Prof. Dr. Peter F. Zipfel

Infection Biology · Head International Leibniz Research School · Speaker +49 3641 532-1301 peter.zipfel@leibniz-hki.de

Curriculum vitae

Main Research Areas

Immune escape of human pathogenic micro-organisms
Infection-associated function of the complement system
Genetic susceptibility for infections

Professional Career

Since 2000	Professor for infection biology, Friedrich-Schiller-University Jena (FSU Jena)
Since 2000	Head of the department infection biology, Leibniz-Institute for Natural Product Research and Infection Biology – Hans-Knöll-Institute Jena
1999	Nontenured professor, University Hamburg
1993	Habilitation in immunology and molecular biology, University Hamburg
1989-2000	Group head at the Bernhard-Nocht-Institute for tropical medicine Hamburg
1989	Visiting associate, Laboratory of Immunoregulation, National Institutes of Health, Bethesda, Maryland, USA
1985-1988	Postdoc, Laboratory of Immunoregulation, National Institutes of Health, Bethesda, Maryland, USA, funded by the German Academic Exchange Service (DAAD)
1984	PhD as Dr. rer. nat., University Bremen
1980-1985	Research assistant, University Bremen
1980	Diploma in biology, University Bremen

Awards · Appointments · Scientific Activities

Since 2009	Member at the editorial board of molecular immunology, frontiers in innate immunity
2009	Excellence award from the Deutsche Gesellschaft für Hygiene und Mikrobiologie
Since 2008	Representative of the graduate school International Leibniz Research School for Microbial and Biomolecular Interactions (ILRS)
2008	EFIS lecture award of the European Federation of Immunological Societies
Since 2007	Principal investigator of the excellence graduate school Jena School for Microbial Communication (JSMC)
2007	Heinz Spitzbart award of the European Society for Infectious Diseases in Obstetrics and Gynaecology (ESIDOG)
Since 2006	Principal investigator of the graduate school International Leibniz Research School for Microbial and Biomolecular Interactions (ILRS)
2007-2011	President of the European Complement Network
2005 – 2012	Board member of the European Complement Network
2004	Thuringian research award
Since 2002	Deputy Director of the Leibniz-Institute for Natural Product Research and Infection Biology – Hans-Knöll-Institute Jena
Since 2000	Project leader for infection biology, L2
1999-2001	Member at the editorial board of experimental and clinical immunology, thrombosis and haemostasis, section editor molecular immunology Member of the European Working Party on the Genetics of Complement mediated Kidney Diseases, Deutsche Gesellschaft für Hygiene und Mikrobiologie (DGHM), Deutsche Gesellschaft für Immunologie, Gesellschaft für Genetik, Gesellschaft für Nephrologie

Publications

Benz MR, Schmid H, Heinen S, Lange-Sperandio B, Hoefele J, Sitter T, Zipfel PF, Weber LT (2011) Different factor H-related protein patterns in siblings with typical hemolytic uremic syndrome. Pediatr Nephrol 26(8), 1345-1347.

Details

Bradley DT, Zipfel PF, Hughes AE (2011) Complement in age-related macular degeneration: a focus on function. Eye (Lond) 25(6), 683-693.

Details

Burmester A, Shelest E, Glöckner G, Heddergott C, Schindler S, Staib P, Heidel A, Felder M, Petzold A, Szafranski K, Feuermann M, Pedruzzi I, Priebe S, Groth M, Winkler R, Li W, Kniemeyer O, Schroeckh V, Hertweck C, Hube B, White TC, Platzer M, Guthke R, Heitman J, Wöstemeyer J, Zipfel PF, Monod M, Brakhage AA (2011) Comparative and functional genomics provide insights into the pathogenicity of dermatophytic fungi. Genome Biol 12(1), R7.

Details

Büttner-Mainik A, Parsons J, Jérôme H, Hartmann A, Lamer S, Schaaf A, Schlosser A, Zipfel PF, Reski R, Decker EL (2011) Production of biologically active recombinant human factor H in Physcomitrella. Plant Biotechnol J 9(3), 373-383.

Details

Chen Q, Müller D, Rudolph B, Hartmann A, Kuwertz-Bröking E, Wu K, Kirschfink M, Skerka C, Zipfel PF (2011) Combined C3b and factor B autoantibodies and MPGN type II. N Engl J Med 365(24), 2340-2342.

Details

Hallström T, Nordström T, Tan TT, Manolov T, Lambris JD, Isenman DE, Zipfel PF, Blom AM, Riesbeck K (2011) Immune evasion of Moraxella catarrhalis involves ubiquitous surface protein A-dependent C3d binding. J Immunol 186(5), 3120-3129.

Details

Lauer N, Mihlan M, Hartmann A, Schlötzer-Schrehardt U, Keilhauer C, Scholl HP, Charbel Issa P, Holz F, Weber BH, Skerka C, Zipfel PF (2011) Complement regulation at necrotic cell lesions is impaired by the age-related macular degeneration-associated factor-H His402 risk variant. J Immunol 187(8), 4374-4383.

Details

Losse J, Svobodová E, Heyken A, Hube B, Zipfel PF, Józsi M (2011) Role of pH-regulated antigen 1 of Candida albicans in the fungal recognition and antifungal response of human neutrophils. Mol Immunol 48(15-16), 2135-2143.

Details

Luo S, Blom AM, Rupp S, Hipler UC, Hube B, Skerka C, Zipfel PF (2011) The pH-regulated antigen 1 of Candida albicans binds the human complement inhibitor C4b-binding protein and mediates fungal complement evasion. J Biol Chem 286(10), 8021-8029.

Details

Mihlan M, Blom AM, Kupreishvili K, Lauer N, Stelzner K, Bergström F, Niessen HW, Zipfel PF (2011) Monomeric C-reactive protein modulates classic complement activation on necrotic cells. FASEB J 25(12), 4198-4210.

Details