Prof. Dr. Gianni Panagiotou

Microbiome Dynamics · Head +49 3641 532-1759 gianni.panagiotou@leibniz-hki.de

Curriculum vitae

Main Research Areas

Medical & Environmental Metagenomics: human, mice, marine, plants;
Systems Biology: -omics integration, chemical-protein & protein-protein interaction networks;
Synthetic Biology: genome-scale metabolic modelling, design of probiotics, discovery of postbiotics

Publications

Mirhakkak MH^*, Chen X^*, Heinekamp T, Sae-Ong T, Xu LL, Ni Y, Kurzai O, Barber AE, Brakhage AA, Boutin S, Schäuble S^#, Panagiotou G^# (2023) Genome-scale Metabolic modeling of Aspergillus fumigatus strains reveals growth dependencies on the lung microbiome. Nat Commun 14(1), 4369.

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Ni Y^*, Qian L^*, Leal Siliceo S^*, Long X^*, Nychas E, Liu Y, Ismaiah MJ, Leung H, Zhang L, Gao Q, Wu Q, Zhang Y, Jia Xi, Liu S, Yuan R, Zhou L, Wang X, Li Q, Zhao Y, El-Nezami H, Xu A, Xu G^#, Li H^#, Panagiotou G^#, Jia W^# (2023) Resistant starch decreases intrahepatic triglycerides in NAFLD patients via gut microbiome alterations. Cell Metab 35(9), 1530-1547.

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Patumcharoenpol P, Kingkaw A, Nakphaichit M, Chatchatee P, Suratannon N^#, Panagiotou G, Vongsangnak W^# (2023) Exploring longitudinal gut microbiome towards metabolic functional changes associated in atopic dermatitis in early childhood. Biology (Basel) 12(9), 1262-1277.

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Refisch A^#, Sen ZD, Klassert TE, Busch A, Besteher B, Danyeli LV, Helbing D, Schulze-Späte U, Stallmach A, Bauer M, Panagiotou G, Jacobsen ID, Slevogt H, Opel N, Walter M (2023) Microbiome and immuno-metabolic dysregulation in patients with major depressive disorder with atypical clinical presentation. Neuropharmacology 235, 109568. (Review)

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Schruefer S, Pschibul A, Wong SSW, Sae-Ong T, Wolf T, Schäuble S, Panagiotou G, Brakhage AA, Aimanianda V, Kniemeyer O, Ebel F (2023) Distinct transcriptional responses to fludioxonil in Aspergillus fumigatus and its ΔtcsC and Δskn7 mutants reveal a crucial role for Skn7 in the cell wall reorganizations triggered by this antifungal. BMC Genomics 24(1), 684.

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Seelbinder B^#, Lohinai Z^*, Vazquez-Uribe R, Brunke S, Chen X, Mirhakkak M, Lopez-Escalera S, Dome B, Megyesfalvi Z, Berta J, Galffy G, Dulka E, Wellejus A, Weiss GJ, Bauer M, Hube B, Sommer MOA, Panagiotou G (2023) Candida expansion in the gut of lung cancer patients associates with an ecological signature that supports growth under dysbiotic conditions. Nat Commun 14(1), 2673.

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Allert S, Schulz D, Kämmer P, Großmann P, Wolf T, Schäuble S, Panagiotou G, Brunke S, Hube B (2022) From environmental adaptation to host survival: Attributes that mediate pathogenicity of Candida auris. Virulence 13(1), 191-214.

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Alonso-Roman R, Last A, Mirhakkak MH, Sprague JL, Möller L, Großmann P, Graf K, Gratz R, Mogavero S, Vylkova S, Panagiotou G, Schäuble S, Hube B, Gresnigt MS (2022) Lactobacillus rhamnosus colonisation antagonizes Candida albicans by forcing metabolic adaptations that compromise pathogenicity. Nat Commun 13(1), 3192.

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Brandt P, Gerwien F, Wagner L, Krüger T, Ramírez-Zavala B, Mirhakkak MH, Schäuble S, Kniemeyer O, Panagiotou G, Brakhage AA, Morschhäuser J, Vylkova S (2022) Candida albicans SR-like protein kinases regulate different cellular processes: Sky1 is involved in control of ion homeostasis, while Sky2 is important for dipeptide utilization. Front Cell Infect Microbiol 12, 850531.

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