Triggering cryptic natural product biosynthesis in microorganisms.

Scherlach K, Hertweck C (2009) Triggering cryptic natural product biosynthesis in microorganisms. Org Biomol Chem 7(9), 1753-1760. PubMed

Abstract

Natural products from microorganisms are a crucial source for novel therapeutics. Even so, it seems that many valuable compounds are overlooked when culturing microbes under standardized laboratory conditions. Many biosynthesis genes remain silent and such

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doi: 10.1039/b821578b PMID: 19590766