(2019)
A genomics perspective on natural product biosynthesis in plant pathogenic bacteria.
Nat Prod Rep 36(2),
307-325.
(Review)
Curriculum vitae
Main Research Areas
- Quinone synthetases and related enzymes
- Polyketide synthases of basidiomycetes
- Biosynthesis of psilocybin
- Natural products of the genus Psilocybe
Professional Career
| 2014- | Full Professor for Pharmaceutical Microbiology, FSU Jena and HKI Jena |
| 2009-2014 | Associate Professor for Pharmaceutical Biology, FSU Jena and head of the associated department Pharmaceutical Biology at the HKI Jena |
| 2007-2009 | Assistant Professor (tenure track) University of Minnesota, Saint Paul, MN, USA |
| 2008 | Habilitation in Pharmaceutical Biology and Biotechnology, Albert-Ludwigs-University Freiburg |
| 2004-2007 | Junior Group Leader, Institute for Pharmacy, Albert-Ludwigs-University, Freiburg |
| 2002-2004 | Postdoc, University of Wisconsin, Madison, WI, USA (DFG-fellowship) |
| 2002 | Dr. rer. nat., Faculty of Chemistry and Pharmacy, Albert-Ludwigs-University, Freiburg |
| 1998 | Diploma in biology at the Eberhard-Karls-University, Tübingen |
Awards · Appointments · Scientific Activities
| Since 2020 | Head of the Institute for Pharmacy, FSU Jena |
| 2016-2019 | Dean for Study Affairs in the Faculty of Biology and Pharmacy, FSU Jena |
| 2013-2016 | Scientific advisory board, Vereinigung für Allgemeine und Angewandte Mikrobiologie (VAAM). |
Publications
(2019)
Diversity and bioactivity of Armillaria sesquiterpene aryl ester natural products.
Mycol Prog 18(8),
1027-1037.
(2019)
Melleolides impact fungal translation via elongation factor 2.
Org Biomol Chem 17(19),
4906-4916.
(2019)
Production options for psilocybin - The making of the magic.
Chem Eur J 25(4),
897-903.
(Review)
(2019)
Enzymatic route toward 6-methylated baeocystin and psilocybin.
ChemBioChem 20(22),
2824-2829.
(2019)
Melleolides from honey mushroom inhibit 5-lipoxygenase via Cys159.
Cell Chem Biol 26(1),
60-70.e4.
(2018)
Biocatalytic production of psilocybin and derivatives in tryptophan synthase-enhanced reactions.
Chem Eur J 24(40),
10028-10031.
(2018)
Iterative L-tryptophan methylation in Psilocybe evolved by sub-domain duplication.
ChemBioChem
[Accepted]
(2018)
Multi-genome analysis identifies functional and phylogenetic diversity of basidiomycete adenylate-forming reductases.
Fungal Genet Biol 112,
55-63.
(2018)
Occurrence of european tar spot (Rhytisma acerinum) on norway maple causing severe infections in Minnesota.
Plant Disease 102,
12.
