen H, Tauriainen MM, Savonen K, El-Nezami H, Schwab U#, Panagiotou G# (2023) Gut ecological networks reveal associations between bacteria, exercise and clinical profile in non-alcoholic fatty liver disease patients. mSystems 8(5), e0022423.
Häder A#, Schäuble S#, Gehlen J, Thielemann N, Buerfent BC, Schüller V, Hess T, Wolf T, Schröder J, Weber M, Hünniger K, Löffler J, Vylkova S, Panagiotou G, Schumacher J, Kurzai O (2023) Pathogen-specific innate immune response patterns are distinctly affected by genetic diversity. Nat Commun 14(1), 3239.