(2023)
Ncs2* mediates in vivo virulence of pathogenic yeast through sulphur modification of cytoplasmic transfer RNA.
Nucleic Acids Res 51(15),
8133-8149.

Dr Sascha Brunke
Microbial Pathogenicity Mechanisms · Deputy head of department +49 3641 532-1222 sascha.brunke@leibniz-hki.dePublications
(2023)
Ecological niche-inspired genome mining leads to the discovery of crop-protecting nonribosomal lipopeptides featuring a transient amino acid building block.
J Am Chem Soc 145(4),
2342-2353.
(2023)
"Under Pressure" - How fungi evade, exploit, and modulate cells of the innate immune system.
Semin Immunol 66,
101738.
(Review)
(2023)
Selection of cross-reactive T cells by commensal and food-derived yeasts drives cytotoxic TH1 cell responses in Crohn's disease.
Nat Med 29(10),
2602-2614.
(2023)
Antigen specificity and cross-reactivity drive functionally diverse anti-Aspergillus fumigatus T cell responses in cystic fibrosis.
J Clin Invest 133(5),
e161593.
(2023)
Candida expansion in the gut of lung cancer patients associates with an ecological signature that supports growth under dysbiotic conditions.
Nat Commun 14(1),
2673.
(2023)
"We've got to get out"-Strategies of human pathogenic fungi to escape from phagocytes.
Mol Microbiol
[Epub ahead of print] (Review)
(2022)
From environmental adaptation to host survival: Attributes that mediate pathogenicity of Candida auris.
Virulence 13(1),
191-214.
(2022)
Synthesis and evaluation of novel furanones as biofilm inhibitors in opportunistic human pathogens.
Eur J Med Chem 242,
114678.
(2022)
Candidalysin is the hemolytic factor of Candida albicans.
Toxins (Basel) 14(12),
874.