Paper of the month: DGHM has chosen recent publication by Steffi & Toni
The German Society for Hygiene and Microbiology (DGHM) has chosen the recently published paper, written by our PhD students Steffi and Toni, for the "Paper of the month":
Allert S, Förster TM (first authors), Svensson CM, Richardson JP, Pawlik T, Hebecker B, Rudolphi S, Juraschitz M, Schaller M, Blagojevic M, Morschhäuser J, Figge MT, Jacobsen ID, Naglik JR, Kasper L, Mogavero S, Hube B (2018) Candida albicans-induced epithelial damage mediates translocation through intestinal barriers. mBio 9(3), e00915-18. [OpenAccess] [PubMed]
C. albicans is a successful commensal colonizer of human mucosal surfaces, but can also cause systemic infections by translocation from the gut niche into the bloodstream. This publication is the first detailed study of C. albicans translocation across the intestinal epithelial barrier. It is shown that fungal translocation is associated with hyphae formation and necrotic epithelial damage, depending on the recently identified peptide toxin Candidalysin.
Congratulations, Steffi & Toni!