(2022)
Yellow polyketide pigment suppresses premature hatching in social amoeba.
Proc Natl Acad Sci U S A 119(43),
e2116122119.
Dr. Lars Regestein
Bio Pilot Plant · Research Group Leader HoWi Bio Pilot Plant · Deputy head of Department +49 3641 532-1279 lars.regestein@leibniz-hki.deCurriculum vitae
Main Research Areas
- Development and characterization of online measurement techniques
- Viscous biological systems
- Mixed culture processes
Professional Career
| Since 12/2017 | Deputy Department Head of Bio Pilot Plant, HKI |
| 2015 - 2017 | Group Leader, AVT Biochemical Engineering, RWTH Aachen University |
| 2014 – 2015 | Research Professor at Western University, London, Ontario, Kanada |
| 2012 - 2014 | Group Leader , AVT Biochemical Engineering, RWTH Aachen University |
| 2007 – 2011 | PhD Studies, RWTH Aachen University |
| 2000 – 2007 | Diploma Studies in Process Technology, TU Dresden |
Awards · Appointments · Scientific Activities
| 2014 - 2015 | Theodore von Kármán Fellowship (RWTH Aachen University) |
| 2014 - 2015 | Western Fellowship (Western University, London, Ontario) |
| Since 2017 | Membership Zukunftsforum Biotechnologie (DECHEMA) |
| Since 2014 | Membership BioFuelNet Canada |
| Since 2007 | Membership Bioverfahrenstechnik Dresden e. V. |
Publications
(2022)
The potential of amoeba-based processes for natural product syntheses.
Curr Opin Biotechnol 77,
102766.
(Review)
(2022)
Scale-up of an amoeba-based process for the production of the cannabinoid precursor olivetolic acid.
Microb Cell Fact 21(1),
217.
(2022)
Engineering the amoeba Dictyostelium discoideum for biosynthesis of a cannabinoid precursor and other polyketides.
Nat Biotechnol 40(5),
751-758.
(2022)
Scalable downstream method for the cyclic lipopetidejagaricin.
Eng Life Sci 22(12),
811-817.
(2022)
Foam-free production of the rhamnolipid precursor 3-(3-hydroxyalkanoyloxy) alkanoic acid (HAA) by Pseudomonas putida.
Disc Chem Engin 2(8),
(2021)
Structural and functional analysis of bacterial sulfonosphingolipids and rosette-inducing factor 2 (RIF-2) by mass spectrometry-guided isolation and total synthesis.
Chemistry 28(8),
e202103883.
(2021)
Lignin aromatics to PHA polymers: Nitrogen and oxygen are the Key factors for Pseudomonas.
ACS Sustain Chem Eng 9(31),
10579-10590.
(2021)
Measurement techniques to resolve and control population dynamics of mixed-culture processes.
Trends Biotechnol 39(10),
1093-1109.
(Review)
(2021)
Host nutrition-based approach for biotechnological production of the antifungal cyclic lipopeptide jagaricin.
J Biotechnol 336,
1-9.
