Modelling of invasive A. fumigatus infections in the human lung

In co-operation with PD Dr. A. Mosig (Jena University Hospital), our group established a microfluidic lung-on-a-chip model to analyse invasive Aspergillus infections. The 3D model allows simulation of a clinical tissue infection and thus enables investigation of the immune response as well as drug testing. In addition, a cooperation with the group Applied Systems Biology of Prof. Dr. M.T. Figge (HKI) allows quantitative analyses of growth behavior.

Scheme of the model with application of labelled conidia (upper panel) and growth of invasive hyphae (lower panel).
Susann Hartung

Dr. Susann Hartung

Postdoc

Phone: +49 3641 532-1061 Email: susann.hartung@leibniz-hki.de

Mai Hoang

Mai Hoang

Ph.D. student

Phone: +49 3641 532-1541 Email: mai.hoang@leibniz-hki.de

Svenja Grau

Master student

Phone: +49 3641 532-1538 Email: svenja.grau@leibniz-hki.de

Noreen Schuck

Noreen Schuck

HiWi

Phone: +49 3641 532-0405 Email: noreen.schuck@leibniz-hki.de