Hydractinia and Their Symbionts

Microbes associated with marine invertebrates are well-known to harbor an enormous biosynthetic potential. We combine new bioassays, genome sequencing and mining strategies to identify the encoded secondary metabolites with unique chemical scaffolds and potential pharmaceutical application.

Publications

Rischer M, Lee SR, Eom HJ, Park HB, Vollmers J, Kaster AK, Shin JH, Oh DC, Kim KH, Beemelmanns C* (2018) Spirocyclic cladosporicin A and cladosporiumins I and J from a Hydractinia-associated Cladosporium sphaerospermum SW67 Org.Chem. Front. [Epub ahead of print] Details Open Access

Rischer M, Raguz L, Guo H, Keiff F, Diekert G, Goris T, Beemelmanns C (2018) Biosynthesis, Synthesis and Activities of Barnesin A, a NRPS-PKS Hybrid Produced by an Anaerobic Epsilonproteobacterium ACS Chem Biol 13(8), 1990-1995. Details PubMed

Wichard T, Beemelmanns C (2018) Role of chemical mediators in aquatic interactionas across the prokaryote eukaryote boundary J Chem Ecol [Accepted] (Review) Details PubMed

Guo H, Rischer M, Sperfeld M, Weigel C, Menzel KD, Clardy J, Beemelmanns C (2017) Natural products and morphogenic activity of γ-Proteobacteria associated with the marine hydroid polyp Hydractinia echinata. Bioorg Med Chem 25(22), 6088-6097. Details PubMed Code

Rischer M, Klassen J, Wolf T, Guo H, Shelest E, Clardy J, Beemelmanns C (2016) Draft Genome Sequence of Shewanella sp. P1-14-1, a Bacterial Inducer of Settlement and Morphogenesis in Larvae of the Marine Hydroid Hydractinia Echinata Genome Announc 4(1), e00003-16. Details PubMed

Klassen JL, Rischer M, Wolf T, Guo H, Shelest E, Clardy J, Beemelmanns C (2015) Genome Sequences of Three Pseudoalteromonas Strains P1-8, P1-11 and P1-30 Isolated from the Marine Hydroid Hydractinia echinata Genome Announc. 3(6), e01380-15. Details PubMed

Klassen JL, Wolf T, Rischer M, Guo H, Shelest E, Clardy J, Beemelmanns C (2015) Draft Genome Sequences of Six Pseudoalteromonas sp. Strains P1-7a, P1-9, P1-13-1a, P1-16-1b, P1-25 and P1-26, which Induce Larval Settlement and Metamorphosis in Hydractinia echinata Genome Announc. 3(6), e01477-15. Details PubMed

Staff

Dr. Christine Beemelmanns

Head

Phone: +49 3641 532-1525 Email: christine.beemelmanns@leibniz-hki.de

Claudia Franke

Technical Assistent

Phone: +49 3641 532-1151 Email: claudia.franke@leibniz-hki.de

Dr. Huijuan Guo

Post Doc

Phone: +49 3641 532-1560 Email: huijuan.guo@leibniz-hki.de

Dr. Theresa Jautzus

Postdoc

Email: theresa.jautzus@leibniz-hki.de

Robin Mendler

Bachelor

Dr. rer. nat Jamshid Amiri Moghaddam

Postdoc

Phone: +49 3641 532-1593 Email: jamshid.amiri.moghaddam@leibniz-hki.de

Chia-Chi Peng

PhD student

Email: Chia-chi_Peng@leibniz-hki.de

Maja Rischer

PhD student

Phone: +49 3641 532-1575 Email: maja.rischer@leibniz-hki.de