(2025)
In vitro psilocybin synthesis by co-immobilized enzymes.
Chem Eur J 31(29),
e202501037.
Curriculum vitae
Main Research Areas
- Biochemical and genetic basis of natural product biosynthesis of basal fungi (early-diverging fungi, especially mucoromycetes und zoopagomycetes)
- pharmaceutical application and ecological significance of fungal natural products
- alternative, non-canonical strategies of fungal natural product biosynthesis
Professional Career
| since 2024 | Habilitated lecturer („Privatdozent“) at the Institute for Pharmacy, Friedrich-Schiller-University, Jena, Germany |
| 2017-2024 | State doctorate (Habilitation) in pharmaceutical microbiology at the Friedrich-Schiller-University Jena, Germany |
| 2015-2017 | Postdoctoral, Institute Pasteur, Paris, France |
| 2009-2015 | Doctoral thesis (Dr. rer. nat.) in biochemistry at the Friedrich-Schiller-University Jena and the Hans-Knöll-Institute, Jena, Germany |
| 2003-2009 | Diploma in biochemistry/molecular biology at the Friedrich-Schiller-University Jena, Germany |
Publications
(2025)
Clade III synthases add cyclic and linear terpenoids to the Psilocybe metabolome.
ChemBioChem 26(13),
e202500167.
(2024)
Beneficial soil fungus kills predatory nematodes with dehydropeptides translocating into the animal gut.
J Am Chem Soc 146(50),
34702-34710.
(2024)
Interplay between host humoral pattern recognition molecules controls undue immuneresponses against Aspergillus fumigatus.
Nat Commun 15(1),
6966.
(2024)
Parallel evolution of Asco- and Basidiomycete O-Prenyltransferases.
J Nat Prod 87(3),
576-582.
(2023)
A genetic tool to express long fungal biosynthetic genes.
Fungal Biol Biotechnol 10(1),
4.
(2023)
Basidiomycete non-reducing polyketide synthases function independently of SAT domains.
Fungal Biol Biotechnol 10(1),
17.
(2023)
Non-canonical two-step biosynthesis of anti-oomycete indole alkaloids in Kickxellales.
Fungal Biol Biotechnol 1010(1),
19.
(2023)
Insecticidal cyclodepsitetrapeptides from Mortierella alpina.
J Nat Prod 86(7),
1715-1722.
(2023)
A "Magic Mushroom" multi-product sesquiterpene synthase.
ChemBioChem 24(21),
e202300511.