Philipp Stephan

Philipp Stephan

Biosynthetic Design of Natural Products · PhD student +49 3641 532-1285 philipp.stephan@leibniz-hki.de

Curriculum vitae

Main Research Areas
  • Synthesis of Natural Products and Building Blocks
  • Isolation and Characterization of Natural Products

Publications

Müll M, Pourmasoumi F, Wehrhan L, Nosovska O, Stephan P, Zeihe H, Vilotijevic I, Keller BG, Kries H (2023) Biosynthetic incorporation of fluorinated amino acids into the nonribosomal peptide gramicidin S. RSC Chem Biol 4(9), 692-697.
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Pourmasoumi F,* Hengoju S,* Beck K, Stephan P, Klopfleisch L, Hoernke M, Rosenbaum MA, Kries H (2023) Analysing megasynthetase mutants at high throughput using droplet microfluidics. Chembiochem 24(24), e202300680.
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Stephan P, Langley C, Winkler D, Basquin J, Caputi L, O'Connor SE, Kries H (2023) Directed evolution of piperazic acid incorporation by a nonribosomal peptide synthetase. Angew Chem Int Ed Engl 62(35), e202304843.
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Stanišić A, Hüsken A, Stephan P, Niquille DL, Reinstein J, Kries H (2021) Engineered nonribosomal peptide synthetase shows opposite amino acid loading and condensation specificity. ACS Catal 11(14), 8692-8700.
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Huang HM, Stephan P, Kries H (2020) Engineering DNA-templated nonribosomal peptide synthesis. Cell Chem Biol 28(2), 221-227.
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PubMed Open Access
Guo H, Schmidt A, Stephan P, Raguž L, Braga D, Kaiser M, Dahse HM, Weigel C, Lackner G, Beemelmanns C (2018) Precursor-directed diversification of cyclic tetrapeptidic pseudoxylallemycins. ChemBioChem 19(21), 2307-2311.
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PubMed