
Dr. habil. Matthias Brock
Microbial Biochemistry and Physiology Now: The University of Nottingham
(2017) A highly conserved basidiomycete peptide synthetase produces a trimeric hydroxamate siderophore. Appl Environ Microbiol 83(21), e01478. Details PubMed
(2017) Encapsulation of antifungals in micelles protects Candida albicans during gall-bladder infection. Front Microbiol 8, 117. Details PubMed Open Access
(2017) Candida albicans Hap43 domains are required under iron starvation but not excess. Front Microbiol 8, 2388. Details PubMed Open Access
(2016) A non-canonical melanin biosynthesis pathway protects Aspergillus terreus conidia from environmental stress. Cell Chem Biol 23(5), 587-597. Details PubMed
(2016) Widespread inter- and intra-Ddmain horizontal gene transfer of d-amino acid metabolism enzymes in eukaryotes. Front Microbiol 7, 2001. Details PubMed Open Access
(2015) Bringing light into the dark site of infection. Cytometry Part A [Epub ahead of print] (Review) Details PubMed
(2015) A new high-performance heterologous fungal expression system based on regulatory elements from the Aspergillus terreus terrein gene cluster. Front Microbiol 6, 184. Details PubMed
(2015) Phytotoxin production in Aspergillus terreus is regulated by independent environmental signals. eLife 4, e07861. Details PubMed Open Access PDF
(2014) Histidine degradation via an aminotransferase increases the nutritional flexibility of Candida glabrata. Eukaryot Cell 13(6), 758-765. Details PubMed
(2014) In vivo imaging of disseminated murine Candida albicans infection reveals unexpected host sites of fungal persistence during antifungal therapy. J Antimicrob Chemother 69(10), 2785-2796. Details PubMed
(2014) Candida albicans utilizes a modified β-oxidation pathway for the degradation of toxic propionyl-CoA. J Biol Chem 289(12), 8151-8169. Details PubMed
(2014) Illuminating Fungal Infections with Bioluminescence PLOS Pathog. 10(7), e1004179. (Review) Details PubMed
(2014) Regulatory networks controlling nitrogen sensing and uptake in Candida albicans. PLOS One 9(3), e92734. Details PubMed Open Access
(2014) Terrein Biosynthesis in Aspergillus terreus and Its Impact on Phytotoxicity. Chem Biol 21(6), 719-731. Details PubMed
(2013) Lysine biosynthesis in microbes: relevance as drug target and prospects for β-lactam antibiotics production. Appl Microbiol Biotechnol 97(9), 3763-3772. Details PubMed
(2013) Factors supporting cysteine tolerance and sulfite production in Candida albicans. Eukaryot Cell 12(4), 604-613. Details PubMed
(2013) Phylogenetic and phenotypic characterisation of the 3-ketoacyl-CoA thiolase gene family from the opportunistic human pathogenic fungus Candida albicans. FEMS Yeast Res 13(6), 553-564. Details PubMed
(2012) Candida albicans scavenges host zinc via Pra1 during endothelial invasion. PLOS Pathog 8(6), e1002777. Details PubMed Open Access
(2012) Persistence versus escape: Aspergillus terreus and Aspergillus fumigatus employ different strategies during interactions with macrophages. PLOS One 7(2), e31223-e31223. Details PubMed
(2012) Murine infection models for Aspergillus terreus pulmonary aspergillosis reveal long-term persistence of conidia and liver degeneration. J Infect Dis 205(8), 1268-1277. Details PubMed
(2011) Weiterentwicklung des Hühnerei-Infektionsmodells und neue Biolumineszenz-Detektionssysteme liefern genauere Aussagen bei Pilzinfektionen und antifungalen Therapien SIEMENS Forum Aktuell (4), 11-11. Details
(2011) Multifactorial induction of an orphan PKS-NRPS gene cluster in Aspergillus terreus. Chem Biol 18(2), 198-209. Details PubMed
(2011) Gene acquisition, duplication and metabolic specification: the evolution of fungal methylisocitrate lyases. Environ Microbiol 13(6), 1534-1548. Details PubMed
(2011) Molecular epidemiology and virulence assessment of Aspergillus fumigatus isolates from white stork chicks and their environment. Vet Microbiol 148(2-4), 348-355. Details PubMed
(2011) Exploring metabolic pathways in genome-scale networks via generating flux modes. Bioinformatics 27(4), 534-540. Details PubMed
(2010) Candida glabrata tryptophan-based pigment production via the Ehrlich pathway. Mol Microbiol 76(1), 25-47. Details PubMed
(2010) Embryonated eggs as an alternative infection model to investigate Aspergillus fumigatus virulence. Infect Immun 78(7), 2995-3006. Details PubMed
(2010) Evaluation of lysine biosynthesis as an antifungal drug target: biochemical characterization of Aspergillus fumigatus homocitrate synthase and virulence studies. Eukaryot Cell 9(6), 878-893. Details PubMed
(2009) Methylcitrate cycle activation during adaptation of Fusarium solani and Fusarium verticillioides to propionyl-CoA-generating carbon sources. Microbiology 155(Pt 12), 3903-3912. Details PubMed
(2008) Methylcitrate synthase from Aspergillus fumigatus is essential for manifestation of invasive aspergillosis. Cell Microbiol 10(1), 134-148. Details PubMed
(2007) Environmental dimensionality controls the interaction of phagocytes with the pathogenic fungi Aspergillus fumigatus and Candida albicans. PLOS Pathog 3(2), e13. Details PubMed
(2007) Aspergillus fumigatus does not require fatty acid metabolism via isocitrate lyase for development of invasive aspergillosis. Infect Immun 75(3), 1237-1244. Details PubMed
(2006) Analysis of the regulation, expression, and localisation of the isocitrate lyase from Aspergillus fumigatus, a potential target for antifungal drug development. Fungal Genet Biol 43(7), 476-489. Details PubMed
(2006) Characterisation of the laccase-encoding gene abr2 of the dihydroxynaphthalene-like melanin gene cluster of Aspergillus fumigatus. Arch Microbiol 186(5), 345-355. Details PubMed