Dr. Felix Trottmann

Alumni

Publications

Dumjahn L, Wein P, Molloy EM, Scherlach K, Trottmann F, Meisinger P, Judd LM, Pidot SJ, Stinear TP, Richter I, Hertweck C (2025) Dual-use virulence factors of the opportunistic pathogen Chromobacterium haemolyticum mediate haemolysis and colonization. bioRxiv [Preprint]
Dörner S, Trottmann F, Jordan P, Bartels B, Rogge K, Werz O, Hertweck C, Hoffmeister D (2024) The fatal mushroom neurotoxin muscarine is released from a harmless phosphorylated precursor upon cellular injury. Angew Chem Int Ed 63(52), e202417220.
Ehinger FJ, Scherlach K, Trottmann F, Fiedler J, Richter I, Hertweck C (2024) A catch-release strategy for the genomics-driven discovery of antiproliferative furan-functionalized peptides. Angew Chem Int Ed , e202421760.
Fiedler J, Trottmann F, Ishida K, Mie II, Hertweck C (2024) Direct a-hydroxy acid loading onto a bacterial thiotemplate assembly line via a multienzyme gateway. Angew Chem Int Ed 63(30), e202405165.
Kries H, Trottmann F, Hertweck C (2024) Novel biocatalysts from specialized metabolism. Angew Chem Int Ed 63(4), e202309284. (Review)
Little RF, Trottmann F, Hashizume H, Preissler M, Unger S, Sawa R, Kries H, Pidot S, Igarashi M, Hertweck C (2024) Analysis of the valgamicin biosynthetic pathway reveals a general mechanism for cyclopropanol formation across diverse natural product scaffolds. ACS Chem Biol 19(3), 660-668.
Schäfer E, Seibold PS, Bartram S, Trottmann F, Hänsch V, Gressler M, Chadeayne A, Hertweck C, O'Connor S, Hoffmeister D (2023) A "Magic Mushroom" multi-product sesquiterpene synthase. ChemBioChem 24(21), e202300511.
Trottmann F, Fiedler J, Ishida K, Ishida-Ito M, Little RF, Hertweck C (2023) Bacterial pathogen channels medium-sized fatty acids into malleicyprol biosynthesis. ACS Chem Biol 18(7), 1557-1563.
Lenz C, Dörner S, Trottmann F, Hertweck C, Sherwood A, Hoffmeister D (2022) Assessment of bioactivity-modulating pseudo-ring formation in psilocin and related tryptamines. ChemBioChem 23(13), e202200183.
Little R, Trottmann F, Preissler M, Hertweck C (2022) An intramodular thioesterase domain catalyses chain release in the biosynthesis of a cytotoxic virulence factor. RSC Chem Biol 3(9), 1121-1128.