(2021)
The protease SplB of Staphylococcus aureus targets host complement components and inhibits complement-mediated bacterial opsonophagocytosis.
J Bacteriol
[Epub ahead of print]
Prof. Dr. Peter F. Zipfel
Infection Biology · Head International Leibniz Research School · Speaker +49 3641 532-1301 peter.zipfel@leibniz-hki.deCurriculum vitae
Main Research Areas
- Immune escape of human pathogenic micro-organisms
- Infection-associated function of the complement system
- Genetic susceptibility for infections
Professional Career
| Since 2000 | Professor for infection biology, Friedrich-Schiller-University Jena (FSU Jena) |
| Since 2000 | Head of the department infection biology, Leibniz-Institute for Natural Product Research and Infection Biology – Hans-Knöll-Institute Jena |
| 1999 | Nontenured professor, University Hamburg |
| 1993 | Habilitation in immunology and molecular biology, University Hamburg |
| 1989-2000 | Group head at the Bernhard-Nocht-Institute for tropical medicine Hamburg |
| 1989 | Visiting associate, Laboratory of Immunoregulation, National Institutes of Health, Bethesda, Maryland, USA |
| 1985-1988 | Postdoc, Laboratory of Immunoregulation, National Institutes of Health, Bethesda, Maryland, USA, funded by the German Academic Exchange Service (DAAD) |
| 1984 | PhD as Dr. rer. nat., University Bremen |
| 1980-1985 | Research assistant, University Bremen |
| 1980 | Diploma in biology, University Bremen |
Awards · Appointments · Scientific Activities
| Since 2009 | Member at the editorial board of molecular immunology, frontiers in innate immunity |
| 2009 | Excellence award from the Deutsche Gesellschaft für Hygiene und Mikrobiologie |
| Since 2008 | Representative of the graduate school International Leibniz Research School for Microbial and Biomolecular Interactions (ILRS) |
| 2008 | EFIS lecture award of the European Federation of Immunological Societies |
| Since 2007 | Principal investigator of the excellence graduate school Jena School for Microbial Communication (JSMC) |
| 2007 | Heinz Spitzbart award of the European Society for Infectious Diseases in Obstetrics and Gynaecology (ESIDOG) |
| Since 2006 | Principal investigator of the graduate school International Leibniz Research School for Microbial and Biomolecular Interactions (ILRS) |
| 2007-2011 | President of the European Complement Network |
| 2005 – 2012 | Board member of the European Complement Network |
| 2004 | Thuringian research award |
| Since 2002 | Deputy Director of the Leibniz-Institute for Natural Product Research and Infection Biology – Hans-Knöll-Institute Jena |
| Since 2000 | Project leader for infection biology, L2 |
| 1999-2001 | Member at the editorial board of experimental and clinical immunology, thrombosis and haemostasis, section editor molecular immunology Member of the European Working Party on the Genetics of Complement mediated Kidney Diseases, Deutsche Gesellschaft für Hygiene und Mikrobiologie (DGHM), Deutsche Gesellschaft für Immunologie, Gesellschaft für Genetik, Gesellschaft für Nephrologie |
Publications
(2021)
Molecular analyses identifies new domains and structural differences among Streptococcus pneumoniae immune evasion proteins PspC and Hic.
Sci Rep 11(1),
1701.
(2021)
Complement catalyzing glomerular diseases.
Cell Tissue Res 385(2),
355-370.
(Review)
(2020)
A genome-wide association study identifies key modulators of complement factor h binding to malondialdehyde-epitopes.
Proc Nat Acad Sci USA 117(18),
9942-9951.
(2020)
Long-term data on two sisters with C3GN due to an identical, homozygous CFH mutation and autoantibodies.
Clini Nephrol 94(4),
197-206.
(2020)
Immune modulation by complement receptor 3-dependent human monocyte TGF-ß1-transporting vesicles.
Nat Commun 11(1),
2331.
(2020)
Complement in hemolysis and thrombosis-related diseases.
Front Immunol 11,
1212.
(Review)
(2020)
How does complement affect hematological malignancies: From basic mechanisms to clinical application.
Front Immunol 11,
593610.
(Review)
(2020)
In situ visualization o C3/C5 convertases to differentiate complement activation.
Kidney Int Rep 5(6),
927-930.
(2020)
Acquisition of human plasminogen facilitates complement evasion by the malaria parasite Plasmodium falciparum.
Eur J Immunol 51(2),
490-493.
