(2016)
A non-canonical peptide synthetase adenylates 3-methyl-2-oxovaleric acid for auriculamide biosynthesis.
Beilstein J Org Chem 12,
2766-2770.
Curriculum vitae
Main Research Areas
- Quinone synthetases and related enzymes
- Polyketide synthases of basidiomycetes
- Biosynthesis of psilocybin
- Natural products of the genus Psilocybe
Professional Career
| 2014- | Full Professor for Pharmaceutical Microbiology, FSU Jena and HKI Jena |
| 2009-2014 | Associate Professor for Pharmaceutical Biology, FSU Jena and head of the associated department Pharmaceutical Biology at the HKI Jena |
| 2007-2009 | Assistant Professor (tenure track) University of Minnesota, Saint Paul, MN, USA |
| 2008 | Habilitation in Pharmaceutical Biology and Biotechnology, Albert-Ludwigs-University Freiburg |
| 2004-2007 | Junior Group Leader, Institute for Pharmacy, Albert-Ludwigs-University, Freiburg |
| 2002-2004 | Postdoc, University of Wisconsin, Madison, WI, USA (DFG-fellowship) |
| 2002 | Dr. rer. nat., Faculty of Chemistry and Pharmacy, Albert-Ludwigs-University, Freiburg |
| 1998 | Diploma in biology at the Eberhard-Karls-University, Tübingen |
Awards · Appointments · Scientific Activities
| Since 2020 | Head of the Institute for Pharmacy, FSU Jena |
| 2016-2019 | Dean for Study Affairs in the Faculty of Biology and Pharmacy, FSU Jena |
| 2013-2016 | Scientific advisory board, Vereinigung für Allgemeine und Angewandte Mikrobiologie (VAAM). |
Publications
(2016)
Active-site engineering expands the substrate profile of the Basidiomycete L-tryptophan decarboxylase CsTDC.
ChemBioChem 17,
132-136.
(2016)
An iterative O-methyltransferase catalyzes 1,11-dimethylation of Aspergillus fumigatus fumaric acid amides.
ChemBioChem 17,
1813-1817.
(2016)
Globally distributed root endophyte Phialocephala subalpina links pathogenic and saprophytic lifestyles.
BMC Genomics 17,
1015.
(2016)
Unexpected metabolic versatility in a combined fungal fomannoxin/vibralactone biosynthesis.
J Nat Prod 79,
1407-1414.
(2016)
Ectomycorrhizal fungi decompose soil organic matter using oxidative mechanisms adapted from saprotrophic ancestors.
New Phytol 209,
1705-1719.
(2016)
Involutin is a Fe3+ reductant secreted by the ectomycorrhizal fungus Paxillus involutus during fenton-based decomposition of organic matter.
Appl Environ Microbiol 81,
8427-8433.
(2016)
Bacteria induce pigment formation in the basidiomycete Serpula lacrymans.
Environ Microbiol 18,
5218-5227.
(2016)
A fivefold parallelized biosynthetic process secures chlorination of Armillaria mellea (honey mushroom) toxins.
Appl Environ Microbiol 82,
1196-1204.
(2015)
Three redundant synthetases secure redox-active pigment production in the basidiomycete Paxillus involutus.
Chem Biol 22,
1325-1334.
