GRN2SBML: automated encoding and annotation of inferred gene regulatory networks complying with SBML.

Vlaic S, Hoffmann B, Kupfer P, Weber M, Dräger A (2013) GRN2SBML: automated encoding and annotation of inferred gene regulatory networks complying with SBML. Bioinformatics 29(17), 2216-2217.

Abstract

GRN2SBML automatically encodes gene regulatory networks derived from several inference tools in systems biology markup language. Providing a graphical user interface, the networks can be annotated via the simple object access protocol (SOAP)-based application programming interface of BioMart Central Portal and minimum information required in the annotation of models registry. Additionally, we provide an R-package, which processes the output of supported inference algorithms and automatically passes all required parameters to GRN2SBML. Therefore, GRN2SBML closes a gap in the processing pipeline between the inference of gene regulatory networks and their subsequent analysis, visualization and storage.

Leibniz-HKI-Authors

Bianca Hoffmann
Peter Kupfer
Sebastian Vlaic
Michael Weber

Identifier

doi: 10.1093/bioinformatics/btt370

PMID: 23803467