Christine Skerka

Alumni

Publications

Perie L, Herr SM, Ghebreslassie T, Wulf S, Löschmann I, Sekulic A, Suwandi A, Maier AKB, Rowlin L, Jungnickel B, Schäuble S, Panagiotou G, Strauß O, Wiech T, Zipfel PF, Zipfel SLH, Skerka C (2026) Deletion of the mouse homolog of human FHR1 (muFHR1) alleviates Atherosclerosis in ApoE-/- mice. Int J Med Sci 23(2), 585-599.
Sekulic A, Herr SM, Mulfaul K, Pompös IM, Winkler S, Dietrich C, Obermayer B, Mullins RF, Conrad T, Zipfel PF, Sennlaub F, Skerka C, Strauß O (2025) Factor-H-related protein 1 (FHR1), a promotor of para-inflammation in age-related macular degeneration. J Neuroinflammation 22(1), 173.
Zipfel PF, Skerka C (2025) Why is C5a inflammatory complement inhibition not enough to improve C3 glomerulopathy? J Am Soc Nephrol 36(3), 345-347.
Perie L*, Stippa S*, Saffer C*, Hartmann A, Mörglin M, Zipfel SLH, Figge MT, Wiech T, Skerka C, Zipfel PF# (2024) Unique target binding by the C-terminal region of FHR1 provides a new perception of aHUS pathology. Front Hematol 3,
Busch C, Rau S, Sekulic A, Perie L, Huber C, Gehrke M, Joussen AM, Zipfel PF, Wildner G, Skerka C, Strauß O (2023) Increased plasma level of terminal complement complex in AMD patients: potential functional consequences for RPE cells. Front Immunol 14, 1200725.
Halder LD, Babych S, Palme DI, Mansouri-Ghahnavieh E, Ivanov L, Ashonibare V, Langenhorst D, Prusty B, Rambach G, Wich M, Trinks N, Blango MG, Kornitzer D, Terpitz U, Speth C, Jungnickel B, Beyersdorf N, Zipfel PF, Brakhage AA, Skerka C (2022) Candida albicans induces cross-kingdom miRNA trafficking in human monocytes to promote fungal growth. mBio 13(1), e0356321.
Shahraz A, Lin Y, Mbroh J, Winkler J, Liao H, Lackmann M, Bungartz A, Zipfel PF, Skerka C, Neumann H (2022) Low molecular weight polysialic acid binds to properdin and reduces the activity of the alternative complement pathway. Sci Rep 12(1), 5818.
Stea ED, Skerka C, Accetturo M, Pesce F, Wiech T, Hartmann A, Pontrelli P, Castellano G, Zipfel PF, Gesualdo L (2022) Novel FHR2 variants in atypical haemolytic uremic syndrome: a case study of translational medicine approach in renal transplantation. Front Immunol 13, 1008294.
Zipfel PF, Skerka C (2022) From magic bullets to modern therapeutics: Paul Ehrlich, the German immunobiologist and physician who coined the term ‘Complement’. Mol Immunol 150, 90-98. (Review)
Dasari P, Nordengrün M, Vilhena C, Steil L, Abdurrahman G, Surmann K, Dhople V, Lahrberg J, Bachert C, Skerka C, Völker U, Bröker BM, Zipfel PF (2021) The protease SplB of Staphylococcus aureus targets host complement components and inhibits complement-mediated bacterial opsonophagocytosis. J Bacteriol 204(1), e0018421.